Lehne’s Pharmacotherapeutics 3rd
Edition Test Bank
Comprehensive Question and
Answer Guide with Expert
Rationales Covering Advanced
Practice Nursing and Physician
Assistant Pharmacotherapy Prepared for
Advanced Practice Nursing and Physician Assistant Education October 24,
2025
,Contents
1 Introduction 2
2 Prescriptive Authority and Rational Drug Selection 2
3 Basic Principles of Pharmacology and Drug Therapy Across the Life
Span 6
4 Cardiovascular and Respiratory Pharmacotherapy 10
5 Endocrine and Gastrointestinal Pharmacotherapy 11
6 Neurologic, Psychiatric, and Additional Drug Classes 13
7 Infectious Disease, Oncology, and Miscellaneous Topics 16
8 Conclusion 21
1
, 1 Introduction
This comprehensive guide serves as a focused test bank resource for advanced practice
nursing and physician assistant students and professionals. It emphasizes key pharma-
cotherapeutic concepts through multiple-choice questions, answers, and concise expert
rationales. Unnecessary jargon has been minimized to prioritize clarity and clinical rele-
vance. The content draws primarily from established educational resources aligned with
Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants,
3rd Edition, expanded with 100 additional relevant questions to enhance depth across
drug classes, interactions, patient education, and clinical scenarios. This document is
structured for easy study and review, totaling over 60 pages with approximately 200
questions and rationales.
2 Prescriptive Authority and Rational Drug Selec-
tion
1. Question: An APRN works in a urology clinic under the supervision of a physician
who does not restrict the types of medications the APRN is allowed to prescribe.
State law does not require the APRN to practice under physician supervision. How
would the APRN’s prescriptive authority be described?
a. Full authority
b. Independent
c. Without limitation
d. Limited authority
Answer: b. Independent
Rationale: Independent authority means no required physician oversight, allowing
prescribing without restrictions from the regulating body. This supports efficient
care delivery.
2. Question: Which factors increase the need for APRNs to have full prescriptive
authority?
a. More patients will have access to health care.
b. Enrollment in medical schools is predicted to decrease.
c. Physician’s assistants are being utilized less often.
d. APRN education is more complex than education for physicians.
Answer: a. More patients will have access to health care.
Rationale: Expanded health coverage increases patient volume, requiring more
independent prescribers like APRNs to meet demand.
3. Question: Which factors could be attributed to limited prescriptive authority for
APRNs? Select all that apply.
a. Inaccessibility of patient care
b. Higher health care costs
c. Higher quality medical treatment
d. Improved collaborative care
e. Enhanced health literacy
Answer: a, b
Rationale: Restrictions lead to delays in care and increased costs due to reliance
2
Edition Test Bank
Comprehensive Question and
Answer Guide with Expert
Rationales Covering Advanced
Practice Nursing and Physician
Assistant Pharmacotherapy Prepared for
Advanced Practice Nursing and Physician Assistant Education October 24,
2025
,Contents
1 Introduction 2
2 Prescriptive Authority and Rational Drug Selection 2
3 Basic Principles of Pharmacology and Drug Therapy Across the Life
Span 6
4 Cardiovascular and Respiratory Pharmacotherapy 10
5 Endocrine and Gastrointestinal Pharmacotherapy 11
6 Neurologic, Psychiatric, and Additional Drug Classes 13
7 Infectious Disease, Oncology, and Miscellaneous Topics 16
8 Conclusion 21
1
, 1 Introduction
This comprehensive guide serves as a focused test bank resource for advanced practice
nursing and physician assistant students and professionals. It emphasizes key pharma-
cotherapeutic concepts through multiple-choice questions, answers, and concise expert
rationales. Unnecessary jargon has been minimized to prioritize clarity and clinical rele-
vance. The content draws primarily from established educational resources aligned with
Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants,
3rd Edition, expanded with 100 additional relevant questions to enhance depth across
drug classes, interactions, patient education, and clinical scenarios. This document is
structured for easy study and review, totaling over 60 pages with approximately 200
questions and rationales.
2 Prescriptive Authority and Rational Drug Selec-
tion
1. Question: An APRN works in a urology clinic under the supervision of a physician
who does not restrict the types of medications the APRN is allowed to prescribe.
State law does not require the APRN to practice under physician supervision. How
would the APRN’s prescriptive authority be described?
a. Full authority
b. Independent
c. Without limitation
d. Limited authority
Answer: b. Independent
Rationale: Independent authority means no required physician oversight, allowing
prescribing without restrictions from the regulating body. This supports efficient
care delivery.
2. Question: Which factors increase the need for APRNs to have full prescriptive
authority?
a. More patients will have access to health care.
b. Enrollment in medical schools is predicted to decrease.
c. Physician’s assistants are being utilized less often.
d. APRN education is more complex than education for physicians.
Answer: a. More patients will have access to health care.
Rationale: Expanded health coverage increases patient volume, requiring more
independent prescribers like APRNs to meet demand.
3. Question: Which factors could be attributed to limited prescriptive authority for
APRNs? Select all that apply.
a. Inaccessibility of patient care
b. Higher health care costs
c. Higher quality medical treatment
d. Improved collaborative care
e. Enhanced health literacy
Answer: a, b
Rationale: Restrictions lead to delays in care and increased costs due to reliance
2
