PHM 321 Final Exam commonly Teste Questions
Verified Answers
Which of the following are found on all effector organs innervated by parasympathetic
postganglionic fibres
muscarinic receptors
Which of the following is associated with a decrease in cardiac conduction velocity?
muscarinic M2 receptors
Which of the following have an acetylcholinesterase inhibition effect on cholinergic
receptors?
pyridostigmine
Which of the following are non-depolarising nicotinic receptor antagonists?
D-tubocurare
Which of the following is a muscarinic receptor antagonist used in COPD treatment
ipratropium
Which of the following is a muscarinic receptor antagonist used in the treatment of
Parkinson's disease?
benztropine
All of the following are muscarinic receptor agonists except
succinylcholine
It is now understood that the mechanism of action of the majority of clinically active drugs is
mediated through binding to G-protein coupled receptors
True
The final active metabolite of norepinephrine is normetanephrine
, False
Contraction of the radial muscles of the iris is mediated through alpha1-selective receptor
activation
True
The final active metabolite of norepinephrine is VMA
True
Clondine is an
alpha2-slective adrenergic agonist
Which of the following cholinergic receptors is a g-coupled protein receptor?
Muscarinic
Which of the following cholinergic receptors is an ion channel
Nicotinic
All of the following are functions of muscarinic receptors except
It is a pentameric structure (2 alpha, one beta, gamma and sigma)
GABA receptors are mostly excitatory
False
Cl- ion influx
hyperpolarizes the cell
Acetylcholine receptors can be
both
Benzodiazapines affect
GABAa receptors
Verified Answers
Which of the following are found on all effector organs innervated by parasympathetic
postganglionic fibres
muscarinic receptors
Which of the following is associated with a decrease in cardiac conduction velocity?
muscarinic M2 receptors
Which of the following have an acetylcholinesterase inhibition effect on cholinergic
receptors?
pyridostigmine
Which of the following are non-depolarising nicotinic receptor antagonists?
D-tubocurare
Which of the following is a muscarinic receptor antagonist used in COPD treatment
ipratropium
Which of the following is a muscarinic receptor antagonist used in the treatment of
Parkinson's disease?
benztropine
All of the following are muscarinic receptor agonists except
succinylcholine
It is now understood that the mechanism of action of the majority of clinically active drugs is
mediated through binding to G-protein coupled receptors
True
The final active metabolite of norepinephrine is normetanephrine
, False
Contraction of the radial muscles of the iris is mediated through alpha1-selective receptor
activation
True
The final active metabolite of norepinephrine is VMA
True
Clondine is an
alpha2-slective adrenergic agonist
Which of the following cholinergic receptors is a g-coupled protein receptor?
Muscarinic
Which of the following cholinergic receptors is an ion channel
Nicotinic
All of the following are functions of muscarinic receptors except
It is a pentameric structure (2 alpha, one beta, gamma and sigma)
GABA receptors are mostly excitatory
False
Cl- ion influx
hyperpolarizes the cell
Acetylcholine receptors can be
both
Benzodiazapines affect
GABAa receptors
