Test bank for Tietz Fundamentals of Clinical Chemistry
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8th Edition by Nader Rifai, PhD
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Chapters 1 - 49 hh hh hh hh
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation hh hh
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones hh hh
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes hh hh
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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TestBank
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MULTIPLE CHOICE hh
1. An individual working in a clinical chemistry laboratory is married to a sales
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representative who works for a company that sells chemistry laboratory supplies. When
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the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
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this individual onlyrecommends the spouse’s company as the vendor. This is considered to
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be a(n):
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a. accounting issue. hh
b. possible conflict of interest. hh hh hh
c. maintenance of confidentiality issue. hh hh hh
d. problem with resource allocation. hh hh hh
ANS: B hh
Concern has been raised over the interrelationships between practitioners in the medical
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fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
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profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and
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manufacturers and providers of diagnostic equipment and supplies. These concerns led the
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National Institutes of Health (NIH) in 1995 to require official institutional review of
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financial disclosure by researchers and management of situations in which disclosure
hh hh hh hh hh hh hh hh hh hh hh
indicates potentialconflicts of interest.
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DIF: 1 REF: hh hh hh Page 4-5 hh OBJ: 6 | 7 hh hh hh
2. A patient visits her physician stating that her prescribed painkiller is not working to
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reduce the pain following her recent surgery. A friend of the patient claims that the same
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painkiller―worked wonders‖ to reduce her pain after the same surgery. The physician
hh h hh hh hh hh hh hh hh hh hh hh hh
states that the difference in the effect of the drug might be caused by , which is studied
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in pharmacogenetics.
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a. epidemiology
b. an inherited disease hh hh
c. a conflict of interest
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d. a genetic variation in drug-metabolizing enzymes
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ANS: D hh
Pharmacogenetics is the study of the genetic variation of drug metabolism hh hh hh hh hh hh hh hh hh hh
betweenindividuals.
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DIF: 1 REF: hh hh h h Page 3 hh OBJ: 1 hh
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
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the name of a close friend printed on the bar-coded label. The genetic test that is ordered
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on thefriend’s sample would provide diagnostic information about a disorder that has a
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poor prognosis, and the test is usually performed by John. He asks a fellow employee to
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analyzethe sample for him and not divulge the results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. hh hh hh hh hh hh
b. a conflict of interest.
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c. resource allocation. hh
d. diagnostic accuracy. hh
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hh and Molecular Diagnostics,
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8th Edition by Nader Rifai, PhD
hh hh hh hh hh hh
Chapters 1 - 49 hh hh hh hh
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
hh hh hh hh hh hh hh hh
hh
hh hh
Table of contents:
hh hh
I. Principles Of Laboratory Medicine
hh hh hh hh
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
hh hh hh hh hh hh hh hh
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
hh hh hh hh hh hh hh hh hh hh hh
Chapter 3. Clinical Evaluation of Methods
hh hh hh hh hh
Chapter 4. Evidence-Based Laboratory Medicine
hh hh hh hh
Chapter 5. Establishment and Use of Reference Values
hh hh hh hh hh hh hh
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
hh hh hh hh hh hh hh hh
Chapter 7. Quality Management
hh hh hh
II. Analytical Techniques And Instrumentation
hh hh hh hh
Chapter 8. Principles of Basic Techniques and Laboratory Safety
hh hh hh hh hh hh hh hh
Chapter 9. Optical Techniques
hh hh hh
Chapter 10. Electrochemistry and Chemical Sensors
hh hh hh hh hh
Chapter 11. Electrophoresis
hh hh
Chapter 12. Chromatography
hh hh
Chapter 13. Mass Spectrometry
hh hh hh
Chapter 14. Enzyme and Rate Analyses
hh hh hh hh hh
Chapter 15. Immunochemical Techniques
hh hh hh
Chapter 16 Automation hh hh
Chapter 17. Point-of-Care Instrumentation
hh hh hh
III. Analytes
h h
Chapter 18. Amino Acids, Peptides, and Proteins
hh hh hh hh hh hh
Chapter 19. Serum Enzymes
hh hh hh
Chapter 20. Tumor Markers and Cancer Genes
hh hh hh hh hh hh
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
hh hh hh hh hh hh hh hh hh hh hh
Chapter 22. Carbohydrates
hh hh
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
hh hh hh hh hh hh hh hh hh
Chapter 24. Electrolytes and Blood Gases
hh hh hh hh hh
Chapter 25. Hormones hh hh
Chapter 26. Catecholamines and Serotonin
hh h h hh hh
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
hh h h hh hh hh hh
Chapter 28. Hemoglobin, Iron, and Bilirubin
hh hh hh hh hh
Chapter 29. Porphyrins and Porphyrias
hh hh hh hh
Chapter 30. Therapeutic Drugs and Their Management
hh hh hh hh hh hh
Chapter 31. Clinical Toxicology
hh hh hh
Chapter 32. Toxic Metals
hh h h hh
IV. Pathophysiology
h h
Chapter 33. Diabetes hh hh
,Chapter 34. Cardiovascular Disease
hh h h hh
Chapter 35. Kidney Disease
hh hh hh
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
hh h h hh hh hh hh hh hh hh hh
Chapter 37. Liver Disease
hh hh hh hh
Chapter 38. Gastrointestinal and Pancreatic Diseases
hh h h hh hh hh
Chapter 39. Disorders of Bone and Mineral Metabolism
hh hh hh hh hh hh hh hh
Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
hh h h hh hh hh hh
Chapter 42. Thyroid Disorders
hh h h hh
Chapter 43. Reproduction-Related Disorders
hh h h hh
Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
hh h h hh hh hh hh hh hh
Chapter 46. Pharmacogenetics
hh hh
V. Molecular Diagnostics
h h hh
Chapter 47. Principles of Molecular Biology
hh hh hh hh hh
Chapter 48. Nucleic Acid Techniques and Applications
hh hh hh hh hh hh
Chapter 49. Genomes and Nucleic Acid Alterations
hh hh hh hh hh hh
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
hh hh hh hh hh hh hh hh
TestBank
hh h
MULTIPLE CHOICE hh
1. An individual working in a clinical chemistry laboratory is married to a sales
hh hh hh hh hh hh hh hh hh hh hh hh
representative who works for a company that sells chemistry laboratory supplies. When
hh hh hh hh hh hh hh hh hh hh hh hh
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
hh hh hh hh hh hh hh hh hh hh hh hh hh hh
this individual onlyrecommends the spouse’s company as the vendor. This is considered to
hh hh hh h hh hh hh hh hh hh hh hh hh hh
be a(n):
hh hh
a. accounting issue. hh
b. possible conflict of interest. hh hh hh
c. maintenance of confidentiality issue. hh hh hh
d. problem with resource allocation. hh hh hh
ANS: B hh
Concern has been raised over the interrelationships between practitioners in the medical
hh hh hh hh hh hh hh hh hh hh hh
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
hh h hh hh hh hh hh hh hh hh hh hh
profession.
hh
Similarly, relationships have been scrutinized between clinical laboratorians and
hh hh hh hh hh hh hh hh
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
hh hh hh hh hh hh hh hh hh hh hh hh
National Institutes of Health (NIH) in 1995 to require official institutional review of
hh hh hh hh hh hh hh hh hh hh hh hh hh
financial disclosure by researchers and management of situations in which disclosure
hh hh hh hh hh hh hh hh hh hh hh
indicates potentialconflicts of interest.
hh hh h hh hh
DIF: 1 REF: hh hh hh Page 4-5 hh OBJ: 6 | 7 hh hh hh
2. A patient visits her physician stating that her prescribed painkiller is not working to
hh hh hh hh hh hh hh hh hh hh hh hh hh
reduce the pain following her recent surgery. A friend of the patient claims that the same
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
painkiller―worked wonders‖ to reduce her pain after the same surgery. The physician
hh h hh hh hh hh hh hh hh hh hh hh hh
states that the difference in the effect of the drug might be caused by , which is studied
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
in pharmacogenetics.
hh hh
a. epidemiology
b. an inherited disease hh hh
c. a conflict of interest
hh hh hh
d. a genetic variation in drug-metabolizing enzymes
hh hh hh hh hh
ANS: D hh
Pharmacogenetics is the study of the genetic variation of drug metabolism hh hh hh hh hh hh hh hh hh hh
betweenindividuals.
hh h
DIF: 1 REF: hh hh h h Page 3 hh OBJ: 1 hh
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
hh hh hh hh hh hh hh hh hh hh hh hh hh
the name of a close friend printed on the bar-coded label. The genetic test that is ordered
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
on thefriend’s sample would provide diagnostic information about a disorder that has a
hh hh h hh hh hh hh hh hh hh hh hh hh hh
poor prognosis, and the test is usually performed by John. He asks a fellow employee to
hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh hh
analyzethe sample for him and not divulge the results. This ethical issue concerns:
hh h hh hh hh hh hh hh hh hh hh hh hh hh
a. confidentiality of patient genetic and medical information. hh hh hh hh hh hh
b. a conflict of interest.
hh hh hh
c. resource allocation. hh
d. diagnostic accuracy. hh