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Lecture notes Cells (BIO0001)

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Detailed lecture notes on osmosis, a fundamental process in cell biology (BIO0001). These notes thoroughly explain the movement of water across selectively permeable membranes from an area of high water concentration to an area of low water concentration. 1 Key concepts such as osmotic pressure, tonicity (including the effects of hypertonic, hypotonic, and isotonic environments on cells), and the importance of osmosis in maintaining cellular volume and function are discussed.  

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May 11, 2025
Number of pages
4
Written in
2024/2025
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Micheles
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Bio – week 5 – lecture 1 – 31/3/25 – Osmosis

Centrosomes = Chromosomes can be attached by their
centromeres to structures called centrosomes.

Terminology:
If a solute can pass through a membrane, we say…
- The membrane is permeable to the solute
- The solute is permeant to the membrane.

Moles and molarity:
A “mole” of particles is about 600,000,000,000,000,000,000,000 particles or 6x10^23
particles
- We use moles for comparing concentrations. 6 x 10^23 glucose molecules in a Litre
of solution is a 1 mol/L glucose solution.
- Mol/L is pronounced “moles per litre” but we can also say “Molar” abbreviated “M”.
- Concentration is sometimes called “molarity”
- In biology, we’re normally interested in lower concentrations, so we use mmol/L (or
mM), umol/L (or uM), and nmol/L (or nM = 1 billion of a litre).

Moles and osmoles:




How to work out osmosis question:
Think about solutes first. Are any dissociative? Are any permeant (usually gases and small
uncharged molecules)? Remember that permanent solutions will move according to their
ow concentration gradients
- Remember water will move towards the higher total solute concentration
(osmolarity).

Hypertonic solution = solution has a higher solute concentration than cell -> water moves
out of cell.
Isotonic solution = concentration of solutes inside the cell is same as concentration outside -
> no net movement of water in or out which is an isotonic solution.
Hypotonic solution = solution lower solute concentration than cell -> water moves into cell.
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