2025/2026 Update) – Advanced
Pathophysiology
Complete Guide with Questions and Verified Answers | 100%
Correct | Grade A – Chamberlain
Contents
1 Introduction 2
2 Final Exam Questions and Answers 2
NR507 Final Exam | Advanced Pathophysiology | Verified Questions | Chamberlain | 100%
Correct | 2025/2026 | Page 1
,1 Introduction
This document provides a complete guide to the NR507 Advanced Patho-
physiology Final Exam at Chamberlain University, fully updated for the
2025/2026 academic year. It includes verified, 100% correct answers and
clinically accurate rationales covering high-yield systems and disease mech-
anisms. Ideal for MSN and NP students seeking to pass with excellence.
2 Final Exam Questions and Answers
The following 75 NCLEX-style multiple-choice questions reflect the NR507
Final Exam format. Each question includes four answer options (A–D),
with the correct answer highlighted in bold green. Clinically accurate
rationales explain the pathophysiology and clinical reasoning.
1. What is the primary pathophysiological mechanism of left-sided heart
failure?
(a) Decreased preload
(b) Pulmonary congestion
(c) Systemic edema
(d) Coronary artery occlusion
Rationale: Left-sided heart failure impairs left ventricular pumping, causing blood
to back up into the lungs, leading to pulmonary congestion (McCance & Huether,
2022).
2. Which electrolyte imbalance is most associated with diabetic ketoaci-
dosis (DKA)?
(a) Hypercalcemia
(b) Hypokalemia
(c) Hyponatremia
(d) Hypermagnesemia
Rationale: DKA causes potassium shifts due to acidosis and insulin deficiency,
leading to hypokalemia despite initial hyperkalemia.
NR507 Final Exam | Advanced Pathophysiology | Verified Questions | Chamberlain | 100%
Correct | 2025/2026 | Page 2
, 3. What is the hallmark feature of chronic obstructive pulmonary disease
(COPD)?
(a) Airway obstruction
(b) Pulmonary edema
(c) Bronchial dilation
(d) Alveolar overinflation
Rationale: COPD is characterized by irreversible airflow limitation due to airway
obstruction from inflammation and mucus.
4. Which process initiates atherosclerosis?
(a) Endothelial injury
(b) Platelet aggregation
(c) Smooth muscle relaxation
(d) Lipid metabolism
Rationale: Endothelial injury triggers inflammation and lipid accumulation, form-
ing atherosclerotic plaques.
5. A patient with acute kidney injury (AKI) is most at risk for which
complication?
(a) Hypoglycemia
(b) Hyperkalemia
(c) Hypocalcemia
(d) Hypermagnesemia
Rationale: AKI impairs potassium excretion, leading to hyperkalemia, which can
cause cardiac arrhythmias.
6. What is the primary cause of type 1 diabetes mellitus?
(a) Insulin resistance
(b) Autoimmune beta-cell destruction
(c) Pancreatic enzyme deficiency
NR507 Final Exam | Advanced Pathophysiology | Verified Questions | Chamberlain | 100%
Correct | 2025/2026 | Page 3