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USABO Open Exam Questions w Complete Solutions (Latest 2025).

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USABO Open Exam Questions w Complete Solutions (Latest 2025).

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USABO Practice
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Uploaded on
March 22, 2025
Number of pages
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Written in
2024/2025
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USABO Open Exam Questions with
Complete Solutions (Latest 2025)
Both amino acids and nucleotides form complex chains.
Select all the answers below that are accurate.


A. The chains formed by both have polar phosphate groups.
B. Both contain peptide bonds.
C. Both contain nitrogen.
D. The chains formed by both can be lysed by trypsin.
E. The sequence of chains both form from preexisting
templates. - Correct Answers ✅C. Both contain nitrogen.
E. The sequence of chains both form from preexisting
templates.


When a population is in Hardy-Weinberg equilibrium, which of
the following is true?


A. All of its recessive lethal genes are wiped out, leaving only
healthy dominant genes.
B. dN/dt = 0, N = population size.
C. Mutations occur at five times the normal rate to balance
the loss of genes by way of natural selection.
D. The frequencies of the alleles in the population change
over time.
E. The frequencies of genotypes in the population are stable
over time. - Correct Answers ✅E. The frequencies of
genotypes in the population are stable over time.

,USABO Open Exam Questions with
Complete Solutions (Latest 2025)

Which of the following is NOT an accurate description of
protein synthesis and folding?


A. All protein synthesis is initiated in the cytoplasm.
B. Many copies of a protein can be synthesized
simultaneously from the same mRNA.
C. The 3D shape of a protein is determined largely by its
amino acid sequence.
D. The entire chain of amino acids exits the ribosome before
it begins folding into its 3D shape.
E. The first encoded amino acid in every protein is
methionine. - Correct Answers ✅C. The 3D shape of a
protein is determined largely by its amino acid sequence.


Neurotransmitter released at the synapse binds to two
classes of receptors. Select the correct response(s).


A. Metabotropic receptors that do not form an ion pore are
linked with signal transduction mechanisms and can alter
neuron function for seconds to minutes.
B. Receptor tyrosine kinases that activate signal transduction
mechanisms and change gene transcription that can last for
hours to days.

, USABO Open Exam Questions with
Complete Solutions (Latest 2025)
C. Ionotropic receptors that do not form an ion pore are linked
with signal transduction mechanisms and can alter neuron
function for seconds to minutes.
D. Ionotropic receptors that are directly linked to an ion pore
and are opened within milliseconds in response to
neurotransmitter.
E. Steroid hormone receptors that can activate changes in
gene transcription that can last for hours to days. - Correct
Answers ✅A. Metabotropic receptors that do not form an
ion pore are linked with signal transduction mechanisms and
can alter neuron function for seconds to minutes.
D. Ionotropic receptors that are directly linked to an ion pore
and are opened within milliseconds in response to
neurotransmitter.


Many proteins are transported around cells in vesicles. Which
of the following determines the specificity or directionality of
vesicle transport?


A. Clathrin coat proteins.
B. v-SNARES and t-SNARES.
C. Flippase.
D. Myristoylation.
E. Hydrophobic domains. - Correct Answers ✅B. v-SNARES
and t-SNARES.

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