Practice Exam Questions And
Correct Answers (Verified Answers)
Plus Rationales 2025 Q&A | Instant
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1. Which hormone stimulates glycogen breakdown in the
liver?
Glucagon
Glucagon activates glycogen phosphorylase, promoting
glycogenolysis to increase blood glucose.
2. The primary site for gluconeogenesis is:
Liver
The liver is the main organ for producing glucose from non-
carbohydrate sources.
,3. Which enzyme is regulated by insulin to promote glycolysis?
Phosphofructokinase-1 (PFK-1)
Insulin activates PFK-1 indirectly, increasing glycolysis.
4. Which hormone opposes insulin’s action?
Glucagon
Glucagon increases blood glucose by stimulating
glycogenolysis and gluconeogenesis.
5. Which tissue depends almost entirely on glucose for
energy?
Brain
The brain has high energy demands and relies on glucose
under normal conditions.
6. During fasting, which fuel source becomes major for
muscle?
Fatty acids
Muscles shift to fatty acid oxidation to spare glucose for the
brain.
7. What is the major product of lipolysis?
Free fatty acids
Lipolysis breaks triglycerides into free fatty acids and
glycerol.
,8. Which enzyme activates fatty acids for oxidation?
Acyl-CoA synthetase
This enzyme converts fatty acids to acyl-CoA for transport
into mitochondria.
9. Which organ is the primary site for ketone body synthesis?
Liver
The liver produces ketone bodies during prolonged fasting
or low-carbohydrate intake.
10. Which molecule is the precursor for ketone bodies?
Acetyl-CoA
Acetyl-CoA from fatty acid oxidation is used for ketone
synthesis.
11. Which hormone stimulates lipogenesis?
Insulin
Insulin promotes fat synthesis by activating acetyl-CoA
carboxylase.
12. Which process occurs when insulin levels are high?
Glycogenesis
High insulin promotes glycogen synthesis to store glucose.
13. Which hormone increases glucose uptake in muscle
and adipose tissue?
Insulin
, Insulin stimulates GLUT4 translocation to the cell
membrane.
14. What is the main energy source for RBCs?
Glucose
RBCs lack mitochondria and rely entirely on glycolysis for
ATP.
15. Which hormone increases protein degradation in
muscle during fasting?
Cortisol
Cortisol mobilizes amino acids for gluconeogenesis under
stress or fasting.
16. Which lipoprotein delivers triglycerides to tissues?
Chylomicrons
Chylomicrons transport dietary lipids to peripheral tissues.
17. Which enzyme hydrolyzes triglycerides in
chylomicrons?
Lipoprotein lipase
This enzyme releases free fatty acids from chylomicrons for
tissue uptake.
18. Which metabolic pathway generates NADPH for fatty
acid synthesis?
Pentose phosphate pathway