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NR 507 Advanced Pathophysiology Week 5: Edapt - Obstructive GI Disorders Overview and Management 2025 Chamberlain College of Nursing

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NR 507 Advanced Pathophysiology Week 5: Edapt - Obstructive GI Disorders Overview and Management 2025 Chamberlain College of Nursing

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NR 507 Advanced Pathophysiology Week 5: Edapt -
Obstructive GI Disorders Overview and
Management 2025 Chamberlain College of Nursing




NR 507: Week 5 Edapt: Obstructive Gastrointestinal Disorders
Obstructive gastrointestinal disorders like esophageal stricture and appendicitis occur with a
tightening or complete blockage of a part of the system. These can be deemed medical
emergencies in certain situations, but treatment is also available depending on the severity.




Chronic inflammation and the development of scar tissue are key contributors to the
development of esophageal strictures. Prolonged irritation and injury to the esophageal
mucosa trigger a reparative response, leading to the formation of scar tissue and thickening
of the esophageal wall, ultimately resulting in stricture formation.

Excessive gastric acid may contribute to esophageal injury but does not directly lead to
scar tissue formation. Accumulation of mucus and debris may cause obstruction but is not

, a primary cause of esophageal stricture. Rapid cell proliferation is not a typical feature in
the pathophysiology of esophageal strictures.




he most common cause of appendicitis is the obstruction of the appendix by a fecalith
(hardened stool), leading to a buildup of bacteria, inflammation, and ultimately
appendicitis.

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