HEMA MOCK BOARDS
In the bone marrow, erythroid precursors are
located:
A Surrounding macrophages in erythroid
islands
B Adjacent to megakaryocytes along the adventitial
cell
C lining
Surrounding fat cells in apoptotic
islands
D In the center of the hematopoietic cords correct answers A
Surrounding
macrophages in erythroid
islands
Which of the following are characteristics of pluripotential hematopoietic
stem cells?
Possess I.
self-renewal ability II. Produces progenitor cells committed to a
particular
lineage III.cell
Morphologically unrecognizable IV. Expression of CD34 V.
Expression of
CD3
8
A.
IandII
B.
IandIV
C. I, II, III, and
IV
D. I, II, III, IV, and V correct answers D. I, II, III, IV,
and V
Which of the following statements characterize erythropoietin (EPO)
function? I. the CFU-E into the earliest recognizable RBC precursor II.
Transforms
Increases
rate of redthe blood cell production by the bone marrow III. Shortens the
maturation erythroid
developing time of precursors IV. Decreases stimulation of
erythropoiesis
cellular hypoxiawhen
increases
A. I and
II
B. I, II, and
C. II and
III
III
D. I, II, III, and IV correct answers B. I, II,
and III
All of these are correct,
except:
A. The kidneys recognize the tissue hypoxia through the peritubular
cells of the
interstitiu
B. Tissue hypoxia is a prime stimulant for erythropoietin
m.
production.
C. Apoptosis is a physiologic process and its inhibition may
also
D. occur.
Erythropoietin acts mainly on pronormoblast. correct answers D.
Erythropoietin
mainly on acts
pronormoblast.
Which of the following factors will result in an increase in oxygen delivery to
the
I. tissues? blood pH II. High altitudes III. Increased hemoglobin binding of
Increased
2,3-BPG
IV. Increased compensatory Hemoglobin F V. Increased carbon
dioxide
A. I, II, III, and
IV
B. II and
III
,C. II, III, and
V
D. I, II, III, and V correct answers C. II, III,
and V
True for Sulfhemoglobinemia. Select all that apply. I. Reversible
oxidation of II. reported upon exposure to sulfur drugs e.g. sulfanilamide III.
hemoglobin
Reportedwith
patients in severe constipation in cases of severe bacteremia due to
Clostridium
perfringens IV. Can be measured using Cyanmethemoglobin method V.
gives blood
mauve a
lavender
discoloration
A. II and
V
B. II and
III
C. I, II, and
III
D. II, III, and V correct answers D. II, III,
and V
The EMP net gain of 2 ATP provides high energy phosphates to all of the
following
EXCEPT:
A. Maintenance of membrane
lipids
B. Power that cation pump needed for Na-K concentration pump
and
C. Ca flux the shape and flexibility of the cellular
Preserve
membrane
D. Gas exchange between the lungs and blood correct answers D. Gas
exchange
between the lungs and
blood
What is the percent transferrin saturation for a patient with total serum iron
of 63TIBC
and mg/dL of 420
mg/dL?
A.
0.15%
B.
1.2%
C.
12%
D.
15%
E. 80% correct answers D.
15%
A 56-year-old man was admitted to the hospital for treatment of a bleeding
ulcer. Thelaboratory data were obtained: RBC 4.2 x 10*8/ul, WBC 5.0 x
following
10*8/ul,
30%, Hgb Hct8.5 g/dl, serum iron 40 ug/dl, TIBC 460 ug/dl, serum ferritin
12 ng/ml.
Examination of the bone marrow revealed the absence of iron stores. This
data is most
consistent with which of the following
conditions?
a. iron deficiency
b. anemia of chronic
anemia
disease
c.
hemochromatosis
d. acute blood loss correct answers a. iron deficiency
anemia
A 32-year-old African-American traveling to Africa on business had been
healthy
he began until
taking primaquine for prevention of malaria. He went to his
physician
he felt faint because
and his urine was black. His CBC results are as follows: WBC
6.5 XX109/L
(6.5 103/^L); RBC 1.67 X 1012/L (1.67 x 1 O%L|_); hemoglobin level
50 g/L hematocrit
g/dL); (5.0 0.15 L7L (15%); MCV 89.8 fL; MCHC 33.3 g/dL; platelet
count 175
109/L x
(175,000/|jiL); reticulocyte25.0%. The defect in this disorder is
caused by an
, A. Amino acid
substitution
B. Intrinsic red blood cell membrane
defect
C. Enzyme deficiency in the hexose
monophosphate
D. shuntin the Embden-Meyerhof pathway correct answers
Enzyme deficiency
C. Enzyme in the hexose monophosphate
deficiency
shunt
Which of the following disorders is not classified as a microangiopathic
hemolytic
anemia
?
A. Disseminated intravascular
coagulation
B. Hemolytic uremic
syndrome
C. Traumatic cardiac hemolytic
anemia
D. Thrombotic thrombocytopenic purpura correct answers C.
Traumatic cardiac
hemolytic
anemia
What is the total WBC count if blood is drawn to the 0.5 mark and diluted
to the and
mark, 11.0100 cells are counted in 4 corner squares of the improved
Neubauer
hemocytomete
r?
A 2.5 x
10^9/L
B 4.4 x
10^9/L
C 5.0 x
10^9/L
D 8.0 x 10^9/L correct answers C 5.0 x
10^9/L
If an average of 3 WBCs were observed per field using a 40x high-dry
objective,
WBC the
estimate
is:
A 3,000μL or 3 x
109L
B 6,000μL or 6 x
109L
C 9,000μL or 9 x
109L
D 12,000μL or 12 x 109L correct answers B 6,000μL or 6 x
109L
In an adult, what are the two best areas for obtaining active bone marrow by
aspiration?
A Vertebra,
tibia
B Sternum,
vertebra
C Anterior iliac crest,
tibia
D Posterior iliac crest, sternum correct answers D Posterior iliac crest,
sternum
Lipemia can cause turbidity in the cyanmethemoglobin method and a
falsely high result. It can be
hemoglobin
corrected by:
A Reagent-sample solution can be centrifuged and supernatant
measured
B Adding 0.01mL of the patient's plasma to 5mL of the cyanmethemoglobin
reagent
using and
this solution as reagent
blank
C Making a 1:2 dilution with distilled water (1 part diluted sample plus 1 part
water) and the results from the standard
multiplying
curve
D by 2be corrected correct answers B Adding 0.01mL of the patient's
Cannot
plasma
5mL to cyanmethemoglobin reagent and using this solution as
of the
reagent blank
In the bone marrow, erythroid precursors are
located:
A Surrounding macrophages in erythroid
islands
B Adjacent to megakaryocytes along the adventitial
cell
C lining
Surrounding fat cells in apoptotic
islands
D In the center of the hematopoietic cords correct answers A
Surrounding
macrophages in erythroid
islands
Which of the following are characteristics of pluripotential hematopoietic
stem cells?
Possess I.
self-renewal ability II. Produces progenitor cells committed to a
particular
lineage III.cell
Morphologically unrecognizable IV. Expression of CD34 V.
Expression of
CD3
8
A.
IandII
B.
IandIV
C. I, II, III, and
IV
D. I, II, III, IV, and V correct answers D. I, II, III, IV,
and V
Which of the following statements characterize erythropoietin (EPO)
function? I. the CFU-E into the earliest recognizable RBC precursor II.
Transforms
Increases
rate of redthe blood cell production by the bone marrow III. Shortens the
maturation erythroid
developing time of precursors IV. Decreases stimulation of
erythropoiesis
cellular hypoxiawhen
increases
A. I and
II
B. I, II, and
C. II and
III
III
D. I, II, III, and IV correct answers B. I, II,
and III
All of these are correct,
except:
A. The kidneys recognize the tissue hypoxia through the peritubular
cells of the
interstitiu
B. Tissue hypoxia is a prime stimulant for erythropoietin
m.
production.
C. Apoptosis is a physiologic process and its inhibition may
also
D. occur.
Erythropoietin acts mainly on pronormoblast. correct answers D.
Erythropoietin
mainly on acts
pronormoblast.
Which of the following factors will result in an increase in oxygen delivery to
the
I. tissues? blood pH II. High altitudes III. Increased hemoglobin binding of
Increased
2,3-BPG
IV. Increased compensatory Hemoglobin F V. Increased carbon
dioxide
A. I, II, III, and
IV
B. II and
III
,C. II, III, and
V
D. I, II, III, and V correct answers C. II, III,
and V
True for Sulfhemoglobinemia. Select all that apply. I. Reversible
oxidation of II. reported upon exposure to sulfur drugs e.g. sulfanilamide III.
hemoglobin
Reportedwith
patients in severe constipation in cases of severe bacteremia due to
Clostridium
perfringens IV. Can be measured using Cyanmethemoglobin method V.
gives blood
mauve a
lavender
discoloration
A. II and
V
B. II and
III
C. I, II, and
III
D. II, III, and V correct answers D. II, III,
and V
The EMP net gain of 2 ATP provides high energy phosphates to all of the
following
EXCEPT:
A. Maintenance of membrane
lipids
B. Power that cation pump needed for Na-K concentration pump
and
C. Ca flux the shape and flexibility of the cellular
Preserve
membrane
D. Gas exchange between the lungs and blood correct answers D. Gas
exchange
between the lungs and
blood
What is the percent transferrin saturation for a patient with total serum iron
of 63TIBC
and mg/dL of 420
mg/dL?
A.
0.15%
B.
1.2%
C.
12%
D.
15%
E. 80% correct answers D.
15%
A 56-year-old man was admitted to the hospital for treatment of a bleeding
ulcer. Thelaboratory data were obtained: RBC 4.2 x 10*8/ul, WBC 5.0 x
following
10*8/ul,
30%, Hgb Hct8.5 g/dl, serum iron 40 ug/dl, TIBC 460 ug/dl, serum ferritin
12 ng/ml.
Examination of the bone marrow revealed the absence of iron stores. This
data is most
consistent with which of the following
conditions?
a. iron deficiency
b. anemia of chronic
anemia
disease
c.
hemochromatosis
d. acute blood loss correct answers a. iron deficiency
anemia
A 32-year-old African-American traveling to Africa on business had been
healthy
he began until
taking primaquine for prevention of malaria. He went to his
physician
he felt faint because
and his urine was black. His CBC results are as follows: WBC
6.5 XX109/L
(6.5 103/^L); RBC 1.67 X 1012/L (1.67 x 1 O%L|_); hemoglobin level
50 g/L hematocrit
g/dL); (5.0 0.15 L7L (15%); MCV 89.8 fL; MCHC 33.3 g/dL; platelet
count 175
109/L x
(175,000/|jiL); reticulocyte25.0%. The defect in this disorder is
caused by an
, A. Amino acid
substitution
B. Intrinsic red blood cell membrane
defect
C. Enzyme deficiency in the hexose
monophosphate
D. shuntin the Embden-Meyerhof pathway correct answers
Enzyme deficiency
C. Enzyme in the hexose monophosphate
deficiency
shunt
Which of the following disorders is not classified as a microangiopathic
hemolytic
anemia
?
A. Disseminated intravascular
coagulation
B. Hemolytic uremic
syndrome
C. Traumatic cardiac hemolytic
anemia
D. Thrombotic thrombocytopenic purpura correct answers C.
Traumatic cardiac
hemolytic
anemia
What is the total WBC count if blood is drawn to the 0.5 mark and diluted
to the and
mark, 11.0100 cells are counted in 4 corner squares of the improved
Neubauer
hemocytomete
r?
A 2.5 x
10^9/L
B 4.4 x
10^9/L
C 5.0 x
10^9/L
D 8.0 x 10^9/L correct answers C 5.0 x
10^9/L
If an average of 3 WBCs were observed per field using a 40x high-dry
objective,
WBC the
estimate
is:
A 3,000μL or 3 x
109L
B 6,000μL or 6 x
109L
C 9,000μL or 9 x
109L
D 12,000μL or 12 x 109L correct answers B 6,000μL or 6 x
109L
In an adult, what are the two best areas for obtaining active bone marrow by
aspiration?
A Vertebra,
tibia
B Sternum,
vertebra
C Anterior iliac crest,
tibia
D Posterior iliac crest, sternum correct answers D Posterior iliac crest,
sternum
Lipemia can cause turbidity in the cyanmethemoglobin method and a
falsely high result. It can be
hemoglobin
corrected by:
A Reagent-sample solution can be centrifuged and supernatant
measured
B Adding 0.01mL of the patient's plasma to 5mL of the cyanmethemoglobin
reagent
using and
this solution as reagent
blank
C Making a 1:2 dilution with distilled water (1 part diluted sample plus 1 part
water) and the results from the standard
multiplying
curve
D by 2be corrected correct answers B Adding 0.01mL of the patient's
Cannot
plasma
5mL to cyanmethemoglobin reagent and using this solution as
of the
reagent blank
