NSG6005 Pharm Midterm exam
questions with correct answers
A patient's nutritional intake and lab work reflect hypoalbuminemia. This is critical to prescribing
because: - ✔✔Distribution of drugs to target tissue may be affected
Class IC drugs are reserved for what type of arrhythmia - ✔✔severe ventricular tachycardia
Class III drugs are effective in treating - ✔✔ventricular fibrillation
Half life of procainamide - ✔✔only short acting antiarrhythmic
antiarrhythmics are metabolized in the ____________ - ✔✔Liver
To treat or not to treat antiarrhythmic - ✔✔Antiarrhythmic drugs are understood to be
proarrhythmic, they can paradoxically correct one issue, but then cause another lethal arrhythmia.
Deciding not to treat may be a better choice, especially in asymptomatic or minimally symptomatic
patients
Drugs that have a significant first-pass effect: - ✔✔Are rapidly metabolized by the liver and may have
little if any desired action
The route of excretion of a volatile drug will be: - ✔✔The lungs
The point in time on the drug concentration curve that indicated the first sign of a therapeutic effect is
the: - ✔✔Onset of action
Factors that affect gastric drug absorption include: - ✔✔Lipid solubility of the drug
Which one of the following statements about bio availability is true? - ✔✔Bio availability issues are
especially important for drugs with narrow therapeutic ranges or sustained release mechanisms.
NSG 6005 Pharm Midterm exam questions with correct answers
,Steady State is: - ✔✔When the amount of drug in the body remains constant.
The time required for the amount of drug in the body to decrease by 50% is called: - ✔✔Half-life
An advantage of prescribing a sublingual medication is that the medication is: - ✔✔Absorbed rapidly
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 - ✔✔BOTH A and B
Induce the metabolism of another drug
Inhibit the metabolism of another drug
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because: - ✔✔A
six year old may have problems with swallowing a pill.
The first step in the prescribing process according to the world health organization is: - ✔✔diagnosing
the patient's problem D
Patient Education regarding prescribed medication includes: - ✔✔Discussion of expected ADRs
Pharmacokinetic factors that affect prescribing include - ✔✔Bioavalability
NSG 6005 Pharm Midterm exam questions with correct answers
, Infants and young children are at higher risk of ADRs due to - ✔✔Lack of safety and efficacy studies in
the pediatric population
The elderly are at high risk of ADRs due to: - ✔✔Age related decrease in renal function
The type of ADR that is the result of an unwanted but otherwise normal pharmacological action of a
drug given in the usual therapeutic doses is - ✔✔Type A
A patient may develop neutropenia from using typical Silvadene for burns. Neutropenia is: - ✔✔A
cytoxic hypersensitivity reaction
The ACE inhibitor Lisionpril is a known teratogen. Teratogens cause Type ______ ADR. - ✔✔D
A twenty year old male recieved multiple fractures in a motor vehichle accident that required
significant amounts of opioid medication to treat his pain. He is at risk for type ____ ADR when he no
longer requires the opioids. - ✔✔E
Which of the following factors may adversely affect a patients adherence to a therapeutic drug
regimen - ✔✔Both A and B
Non-adherence is especially common in drugs that treat asymptomatic conditions, such as
hypertension. One way to reduce the likelihood of nonadhereence to these drugs is to prescribe a
drug that: - ✔✔Has a tolerability profile with less of the adverse effects that are considered
"irritating" such as nausea and vomiting.
Patients with psychiatric illness have adherence rates to their drug regimen between 35-60%. To
improve adherence in this population, prescribe drugs: - ✔✔With a longer half life so that missed
doses produce a longer taper on the drug curve
Genetic polymorphisms account for differences in metabolism, including - ✔✔All of the above
Poor metabolizers that lack working enzymes
Intermediate metabolizers that have on working, wild-type allele and on mutant allele
NSG 6005 Pharm Midterm exam questions with correct answers
questions with correct answers
A patient's nutritional intake and lab work reflect hypoalbuminemia. This is critical to prescribing
because: - ✔✔Distribution of drugs to target tissue may be affected
Class IC drugs are reserved for what type of arrhythmia - ✔✔severe ventricular tachycardia
Class III drugs are effective in treating - ✔✔ventricular fibrillation
Half life of procainamide - ✔✔only short acting antiarrhythmic
antiarrhythmics are metabolized in the ____________ - ✔✔Liver
To treat or not to treat antiarrhythmic - ✔✔Antiarrhythmic drugs are understood to be
proarrhythmic, they can paradoxically correct one issue, but then cause another lethal arrhythmia.
Deciding not to treat may be a better choice, especially in asymptomatic or minimally symptomatic
patients
Drugs that have a significant first-pass effect: - ✔✔Are rapidly metabolized by the liver and may have
little if any desired action
The route of excretion of a volatile drug will be: - ✔✔The lungs
The point in time on the drug concentration curve that indicated the first sign of a therapeutic effect is
the: - ✔✔Onset of action
Factors that affect gastric drug absorption include: - ✔✔Lipid solubility of the drug
Which one of the following statements about bio availability is true? - ✔✔Bio availability issues are
especially important for drugs with narrow therapeutic ranges or sustained release mechanisms.
NSG 6005 Pharm Midterm exam questions with correct answers
,Steady State is: - ✔✔When the amount of drug in the body remains constant.
The time required for the amount of drug in the body to decrease by 50% is called: - ✔✔Half-life
An advantage of prescribing a sublingual medication is that the medication is: - ✔✔Absorbed rapidly
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 - ✔✔BOTH A and B
Induce the metabolism of another drug
Inhibit the metabolism of another drug
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because: - ✔✔A
six year old may have problems with swallowing a pill.
The first step in the prescribing process according to the world health organization is: - ✔✔diagnosing
the patient's problem D
Patient Education regarding prescribed medication includes: - ✔✔Discussion of expected ADRs
Pharmacokinetic factors that affect prescribing include - ✔✔Bioavalability
NSG 6005 Pharm Midterm exam questions with correct answers
, Infants and young children are at higher risk of ADRs due to - ✔✔Lack of safety and efficacy studies in
the pediatric population
The elderly are at high risk of ADRs due to: - ✔✔Age related decrease in renal function
The type of ADR that is the result of an unwanted but otherwise normal pharmacological action of a
drug given in the usual therapeutic doses is - ✔✔Type A
A patient may develop neutropenia from using typical Silvadene for burns. Neutropenia is: - ✔✔A
cytoxic hypersensitivity reaction
The ACE inhibitor Lisionpril is a known teratogen. Teratogens cause Type ______ ADR. - ✔✔D
A twenty year old male recieved multiple fractures in a motor vehichle accident that required
significant amounts of opioid medication to treat his pain. He is at risk for type ____ ADR when he no
longer requires the opioids. - ✔✔E
Which of the following factors may adversely affect a patients adherence to a therapeutic drug
regimen - ✔✔Both A and B
Non-adherence is especially common in drugs that treat asymptomatic conditions, such as
hypertension. One way to reduce the likelihood of nonadhereence to these drugs is to prescribe a
drug that: - ✔✔Has a tolerability profile with less of the adverse effects that are considered
"irritating" such as nausea and vomiting.
Patients with psychiatric illness have adherence rates to their drug regimen between 35-60%. To
improve adherence in this population, prescribe drugs: - ✔✔With a longer half life so that missed
doses produce a longer taper on the drug curve
Genetic polymorphisms account for differences in metabolism, including - ✔✔All of the above
Poor metabolizers that lack working enzymes
Intermediate metabolizers that have on working, wild-type allele and on mutant allele
NSG 6005 Pharm Midterm exam questions with correct answers
