ANSWERS 2025
Coombs test-correct-answer-a test for the presence of anti-Rh factor antibodies
in the blood (this is often given to pregnant women that are Rh- to see if they
will mount an immune response against the blood of their fetus)
L/S ratio-correct-answer-The lecithin-sphingomyelin ratio (components of
surfactant) is a test for assessing fetal lung maturity. An L/S ratio of 2:1 or
more indicates a relatively low risk of infant respiratory distress syndrome, and
an L/S ratio of less than 1.5 is associated with a high risk of infant respiratory
distress syndrome. (from amniotic fliud)
Phosphatidyglycerol (PG)-correct-answer-2nd most abundant component in
surfactant. appears around 35wks. Presence shows lung maturity. More
accurate than L/S ratio in determining RDS risk at delivery. (from amniotic
fliud)
amniocentesis-correct-answer-the sampling of amniotic fluid using a hollow
needle inserted into the uterus, to screen for developmental abnormalities in a
fetus. 15-20wks for genetic diagnosis, 30-35 wks for lung maturity.
,Quad screen-correct-answer-the maternal blood test that includes analysis of
HCG, AFP, estriol and inhibin-A to determine risk of genetic abnormalities.
Done at 16-20wks.
Trisomy 21-correct-answer-condition in which an individual has three number
21 chromosomes, resulting in Down syndrome
Trisomy 18 (Edwards Syndrome)-correct-answer-Trisomy 18
1 in 6,000 80% are female Most die before birth
Increased risk with increased maternal age Feats:
CARDIAC: VSD/ASD, PDA, CoA, Bicuspid aortic/pulm
valve RENAL: malformations
GIT: Omphalocoele, oesophageal
atresia MSK: Arthrogryposis
DEVELOPMENT: delayed
PHYSICAL FEATS: microcephaly, prominent occiput, low-set ears,
micrognathia, cleft lip/palate, upturned nose, narrow palpabrel fissures,
hypertelorism, short sternum, ptosis, clenched hands, absent radius, webbed
2nd/3rd toes, rocker- bottom feet
50% die in first week of life
Only 8% survive beyond 1 yo
Micrognathia-Correct-Answer-Abnormally Small Chin
,Hypertelorism-Correct-Answer-Widely Spaced Eyes
Omphalocoele-Correct-Answer-Abdominal Closure Prior To Retraction Of
Intestines
Arthrogryposis-Correct-Answer-Born With Joint Contractures, Don't Move
As Normal And May Be Stuck In One Position
Trisomy 13 (Patau Syndrome)-Correct-Answer-Some Of The Characteristics
Of Patau Syndrome May Include:
small skull (microcephaly)
an abnormal opening in the skull
malformations of part of the brain
structural defects of the eyes
cleft lip or cleft palate
additional toes or fingers (polydactyly)
congenital heart disorders, such as ventricular septal defect
neural tube defect, where the spinal cord, meninges and blood vessels protrude
through a gap in the vertebrae (myelomeningocele)
malformations of the sex organs
survival beyond the neonatal period is uncommon.
, Fat Soluble Vitamins-Correct-Answer-A, D, E, K
Protein Requirements For Infant-correct-answer-2-2.5kcal/kg/day preterm:3.5-
4kcal/kg/day
pathologic jaundice-correct-answer--blood/antigen incompatibility
-appears in first 24-36 hrs of life, lasts longer than a week
-direct/conj bili >12; increase >5/day
-Coombs POSITIVE = suspect hemolytic disease of newborn due to ABO
incompatibility or underlying liver disease
-administer rhogam prenatally or post-natal exchange transfusion to prevent
Fetal Scalp Stimulation-Correct-Answer-Evaluates Fetal Response
To Tactile Stimulation Via Vaginal Examination & Scratching Of
Fetal Scalp
Accelerations On Fetal Tracing After Scalp Stimulation Should Be
Seen. No Acceleration Indicated Fetal Acidosis
Fetal Bradycardia-Correct-Answer-Possible Sign Of Heart Block Or Placental
Abruption