BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION KA
ol ol ol ol ol ol
TZUNG TREVOR TEST BANK
ol ol ol
INCLUSIVE OF CHAPTERS 1-66 COMPLETE WITH EXPLAINED ANSWERS
ol ol ol ol ol ol ol
, Page 2 of 822 ol ol ol
Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
ol ol ol ol ol ol ol ol o l
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
ol ol ol ol ol ol ol ol ol ol ol
1.
A nurse working in radiology administers iodine to a patient who is havin
ol ol ol ol ol ol ol ol ol ol ol ol
g a computed tomography (CT) scan. The nurse working on the oncology un
ol ol ol ol ol ol ol ol ol ol ol ol
it administers chemotherapy to patients who have cancer. At the Public Healt
ol ol ol ol ol ol ol ol ol ol ol
h Department, a nurse administers a measles-mumps-
ol ol ol ol ol ol
rubella (MMR) vaccine to a 14-month- ol ol ol ol ol
old child as a routine immunization. Which branch of pharmacology best des
ol ol ol ol ol ol ol ol ol ol ol
cribes the actions of all three nurses?
ol ol ol ol ol o l
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are in
ol ol ol ol ol ol ol ol ol ol ol ol
volved with clinical pharmacology or pharmacotherapeutics, which is a bran
ol ol ol ol ol ol ol ol ol
ch of pharmacology that deals with the uses of drugs to treat, prevent, and di
ol ol ol ol ol ol ol ol ol ol ol ol ol ol
agnose disease. The radiology nurse is administering a drug to help diagnose
ol ol ol ol ol ol ol ol ol ol ol
a disease. The oncology nurse is administering a drug to help treat a disease.
ol ol ol ol ol ol ol ol ol ol ol ol ol ol ol
Pharmacoeconomics includes any costs involved in drug therapy. ol ol ol ol ol ol ol
Pharmacodynamics involves how a drug affects the body and pharmacokinetic ol ol ol ol ol ol ol ol ol
s is how the body acts on the body.
ol ol ol ol ol ol ol ol
2.
When involved in phase III drug evaluation studies, wh
ol ol ol ol ol ol ol ol
at responsibilities would the nurse have?
ol ol ol ol ol
A) Working with animals who are given experimental drugs
ol ol ol ol ol ol ol
B) Choosing appropriate patients to be involved in the drug study
ol ol ol ol ol ol ol ol ol
C) Monitoring and observing patients closely for adverse effects
ol ol ol ol ol ol ol
D) Conducting research to determine effectiveness of the drugol ol ol ol ol ol ol
, Page 3 of 822 ol ol ol
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
ol ol ol ol ol ol ol ol ol ol ol ol ol ol ol
patients are asked to record any symptoms they experience while taking the
ol ol ol ol ol ol ol ol ol ol ol ol
drugs. Nurses may be responsible for helping collect and analyze the inform
ol ol ol ol ol ol ol ol ol ol ol
ation to be shared with the Food and Drug Administration (FDA) but would
ol ol ol ol ol ol ol ol ol ol ol ol ol
not conduct research independently because nurses do not prescribe medicat
ol ol ol ol ol ol ol ol ol
ions. Use of animals in drug testing is done in the preclinical trials. Select p
ol ol ol ol ol ol ol ol ol ol ol ol ol ol
atients who are involved in phase II studies to participate in studies where th
ol ol ol ol ol ol ol ol ol ol ol ol ol
e participants have the disease the drug is intended to treat. These patients ar
ol ol ol ol ol ol ol ol ol ol ol ol ol
e monitored closely for drug action and adverse effects. Phase I studies invo
ol ol ol ol ol ol ol ol ol ol ol ol
lve healthy human volunteers who are usually paid for their participation. N
ol ol ol ol ol ol ol ol ol ol ol
urses may observe for adverse effects and toxicity.
ol ol ol ol ol ol ol
3.
A physician has ordered intramuscular (IM) injections of morphine, a nar
ol ol ol ol ol ol ol ol ol ol
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. Th
ol ol ol ol ol ol ol ol ol ol ol ol ol ol
e nurse is aware this drug has a high abuse potential. Under what category w
ol ol ol ol ol ol ol ol ol ol ol ol ol ol
ould morphine be classified?
ol ol ol
A) Schedule I ol
B) Schedule II ol
C) Schedule III ol
D) Schedule IV ol
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs be
ol ol ol ol ol ol ol ol ol ol ol ol
cause of severe dependence liability. Schedule I drugs have high abuse pot
ol ol ol ol ol ol ol ol ol ol ol
ential and no accepted medical use. Schedule III drugs have a lesser abuse
ol ol ol ol ol ol ol ol ol ol ol ol ol
potential than II and an accepted medical use. Schedule IV drugs have low a
ol ol ol ol ol ol ol ol ol ol ol ol ol
buse potential and limited dependence liability.
ol ol ol ol ol
4.
What concept is considered when generic drugs are substituted for bran
ol ol ol ol ol ol ol ol ol ol
d name drugs?
ol ol
A) Bioavailability
, WWW.THENURSINGMASTERY.
www.stuvia.com