Page 1 of 439
MLS ASCP EXAM NEWEST 2025 ACTUAL EXAM TEST
BANK| COMPLETE 1200 REAL EXAM QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+| ASCP MLS
CERTIFICATION EXAM PREP 2025 (BRAND NEW!!)
The most commonly used challenge test to assist in evaluating a
potential growth hormone deficiency is the:
A. Insulin challenge test
B. Dexamethasone suppression test
C. Oral glucose tolerance test
D. Captopril suppression test - Correct Answer - Insulin challenge test
In the regulator type of Rh null, which of the following genes is
mutated?
A. RHAG
B. RHCE
C. RHD
D. LW - Correct Answer - A. RHAG
The major intracellular cation is which of the following?
A. Potassium
B. Sodium
pg. 1
,Page 2 of 439
C. Chloride
D. Bicarbonate - Correct Answer - A. Potassium
The type of graft rejection that occurs within minutes of a tissue
transplant is:
A. Acute
B. Chronic
C. Hyperacute
D. Accelerated - Correct Answer - C. Hyperacute
If a fasting plasma glucose level of 100 mg/dL is obtained on an
individual, the expected fasting cerebrospinal fluid (CSF) glucose level
in mg/dL would be:
A. 25
B. 50
C. 65
D. 100 - Correct Answer - C. 65
On first glance a peripheral blood smear appears to be of poor quality.
On further investigation it is determined that the smear contains
numerous smudge cells. This cellular artifact is associated with which of
the following?
A. Chronic Lymphocyte Leukemia
B. Hairy Cell Leukemia
C. Infectious Mononucleosis
pg. 2
,Page 3 of 439
D. Plasmacytic Leukemia - Correct Answer - A. Chronic lymphocytic
leukemia
In certain malignant disorders, a substance is found in the urine that
turns the urine dark brown or black on exposure of the urine to air. The
substance is:
A. Urobilinogen
B. Indican
C. Melanin
D. Porphyrin
E. 5-HIAA - Correct Answer - C. Melanin
Which of the following is a key characteristic of Coccidioides immitis?
A. Has a higher dissemination rate in white females
B. Is endemic in the Northeastern United States
C. Produces endosporulating spherules in tissue
D. Forms foot cells - Correct Answer - C. Produces endosporulating
spherules in tissue
An increased osmole gap is most commonly seen in which of the
following?
A. Type 2 diabetes
B. Pancreatitis
C. Presence of toxins such as ethanol and ethylene glycol
pg. 3
, Page 4 of 439
D. Liver failure - Correct Answer - C. Presence of toxins such as ethanol
and ethylene glycol
The peripheral blood and bone marrow picture sometimes will look
similar in myelodysplastic syndromes and some RBC disorders. Which
of the following RBC disorders tend to have a peripheral smear
appearance similar to cases of myelodysplastic syndromes?
A. Iron deficiency anemia
B. a-thalassemia minor
C. Megaloblastic anemia
D. Warm autoimmune hemolytic anemia - Correct Answer - C.
Megaloblastic anemia
The single most appropriate screening test to detect thyroid disease is:
A. THBR
B. sTSH
C. Free thyrozine index
D. TT4
E. FT4 - Correct Answer - B. sTSH
Which of the following enzymes is responsible for the conjugation of
bilirubin?
A. Biliverdin reductase
B. Peroxidase
C. UDP-glucuronyl transferase
pg. 4
MLS ASCP EXAM NEWEST 2025 ACTUAL EXAM TEST
BANK| COMPLETE 1200 REAL EXAM QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+| ASCP MLS
CERTIFICATION EXAM PREP 2025 (BRAND NEW!!)
The most commonly used challenge test to assist in evaluating a
potential growth hormone deficiency is the:
A. Insulin challenge test
B. Dexamethasone suppression test
C. Oral glucose tolerance test
D. Captopril suppression test - Correct Answer - Insulin challenge test
In the regulator type of Rh null, which of the following genes is
mutated?
A. RHAG
B. RHCE
C. RHD
D. LW - Correct Answer - A. RHAG
The major intracellular cation is which of the following?
A. Potassium
B. Sodium
pg. 1
,Page 2 of 439
C. Chloride
D. Bicarbonate - Correct Answer - A. Potassium
The type of graft rejection that occurs within minutes of a tissue
transplant is:
A. Acute
B. Chronic
C. Hyperacute
D. Accelerated - Correct Answer - C. Hyperacute
If a fasting plasma glucose level of 100 mg/dL is obtained on an
individual, the expected fasting cerebrospinal fluid (CSF) glucose level
in mg/dL would be:
A. 25
B. 50
C. 65
D. 100 - Correct Answer - C. 65
On first glance a peripheral blood smear appears to be of poor quality.
On further investigation it is determined that the smear contains
numerous smudge cells. This cellular artifact is associated with which of
the following?
A. Chronic Lymphocyte Leukemia
B. Hairy Cell Leukemia
C. Infectious Mononucleosis
pg. 2
,Page 3 of 439
D. Plasmacytic Leukemia - Correct Answer - A. Chronic lymphocytic
leukemia
In certain malignant disorders, a substance is found in the urine that
turns the urine dark brown or black on exposure of the urine to air. The
substance is:
A. Urobilinogen
B. Indican
C. Melanin
D. Porphyrin
E. 5-HIAA - Correct Answer - C. Melanin
Which of the following is a key characteristic of Coccidioides immitis?
A. Has a higher dissemination rate in white females
B. Is endemic in the Northeastern United States
C. Produces endosporulating spherules in tissue
D. Forms foot cells - Correct Answer - C. Produces endosporulating
spherules in tissue
An increased osmole gap is most commonly seen in which of the
following?
A. Type 2 diabetes
B. Pancreatitis
C. Presence of toxins such as ethanol and ethylene glycol
pg. 3
, Page 4 of 439
D. Liver failure - Correct Answer - C. Presence of toxins such as ethanol
and ethylene glycol
The peripheral blood and bone marrow picture sometimes will look
similar in myelodysplastic syndromes and some RBC disorders. Which
of the following RBC disorders tend to have a peripheral smear
appearance similar to cases of myelodysplastic syndromes?
A. Iron deficiency anemia
B. a-thalassemia minor
C. Megaloblastic anemia
D. Warm autoimmune hemolytic anemia - Correct Answer - C.
Megaloblastic anemia
The single most appropriate screening test to detect thyroid disease is:
A. THBR
B. sTSH
C. Free thyrozine index
D. TT4
E. FT4 - Correct Answer - B. sTSH
Which of the following enzymes is responsible for the conjugation of
bilirubin?
A. Biliverdin reductase
B. Peroxidase
C. UDP-glucuronyl transferase
pg. 4
