Test bank for Tietz Fundamentals of Clinical Chemistry 8th Edition by Nader Rifai, PhD

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Test bank for Tietz Fundamentals of Clinical Chemistry
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and Molecular Diagnostics 8th Edition
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byNader Rifai, PhD Chapters 1 - 49
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Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents: s s




I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and LaboratoryMedicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based LaboratoryMedicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. QualityManagement
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and LaboratorySafety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistryand Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation s s




Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones s s




Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes s s

,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the PituitaryGland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancyand Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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Chapter01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine TestBank
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MULTIPLE CHOICE s




1. An individual working in a clinical chemistry laboratory is married to a sales representative who
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works for a company that sells chemistry laboratory supplies. When the laboratory manager
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requests a list of needed supplies, cost of supplies, and vendors, this individual only recommends the
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spouse’s companyas the vendor. This is considered to be a(n):
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a. accounting issue. s




b. possible conflict of interest. s s s




c. maintenance ofconfidentiality issue. s s s




d. problemwith resource allocation. s s s




ANS: B s




Concern has been raised over the interrelationships between practitioners in the medical field and
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commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers and
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providers of diagnostic equipment and supplies. These concerns led the National Institutes of Health
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(NIH) in 1995 to require official institutional review of financial disclosure byresearchers and
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management ofsituations inwhich disclosure indicates potential conflicts of interest.
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DIF: 1 REF: Page 4-5 sss s OBJ: 6 |7 s s s




2. A patient visits her physician stating that her prescribed painkiller is not working to reduce the pain
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following her recent surgery. A friend of the patient claims that the same painkiller “worked
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wonders” to reduce her pain after the same surgery. The physician states that the difference in the
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effect of the drug might be caused by
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spharmacogenetics.
a. epidemiology
b. an inherited disease s s




c. aconflict of interest
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d. agenetic variation in drug-metabolizing enzymes
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ANS: D s




Pharmacogenetics is the studyofthe genetic variation ofdrug metabolism between individuals. s s s s s s s s s s s s




DIF: 1 REF: Page 3 ss s s OBJ: 1 s




3. John works in a molecular diagnostics laboratory and receives a blood sample that has the name ofa
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close friend printed on the bar-coded label. The genetic test that is ordered on the friend’s sample
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would provide diagnostic information about a disorder that has a poor prognosis, and the test is
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usually performed by John. He asks a fellow employee to analyze the sample for him and not
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divulge the results. This ethical issue concerns:
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a. confidentialityofpatient genetic and medical information. s s s s s s




b. aconflict of interest.
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c. resource allocation. s