Pharmacology 1 – Straighterline Exam
Questions With Correct Answers
adverse |effect |- |CORRECT |ANSWER✔✔-general |term |for |undesirable |and |potentially |harmful |
drug |effect.
agonist |- |CORRECT |ANSWER✔✔-drug |that |binds |to |a |receptor |and |activates |a |physiologic |
response |or |drug |action.
antagonist |- |CORRECT |ANSWER✔✔-drug |that |binds |to |a |receptor |and |interferes |with |other |
drugs |or |substances |from |producing |a |drug |effect.
chemical |name |- |CORRECT |ANSWER✔✔-name |that |defines |the |chemical |composition |of |a |
drug.
contraindications |- |CORRECT |ANSWER✔✔-situations |or |conditions |when |a |certain |drug |should
|not |be |administered.
controlled |substance |- |CORRECT |ANSWER✔✔-drug |that |has |the |potential |for |abuse |and |thus |
is |regulated |by |law.
dose |- |CORRECT |ANSWER✔✔-a |measurement |of |the |amount |of |drug |that |is |administered.
drug |- |CORRECT |ANSWER✔✔-chemical |substance |that |produces |a |change |in |body |function.
drug |indications |- |CORRECT |ANSWER✔✔-intended |or |indicated |uses |for |any |drug.
,ED50 |- |CORRECT |ANSWER✔✔-effective |dose |50, |or |dose |that |will |produce |an |effect |that |is |
half |of |the |maximal |response.
generic |name |- |CORRECT |ANSWER✔✔-nonproprietary |name |of |a |drug.
LD50 |- |CORRECT |ANSWER✔✔-lethal |dose |50, |or |dose |that |will |kill |50 |percent |of |the |
laboratory |animals |tested.
mechanism |of |action |- |CORRECT |ANSWER✔✔-explanation |of |how |a |drug |produces |its |effects.
nonprescription, |over-the-counter |(OTC) |drug |- |CORRECT |ANSWER✔✔-drug |that |can |be |
purchased |without |the |services |of |a |physician.
pharmacology |- |CORRECT |ANSWER✔✔-study |of |drugs.
potency |- |CORRECT |ANSWER✔✔-measure |of |the |strength, |or |concentration, |of |a |drug |
required |to |produce |a |specific |effect.
prescription |drug |- |CORRECT |ANSWER✔✔-drug |for |which |dispensing |requires |a |written |or |
phone |order |that |can |only |be |issued |by |or |under |the |direction |of |a |licensed |physician.
receptor |- |CORRECT |ANSWER✔✔-specific |cellular |structure |that |a |drug |binds |to |in |order |to |
produce |a |physiologic |effect.
side |effect |- |CORRECT |ANSWER✔✔-drug |effect |other |than |the |therapeutic |effect |that |is |
usually |undesirable |but |not |harmful.
,site |of |action |- |CORRECT |ANSWER✔✔-location |within |the |body |where |a |drug |exerts |its |
therapeutic |effect, |often |a |specific |drug |receptor.
therapeutic |effect |- |CORRECT |ANSWER✔✔-desired |drug |effect |to |alleviate |some |condition |or |
symptom |of |disease.
therapeutic |index |(TI) |- |CORRECT |ANSWER✔✔-ratio |of |the |LD50 |to |the |ED50 |in |animal |
studies.
toxic |effect |- |CORRECT |ANSWER✔✔-undesirable |drug |effect |that |implies |drug |poisoning; |can |
be |very |harmful |or |life-threatening.
trade |name |- |CORRECT |ANSWER✔✔-patented |proprietary |name |of |a |drug |sold |by |a |specific |
drug |manufacturer; |also |referred |to |as |the |brand |name.
bioavailability |- |CORRECT |ANSWER✔✔-percentage |of |the |drug |dosage |that |is |absorbed.
drug |absorption |- |CORRECT |ANSWER✔✔-entrance |of |a |drug |into |the |bloodstream |from |its |site
|of |administration.
drug |addiction |- |CORRECT |ANSWER✔✔-condition |of |drug |abuse |and |drug |dependence |that |is |
characterized |by |compulsive |drug |behavior.
drug |dependence |- |CORRECT |ANSWER✔✔-condition |of |reliance |on |the |use |of |a |particular |
drug, |characterized |as |physical |and/or |psychological |dependence.
drug |distribution |- |CORRECT |ANSWER✔✔-passage |of |a |drug |from |the |blood |to |the |tissues |and
|organs |of |the |body.
, drug |excretion |- |CORRECT |ANSWER✔✔-elimination |of |the |drug |from |the |body.
drug |metabolism |- |CORRECT |ANSWER✔✔-the |enzymatic |biotransformation |of |a |drug |into |
metabolites.
drug |microsomal |metabolizing |system |(DMMS) |- |CORRECT |ANSWER✔✔-group |of |enzymes |
located |primarily |in |the |liver |that |function |to |metabolize |(biotransformation) |drugs.
drug |tolerance |- |CORRECT |ANSWER✔✔-decreased |drug |effect |occurring |after |repeated |drug |
administration.
enzyme |induction |- |CORRECT |ANSWER✔✔-increase |in |the |amount |of |drug-metabolizing |
enzymes |after |repeated |administration |of |certain |drugs.
enzyme |inhibition |- |CORRECT |ANSWER✔✔-inhibition |of |drug-metabolizing |enzymes |by |certain
|drugs.
first-pass |metabolism |- |CORRECT |ANSWER✔✔-drug |metabolism |that |occurs |in |the |intestines |
and |liver |during |oral |absorption |of |drugs |into |the |systemic |circulation.
half-life |- |CORRECT |ANSWER✔✔-time |required |for |the |body |to |reduce |the |amount |of |drug |in |
the |plasma |by |one-half.
individual |variation |- |CORRECT |ANSWER✔✔-difference |in |the |effects |of |drugs |and |drug |
dosages |from |one |person |to |another.
intramuscular |(IM) |injection |- |CORRECT |ANSWER✔✔-route |of |drug |administration; |drug |is |
injected |into |gluteal |or |deltoid |muscles.
Questions With Correct Answers
adverse |effect |- |CORRECT |ANSWER✔✔-general |term |for |undesirable |and |potentially |harmful |
drug |effect.
agonist |- |CORRECT |ANSWER✔✔-drug |that |binds |to |a |receptor |and |activates |a |physiologic |
response |or |drug |action.
antagonist |- |CORRECT |ANSWER✔✔-drug |that |binds |to |a |receptor |and |interferes |with |other |
drugs |or |substances |from |producing |a |drug |effect.
chemical |name |- |CORRECT |ANSWER✔✔-name |that |defines |the |chemical |composition |of |a |
drug.
contraindications |- |CORRECT |ANSWER✔✔-situations |or |conditions |when |a |certain |drug |should
|not |be |administered.
controlled |substance |- |CORRECT |ANSWER✔✔-drug |that |has |the |potential |for |abuse |and |thus |
is |regulated |by |law.
dose |- |CORRECT |ANSWER✔✔-a |measurement |of |the |amount |of |drug |that |is |administered.
drug |- |CORRECT |ANSWER✔✔-chemical |substance |that |produces |a |change |in |body |function.
drug |indications |- |CORRECT |ANSWER✔✔-intended |or |indicated |uses |for |any |drug.
,ED50 |- |CORRECT |ANSWER✔✔-effective |dose |50, |or |dose |that |will |produce |an |effect |that |is |
half |of |the |maximal |response.
generic |name |- |CORRECT |ANSWER✔✔-nonproprietary |name |of |a |drug.
LD50 |- |CORRECT |ANSWER✔✔-lethal |dose |50, |or |dose |that |will |kill |50 |percent |of |the |
laboratory |animals |tested.
mechanism |of |action |- |CORRECT |ANSWER✔✔-explanation |of |how |a |drug |produces |its |effects.
nonprescription, |over-the-counter |(OTC) |drug |- |CORRECT |ANSWER✔✔-drug |that |can |be |
purchased |without |the |services |of |a |physician.
pharmacology |- |CORRECT |ANSWER✔✔-study |of |drugs.
potency |- |CORRECT |ANSWER✔✔-measure |of |the |strength, |or |concentration, |of |a |drug |
required |to |produce |a |specific |effect.
prescription |drug |- |CORRECT |ANSWER✔✔-drug |for |which |dispensing |requires |a |written |or |
phone |order |that |can |only |be |issued |by |or |under |the |direction |of |a |licensed |physician.
receptor |- |CORRECT |ANSWER✔✔-specific |cellular |structure |that |a |drug |binds |to |in |order |to |
produce |a |physiologic |effect.
side |effect |- |CORRECT |ANSWER✔✔-drug |effect |other |than |the |therapeutic |effect |that |is |
usually |undesirable |but |not |harmful.
,site |of |action |- |CORRECT |ANSWER✔✔-location |within |the |body |where |a |drug |exerts |its |
therapeutic |effect, |often |a |specific |drug |receptor.
therapeutic |effect |- |CORRECT |ANSWER✔✔-desired |drug |effect |to |alleviate |some |condition |or |
symptom |of |disease.
therapeutic |index |(TI) |- |CORRECT |ANSWER✔✔-ratio |of |the |LD50 |to |the |ED50 |in |animal |
studies.
toxic |effect |- |CORRECT |ANSWER✔✔-undesirable |drug |effect |that |implies |drug |poisoning; |can |
be |very |harmful |or |life-threatening.
trade |name |- |CORRECT |ANSWER✔✔-patented |proprietary |name |of |a |drug |sold |by |a |specific |
drug |manufacturer; |also |referred |to |as |the |brand |name.
bioavailability |- |CORRECT |ANSWER✔✔-percentage |of |the |drug |dosage |that |is |absorbed.
drug |absorption |- |CORRECT |ANSWER✔✔-entrance |of |a |drug |into |the |bloodstream |from |its |site
|of |administration.
drug |addiction |- |CORRECT |ANSWER✔✔-condition |of |drug |abuse |and |drug |dependence |that |is |
characterized |by |compulsive |drug |behavior.
drug |dependence |- |CORRECT |ANSWER✔✔-condition |of |reliance |on |the |use |of |a |particular |
drug, |characterized |as |physical |and/or |psychological |dependence.
drug |distribution |- |CORRECT |ANSWER✔✔-passage |of |a |drug |from |the |blood |to |the |tissues |and
|organs |of |the |body.
, drug |excretion |- |CORRECT |ANSWER✔✔-elimination |of |the |drug |from |the |body.
drug |metabolism |- |CORRECT |ANSWER✔✔-the |enzymatic |biotransformation |of |a |drug |into |
metabolites.
drug |microsomal |metabolizing |system |(DMMS) |- |CORRECT |ANSWER✔✔-group |of |enzymes |
located |primarily |in |the |liver |that |function |to |metabolize |(biotransformation) |drugs.
drug |tolerance |- |CORRECT |ANSWER✔✔-decreased |drug |effect |occurring |after |repeated |drug |
administration.
enzyme |induction |- |CORRECT |ANSWER✔✔-increase |in |the |amount |of |drug-metabolizing |
enzymes |after |repeated |administration |of |certain |drugs.
enzyme |inhibition |- |CORRECT |ANSWER✔✔-inhibition |of |drug-metabolizing |enzymes |by |certain
|drugs.
first-pass |metabolism |- |CORRECT |ANSWER✔✔-drug |metabolism |that |occurs |in |the |intestines |
and |liver |during |oral |absorption |of |drugs |into |the |systemic |circulation.
half-life |- |CORRECT |ANSWER✔✔-time |required |for |the |body |to |reduce |the |amount |of |drug |in |
the |plasma |by |one-half.
individual |variation |- |CORRECT |ANSWER✔✔-difference |in |the |effects |of |drugs |and |drug |
dosages |from |one |person |to |another.
intramuscular |(IM) |injection |- |CORRECT |ANSWER✔✔-route |of |drug |administration; |drug |is |
injected |into |gluteal |or |deltoid |muscles.
