OFPSYCHA
I
HOSWARTS SCHOOL
- Anti-PSY
, CONTENTS
A short guide to use this summary - P3
Mechanism of Action of Antipsychotics - P4
First Generation Antipsychotics- P9
• Haloperidol (P10)
• Fluphenazine (P11)
• Chlorpromazine (P12)
Second generation antipsychotics - P13
• Amisulpride (P14)
• Risperidone (P15)
• Olanzapine (P16)
• Ziprazidone (P17)
• Quetiapine (P18)
• Lurazedone (P19)
• Aripiprazole (P20)
• Clozapine (P21)
, ANTI-PSYCHOTICS
Of
The whole chapter of antipsychotics must be mentally linked to
detention in Hogwarts’ Great Hall. From here there is expansion
into the different settings and characters in detention, each
representing a certain antipsychotic drug.
Follow the numbers on the pictures to guide you through the
image-linked memory palace to remember all the key facts. The
dark grey boxes are the explanations of how the images serve as
a memory jog for the specific facts.
, OF ACTION
MECHANISM
EFFECTS
3 ADVERSE
Detention = blocks
Dopamine receptors
Welcome to DETENTION!
The punishment is worse than the crime!
- 7
z
6
1
↑
5
4
-- 3
2
G
They all gather in the great hall before embarking on the journey that is detention:
1. The Room of Sad Silences
2. Hall of Hallucinations
3. The Puppet Chamber
4. The Milk Room
5. Dry Hex Hall
6. Dizzy Towers
7. Nap Nook
, The Room of Sad Silences
…is cold to the core
D receptor inhibition in mesocortical pathways can worsen negative symptoms
1
1. Sad Silences = negative symptoms
2. Core = mesoCORtical pathways
The Hall of Hallucinations
…where lies are silenced
2
D receptor inhibition in limbic pathways improve positive symptoms
1. Lies = Limbic Pathways
2. Silenced Hallucinations = Positive symptoms are treated
The Puppet Chamber
Students twitch painfully in detention when they are
yanked by their striatal muscles
3
D receptor inhibition in nigrostriatal pathways can cause
EPSEs such as akathisia, parkinsonism and dystonia
1. Striatal muscles = nigroSTRIATAL pathways
2. Twitch = EPSEs
3. Detention = Dystonia
4. Painfully = Parkinsonism
, The Milk Room
…tubes of milk are poured into a giant bubbling cauldron
giantbubbling
a
of
Inb E
D receptor inhibition in tuberoinfundibular pathway causes increased
4
prolactin leading to: menstrual irregularities, lower libido,
gynaecomastia, galactorrhoea and gain of weight.
Dry Hex Hall
A manuscript in Dry Hex Hall dictates:
Can’t see, can’t pee, can’t spit, can’t shit.
5
Blocking of muscarinic receptors can cause
anticholinergic effects such as blurry vision, urinary
retention, dry mouth and constipation.
1. Manuscript = Muscarinic receptors
2. Can’t see = blurry vision 4. Can’t spit = Dry mouth
3. Can’t pee = urinary retention 5. Can’t shit = constipation
, Dizzy Tower
…Alpha block causes a dizzy drop
6
Blocking alpha receptors can cause hypothermia and orthostatic hypotension
1. Alpha Block = Alpha Receptors are blocked
2. Dizzy = Orthostatic hypotension
3. Drop = drop in temperature ie hypothermia
Nap Nook
…Histamine Hibernation Sedation Station
7
Histamine and Serotonin receptor effects cause sedation
1. Histamine Hibernation = histamine causes sedation
2. Serotonin Sedation = Serotomin causes sedation
I
HOSWARTS SCHOOL
- Anti-PSY
, CONTENTS
A short guide to use this summary - P3
Mechanism of Action of Antipsychotics - P4
First Generation Antipsychotics- P9
• Haloperidol (P10)
• Fluphenazine (P11)
• Chlorpromazine (P12)
Second generation antipsychotics - P13
• Amisulpride (P14)
• Risperidone (P15)
• Olanzapine (P16)
• Ziprazidone (P17)
• Quetiapine (P18)
• Lurazedone (P19)
• Aripiprazole (P20)
• Clozapine (P21)
, ANTI-PSYCHOTICS
Of
The whole chapter of antipsychotics must be mentally linked to
detention in Hogwarts’ Great Hall. From here there is expansion
into the different settings and characters in detention, each
representing a certain antipsychotic drug.
Follow the numbers on the pictures to guide you through the
image-linked memory palace to remember all the key facts. The
dark grey boxes are the explanations of how the images serve as
a memory jog for the specific facts.
, OF ACTION
MECHANISM
EFFECTS
3 ADVERSE
Detention = blocks
Dopamine receptors
Welcome to DETENTION!
The punishment is worse than the crime!
- 7
z
6
1
↑
5
4
-- 3
2
G
They all gather in the great hall before embarking on the journey that is detention:
1. The Room of Sad Silences
2. Hall of Hallucinations
3. The Puppet Chamber
4. The Milk Room
5. Dry Hex Hall
6. Dizzy Towers
7. Nap Nook
, The Room of Sad Silences
…is cold to the core
D receptor inhibition in mesocortical pathways can worsen negative symptoms
1
1. Sad Silences = negative symptoms
2. Core = mesoCORtical pathways
The Hall of Hallucinations
…where lies are silenced
2
D receptor inhibition in limbic pathways improve positive symptoms
1. Lies = Limbic Pathways
2. Silenced Hallucinations = Positive symptoms are treated
The Puppet Chamber
Students twitch painfully in detention when they are
yanked by their striatal muscles
3
D receptor inhibition in nigrostriatal pathways can cause
EPSEs such as akathisia, parkinsonism and dystonia
1. Striatal muscles = nigroSTRIATAL pathways
2. Twitch = EPSEs
3. Detention = Dystonia
4. Painfully = Parkinsonism
, The Milk Room
…tubes of milk are poured into a giant bubbling cauldron
giantbubbling
a
of
Inb E
D receptor inhibition in tuberoinfundibular pathway causes increased
4
prolactin leading to: menstrual irregularities, lower libido,
gynaecomastia, galactorrhoea and gain of weight.
Dry Hex Hall
A manuscript in Dry Hex Hall dictates:
Can’t see, can’t pee, can’t spit, can’t shit.
5
Blocking of muscarinic receptors can cause
anticholinergic effects such as blurry vision, urinary
retention, dry mouth and constipation.
1. Manuscript = Muscarinic receptors
2. Can’t see = blurry vision 4. Can’t spit = Dry mouth
3. Can’t pee = urinary retention 5. Can’t shit = constipation
, Dizzy Tower
…Alpha block causes a dizzy drop
6
Blocking alpha receptors can cause hypothermia and orthostatic hypotension
1. Alpha Block = Alpha Receptors are blocked
2. Dizzy = Orthostatic hypotension
3. Drop = drop in temperature ie hypothermia
Nap Nook
…Histamine Hibernation Sedation Station
7
Histamine and Serotonin receptor effects cause sedation
1. Histamine Hibernation = histamine causes sedation
2. Serotonin Sedation = Serotomin causes sedation
