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AANP Board Exam Study Guide 2025/2026: 340 Practice Questions & Detailed Rationales

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: Prepare with confidence for the AANP Board Exam using this comprehensive 340-question practice exam. This verified resource covers high-yield topics including dermatology, infectious diseases, pharmacology, pediatrics, diabetes management, and developmental milestones. Each question comes with a detailed answer and rationale, providing clear explanations to solidify your understanding. Perfect for NP students and graduates seeking to assess their knowledge, identify weak areas, and master the content needed to pass the AANP certification exam.

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October 16, 2025
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2025/2026
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AANP BOARD EXAM /AANP BOARD EXAM PREPARATION/AANP BOARD EXAM
PRACTICE EXAM ACTUAL EXAM 340 QUESTIONS AND CORRECT DETAILED
ANSWERS WITH RATIONALES (VERIFIED ANSWERS) 2025/2026|ALREADY GRADED
A+
What can be used to treat actinic keratosis? - ......ANSWER........Fluorouracil (5FU) or
cryotherapy

What can actinic keratosis become? - ......ANSWER........squamous cell carcinoma

When would you want to investigate further into cafe au lait spots? Why?
- ......ANSWER........When the pt has more than 6-8 spots. Can be an indication of
neurofibromatosis

What is Auspitz sign? - ......ANSWER........in psoriasis, bleeding spots when scales are
scraped off

What is the Koebner phenomenon? - ......ANSWER........New lesions appear at the site of
skin trauma for psoriasis

What antibiotics can be used in pregnancy? - ......ANSWER........Pneumonic - CAMP
Cephalosporins Amoxicillin Macrolides Penicillin

Pneumonic for pneumonia treatment? - ......ANSWER........MAD Lung Macrolides
Amoxicillin Doxycycline

Levaquin Trichomoniasis and BV are treated with what? - ......ANSWER........Flagyl

Chlamydia is treated with what? - ......ANSWER........Doxycycline or azithromycin

Gonorrhea is treated with what? - ......ANSWER........Rocephin IM

Syphilis is treated with what? - ......ANSWER........Penicillin G IM

How is strep throat treated? - ......ANSWER........Macrolides or penicillin

"Treat My throat Pain" What antibiotic is used for mastitis? - ......ANSWER........Dicloxacillin
2nd line is clindamycin

Which antibiotic is usually good for above the waist skin complaints? What about below
the waist? - ......ANSWER........Above - Keflex Below - sulfa drugs

Tetracyclines cannot be used in what pts? What is the exception to this?
- ......ANSWER........Pregnancy and <8 y/o

, 2 of 10


Exception in Rocky Mountain Spotted Fever (must be doxy) What is the first line abx for
UTI? - ......ANSWER........Macrobid

Which medication turns excretions red? - ......ANSWER........Rifampin

When is the Hep B vaccine given? - ......ANSWER........3 doses -

Birth, 1-4 months, 6-18 months When is the rotavirus vaccine given? - ......ANSWER........2
or 3 dose series Rotarix - 2 months and 4 months RotaTeq - 2 months, 4 months, 6 months

When is the DTaP vaccine given? - ......ANSWER........5 dose series: At 2, 4, and 6 months,
15-18 months, and 4-6 years

When is the Hib vaccine given? - ......ANSWER........4 dose series: 2 months 4 months 6
months Booster dose at 12-15 months

When is the PCV13 given? - ......ANSWER........4 dose series: 2 months 4 months 6 months
12-15 months

When is the IPV vaccine given? - ......ANSWER........4 dose series: 2 months 4 months 6-18
months 4-6 years

When is the MMR vaccine given? - ......ANSWER........2 dose series: 12-15 months 4-6 years

When is the varicella vaccine given? - ......ANSWER........2 dose series: 12-15 months 4-6
years

When is the hepatitis A vaccine given? - ......ANSWER........2 dose series: 12-23 months

When is the HPV vaccine given? - ......ANSWER........-2 doses if series given before age 15.
doses 6 months apart -3 dose series if given at age 15 or after.

When is the meningitis vaccine given? - ......ANSWER........2 dose series: 11-12 years 16
years

When is influenza vaccine given? - ......ANSWER........1 dose for ages 6 months and older -If
first dose in a child <9 years old, it is a 2-dose series spaced 4 weeks apart

What is a rapid acting insulin? What is the onset, peak, and duration?
- ......ANSWER........Humalog Onset - 15 minutes Peak - 1 hr Duration - 2-4 hours

What is a short acting insulin? What is the onset, peak, and duration?
- ......ANSWER........Regular Onset - 30 min to 1 hr Peak - 2-4 hrs Duration - 6-8 hrs

What is an intermediate acting insulin? What is the onset, peak, and duration?
- ......ANSWER........NPH Onset - 1-2 hrs Peak - 6-12 hrs Duration - 24 hrs
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