TEST BANK Cellular and Molecular Immunology Abul Abbas, Andrew Lichtman, and Shiv Pillai 10th Edition

TEST BANK
Cellular and Molecular Immunology


Abul Abbas, Andrew Lichtman, and Shiv Pillai
10th Edition




PlusBay.Plus

,TablewkofwkContents

Chapterwk01wkPropertieswkandwkOverviewwkofwkImmunewkResponses 1
Chapterwk02wkCellswkandwkTissueswkofwkthewkImmunewkSystem 3
Chapterwk03wkLeukocytewkCirculationwkandwkMigrationwkIntowkTissues 6
Chapterwk04wkInnatewkImmunity 10
Chapterwk05wkAntibodieswkandwkAntigens 17
Chapterwk06wkAntigenwkPresentationwktowkTwkLymphocyteswkandwkthewkFunctionswkofwkMajor
HistocompatibilitywkComplexwkMolecules 20
Chapterwk07wkImmunewkReceptorswkandwkSignalwkTransduction 27
Chapterwk08wkLymphocytewkDevelopmentwkandwkAntigenwkReceptorwkGenewkRearrangement 30
Chapterwk09wkActivationwkofwkTwkLymphocytes 34
Chapterwk10wkDifferentiationwkandwkFunctionswkofwkCD4+wkEffectorwkTwkCells 38
Chapterwk11wkDifferentiationwkandwkFunctionswkofwkCD8+wkEffectorwkTwkCells 42
Chapterwk12wkBwkCellwkActivationwkandwkAntibodywkProduction 46
Chapterwk13wkEffectorwkMechanismswkofwkHumoralwkImmunity 52
Chapterwk14wkSpecializedwkImmunitywkatwkEpithelialwkBarrierswkandwkinwkImmunewkPrivilegedwkTissues 56
Chapterwk15wkImmunologicwkTolerancewkandwkAutoimmunity 62
Chapterwk16wkImmunitywktowkMicrobes 67
Chapterwk17wkTransplantationwkImmunology 72
Chapterwk18wkTumorwkImmunology 77
Chapterwk19wkHypersensitivitywkDisorders 81
Chapterwk20wkAllergy 86
Chapterwk21wkPrimarywkandwkAcquiredwkImmunodeficiencies 89




PlusBay.Plus

,Chapterwk01:wkPropertieswkandwkOverviewwkofwkImmunewkResponses
Abbas,wkLichtman,wkandwkPillai:wkCellularwkandwkMolecularwkImmunology,wk10thwkEdition


MULTIPLEwkCHOICE

1. Thewkprincipalwkfunctionwkofwkthewkimmunewksystemwkis:
a. Defensewkagainstwkcancer
b. Repairwkofwkinjuredwktissues
c. Defensewkagainstwkmicrobialwkinfections
d. Preventionwkofwkinflammatorywkdiseases
e. Protectionwkagainstwkenvironmentalwktoxins
ANS:w k w k C
Thewkimmunewksystemwkhaswkevolvedwkinwkthewksettingwkofwkselectivewkpressureswkimposedw
kbywkmicrobialwkinfections.wkAlthoughwkimmunewkresponseswktowkcancerwkmaywkoccur,wkthew
kconceptwkthatwk“immunosurveillance”wkagainstwkcancerwkiswkawkprincipalwkfunctionwkofwkthe
wkimmunewksystemwkiswkcontroversial.wkRepairwkofwkinjuredwktissueswkmaywkbewkawksecondar
ywkconsequencewkofwkthewkimmunewkresponseswkandwkinflammation.wkAlthoughwkthewkimmu
newksystemwkhaswkregulatorywkfeatureswkthatwkarewkneededwktowkpreventwkexcessivewkinflamm
ation,wkpreventionwkofwkinflammatorywkdiseaseswkiswknotwkawkprimarywkfunction.wkThewkimm
unewksystemwkcanwkprotectwkagainstwkmicrobialwktoxins,wkbutwkitwkgenerallywkdoeswknotwkoffe
rwkprotectionwkagainstwktoxinswkofwknonbiologicwkorigin.

2. Whichwkofwkthewkfollowingwkinfectiouswkdiseaseswkwaswkpreventedwkbywkthewkfi
rstwksuccessfulwkvaccination?
a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
ANS:w k w k C
Inwk1798,wkEdwardwkJennerwkreportedwkthewkfirstwkintentionalwksuccessfulwkvaccination,wk
whichwkwaswkagainstwksmallpoxwkinwkawkboy,wkusingwkmaterialwkfromwkthewkcowpoxwkpust
uleswkofwkawkmilkmaid.wkInwk1980,wksmallpoxwkwaswkreportedwktowkbewkeradicatedwkworld
widewkbywkawkvaccinationwkprogram.wkEffectivewkvaccineswkagainstwktetanuswktoxin,wkrube
llawkvirus,wkandwkpolioviruswkwerewkdevelopedwkinwkthewk20thwkcenturywkandwkarewkwidely
wkused.wkTherewkiswknowkeffectivewkvaccinewkagainstwkMycobacteriumwktuberculosis.


3. Whichwkofwkthewkfollowingwkiswkawkuniquewkpropertywkofwkthewkadaptivewkimmunewksystem?
a. Highlywkdiversewkrepertoirewkofwkspecificitieswkforwkantigens
b. Self-nonselfwk discrimination
c. Recognitionwkofwkmicrobialwkstructureswkbywkbothwkcell-
associatedwkandwksolublewkreceptors
d. Protectionwkagainstwkviralwkinfections
e. Responseswkthatwkhavewkthewksamewkkineticswkandwkmagnitudewkonwkrepeatedwke
xposurewktowkthewksamewkmicrobe
ANS:w k w k A




PlusBay.Plus

, HighlywkdiversewkrepertoireswkofwkspecificitieswkforwkantigenswkarewkfoundwkonlywkinwkTwk
andwkBwklymphocytes,wkwhichwkarewkthewkcentralwkcellularwkcomponentswkofwkthewkadapti
vewkimmunewksystem.wkBothwkthewkinnatewkandwkthewkadaptivewkimmunewksystemswkusewkc
ell-
associatedwkandwksolublewkreceptorswktowkrecognizewkmicrobes,wkdisplaywksomewkdegreewk
ofwkself-
nonselfwkdiscrimination,wkandwkprotectwkagainstwkviruses.wkOnwkrepeatedwkexposurewktowkt
hewksamewkmicrobe,wkthewkadaptivewkimmunewkresponsewkbecomeswkmorewkrapidwkandwkof
wkgreaterwkmagnitude;wkthiswkiswkthewkmanifestationwkofwkmemory.


4. AntibodieswkandwkTwklymphocyteswkarewkthewkrespectivewkmediatorswkofwkwhich
wktwowktypeswkofwkimmunity?
a. Innatewkandwkadaptive
b. Passivewkandwkactive
c. Specificwkandwknonspecific
d. Humoralwkandwkcell-mediated
e. Adultwkandwkneonatal
ANS:w k w k D
BothwkBwkandwkTwklymphocyteswkarewkprincipalwkcomponentswkofwkadaptivewkimmunity.wk
Bwklymphocyteswkproducewkantibodies,wkwhichwkarewkthewkrecognitionwkandwkeffectorwkmol
eculeswkofwkhumoralwkimmunewkresponseswktowkextracellularwkpathogens.wkTwkcellswkrecog
nizewkandwkpromotewkeradicationwkofwkintracellularwkpathogenswkinwkcell-
mediatedwkimmunity.wkPassivewkandwkactivewkimmunitywkbothwkcanwkbewkmediatedwkbywkeit
herwkBwkorwkTwklymphocytes.wkSpecificwkimmunitywkiswkanotherwktermwkforwkadaptivewkim
munity.wkBothwkBwkandwkTwklymphocyteswkparticipatewkinwkadultwkadaptivewkimmunitywkb
utwkarewkstillwkdevelopingwkinwkthewkneonatalwkperiod.

5. ThewktwowkmajorwkfunctionalwkclasseswkofwkeffectorwkTwklymphocyteswkare:
a. HelperwkTwklymphocyteswkandwkcytotoxicwkTwklymphocytes
b. NaturalwkkillerwkcellswkandwkcytoWtoWxW
ic.TTlBSM
ymph.oW
cyStes
c. MemorywkTwkcellswkandwkeffectorwkTwkcells
d. Helperwkcellswkandwkantigen-presentingwkcells
e. CytotoxicwkTwklymphocyteswkandwktargetwkcells
ANS:w k w k A
Twkcellswkcanwkbewkclassifiedwkintowkeffectorwksubsetswkthatwkperformwkdifferentwkeffectorw
kfunctions.wkMostwkeffectorwkTwkcellswkarewkeitherwkhelperwkTwklymphocytes,wkwhichwkenh
ancewkthewkresponseswkofwkotherwkimmunewkcells,wkincludingwkphagocyteswkandwkBwkcells,
wktowkinfections,wkorwkcytotoxicwkTwklymphocytes,wkwhichwkdirectlywkkillwkinfectedwkcells.
wkNaturalwkkillerwkcellswkarewknotwkTwklymphocytes.
Antigen-
presentingwkcellswkusuallywkarewknotwkTwkcells.wkMemorywkTwkcellswkarewknotwkeffectorwkTwkce
lls.

6. Whichwkofwkthewkfollowingwkcellwktypeswkiswkrequiredwkforwkallwkadaptivewkhumoralwkimmune
wkresponses?
a. Naturalwkkillerwkcells
b. Dendriticwkcells
c. CytolyticwkTwklymphocytes
d. Bwklymphocytes
e. HelperwkTwklymphocytes
ANS:w k w k D




PlusBay.Plus