Test Bank Understanding Pathophysiology 6th Edition
Chapter 01: Cellular Biology
rt rt rt
Huether & McCance: Understanding Pathophysiology, 6th Edition
rt rt rt rt rt rt
MULTIPLE CHOICES rt
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
with histones. Which of the following would also be observed by the student?
rt rt rt rt rt rt rt rt rt rt rt rt rt
a. A single circular chromosomert rt rt
b. A nucleus rt
c. Free-floating nuclear material rt rt
d. No organelles rt
ANS: B rt
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
nucleus; thus, the nucleus should be observed. A single circular chromosome called a
rt rt rt rt rt rt rt rt rt rt rt rt rt
rt prokaryote contains free-floating nuclear material but has no organelles.
rt rt rt rt rt rt rt rt
REF: p. 2 rt rt
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
a. Metabolic absorption rt
b. Communication
c. Secretion
d. Respiration
ANS: D rt
Test Bank Page 1
, Test Bank Understanding Pathophysiology 6th Edition
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
rt rt rt rt rt rt rt rt rt rt rt rt
rt secretion allows for the synthesizing of new substances.
rt rt rt rt rt rt rt
REF: p. 2 rt rt
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
the genetic information be contained?
rt rt rt rt rt
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm rt
ANS: C rt
The region of the cell that contains genetic material, including a large amount of ribonucleic
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
the cell’s nucleus. Mitochondria is associated with cellular respiration, while ribosomes are
rt rt rt rt rt rt rt rt rt rt rt rt
rt involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt cell.
REF: p. 2 rt rt
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
layer itself?
rt rt
a. Peripheral membrane proteins rt rt
b. Integral membrane proteins rt rt
c. Glycoproteins
d. Cell adhesion molecules rt rt
ANS: B rt
Proteins directly attached to the membrane bilayer can be removed by the action of integral
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
rt rt rt rt rt rt rt rt rt rt rt rt
rt surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
rt rt rt rt rt rt rt rt rt rt rt rt
rt marks cells and does not float.
rt rt rt rt rt
REF: p. 7 rt rt
5. Which of the following can bind to plasma membrane receptors?
rt rt rt rt rt rt rt rt rt
Test Bank Page 2
, Test Bank Understanding Pathophysiology 6th Edition
a. Oxygen
b. Ribosomes
c. Amphipathic lipids rt
d. Ligands
ANS: D rt
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
REF: p. 9 rt rt
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt pU
extracellular matrix would suN rtSthIeNdG
poR iaT
gnBo.
siC
s ofM
metastatic cancer?
rt rt rt rt rt
a. Decreased fibronectin rt
b. Increased collagen rt
c. Decreased elastin rt
d. Increased glycoproteins rt
ANS: A rt
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
them to travel or metastasize.
rt rt rt rt rt
REF: p. 10 rt rt
7. Which form of cell communication is used to relate to other cells in direct physical contact?
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
a. Cell junction rt
b. Gap junction rt
c. Desmosome
d. Tight junction rt
ANS: A rt
Cell junctions hold cells together and permit molecules to pass from cell to cell.
rt rt rt rt rt rt rt rt rt rt rt rt rt
Gap junctions allow for cellular communication between cells. Neither desmosomes nor tight
rt rt rt rt rt rt rt rt rt rt rt
junctions are associated with cellular communication.
rt rt rt rt rt rt
REF: p. 11 rt rt
Test Bank Page 3
, Test Bank Understanding Pathophysiology 6th Edition
8. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring
rt rt rt rt rt rt rt rt rt rt rt
alpha cells. This action is an example of which of the following signaling types?
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: A rt
Paracrine signaling involves the release of local chemical mediators that are quickly taken up,
rt rt rt rt rt rt rt rt rt rt rt rt rt
destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt glucagon. None of the other options involve signaling that is associated with a local chemical
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
mediator like insulin.
rt rt rt
REF: p. 12 rt rt
9. In cellular metabolism, each enzyme has a high affinity for a:
rt rt rt rt rt rt rt rt rt rt
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS: B rt
Each enzyme has a high affinity for a substrate, a specific substance converted to a product of
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
the reaction. Cellular metabolism is not dependent on an attraction between an enzyme and
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt any of the remaining options.
rt rt rt rt
REF: r t p. 16rt
Test Bank Page 4
Chapter 01: Cellular Biology
rt rt rt
Huether & McCance: Understanding Pathophysiology, 6th Edition
rt rt rt rt rt rt
MULTIPLE CHOICES rt
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
with histones. Which of the following would also be observed by the student?
rt rt rt rt rt rt rt rt rt rt rt rt rt
a. A single circular chromosomert rt rt
b. A nucleus rt
c. Free-floating nuclear material rt rt
d. No organelles rt
ANS: B rt
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
nucleus; thus, the nucleus should be observed. A single circular chromosome called a
rt rt rt rt rt rt rt rt rt rt rt rt rt
rt prokaryote contains free-floating nuclear material but has no organelles.
rt rt rt rt rt rt rt rt
REF: p. 2 rt rt
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
a. Metabolic absorption rt
b. Communication
c. Secretion
d. Respiration
ANS: D rt
Test Bank Page 1
, Test Bank Understanding Pathophysiology 6th Edition
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
rt rt rt rt rt rt rt rt rt rt rt rt
rt secretion allows for the synthesizing of new substances.
rt rt rt rt rt rt rt
REF: p. 2 rt rt
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
the genetic information be contained?
rt rt rt rt rt
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm rt
ANS: C rt
The region of the cell that contains genetic material, including a large amount of ribonucleic
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
the cell’s nucleus. Mitochondria is associated with cellular respiration, while ribosomes are
rt rt rt rt rt rt rt rt rt rt rt rt
rt involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt cell.
REF: p. 2 rt rt
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
layer itself?
rt rt
a. Peripheral membrane proteins rt rt
b. Integral membrane proteins rt rt
c. Glycoproteins
d. Cell adhesion molecules rt rt
ANS: B rt
Proteins directly attached to the membrane bilayer can be removed by the action of integral
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
rt rt rt rt rt rt rt rt rt rt rt rt
rt surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
rt rt rt rt rt rt rt rt rt rt rt rt
rt marks cells and does not float.
rt rt rt rt rt
REF: p. 7 rt rt
5. Which of the following can bind to plasma membrane receptors?
rt rt rt rt rt rt rt rt rt
Test Bank Page 2
, Test Bank Understanding Pathophysiology 6th Edition
a. Oxygen
b. Ribosomes
c. Amphipathic lipids rt
d. Ligands
ANS: D rt
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
REF: p. 9 rt rt
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt pU
extracellular matrix would suN rtSthIeNdG
poR iaT
gnBo.
siC
s ofM
metastatic cancer?
rt rt rt rt rt
a. Decreased fibronectin rt
b. Increased collagen rt
c. Decreased elastin rt
d. Increased glycoproteins rt
ANS: A rt
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
them to travel or metastasize.
rt rt rt rt rt
REF: p. 10 rt rt
7. Which form of cell communication is used to relate to other cells in direct physical contact?
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
a. Cell junction rt
b. Gap junction rt
c. Desmosome
d. Tight junction rt
ANS: A rt
Cell junctions hold cells together and permit molecules to pass from cell to cell.
rt rt rt rt rt rt rt rt rt rt rt rt rt
Gap junctions allow for cellular communication between cells. Neither desmosomes nor tight
rt rt rt rt rt rt rt rt rt rt rt
junctions are associated with cellular communication.
rt rt rt rt rt rt
REF: p. 11 rt rt
Test Bank Page 3
, Test Bank Understanding Pathophysiology 6th Edition
8. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring
rt rt rt rt rt rt rt rt rt rt rt
alpha cells. This action is an example of which of the following signaling types?
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: A rt
Paracrine signaling involves the release of local chemical mediators that are quickly taken up,
rt rt rt rt rt rt rt rt rt rt rt rt rt
destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt glucagon. None of the other options involve signaling that is associated with a local chemical
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
mediator like insulin.
rt rt rt
REF: p. 12 rt rt
9. In cellular metabolism, each enzyme has a high affinity for a:
rt rt rt rt rt rt rt rt rt rt
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS: B rt
Each enzyme has a high affinity for a substrate, a specific substance converted to a product of
rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt rt
the reaction. Cellular metabolism is not dependent on an attraction between an enzyme and
rt rt rt rt rt rt rt rt rt rt rt rt rt rt
rt any of the remaining options.
rt rt rt rt
REF: r t p. 16rt
Test Bank Page 4