NSG5003 Week 2 Quiz With Complete
Solution A+ Graded
Hypersensitivity is best defined as a(an) - ANSWER c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - ANSWER
Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins? - ANSWER IgE
Which type of antibody is involved in type I hypersensitivity reaction? - ANSWER IgE
Blood transfusion reactions are a form of: - ANSWER Alloimmunity
Which leukocyte is activated in an IgE-mediated hypersensitivity reaction? - ANSWER c.
Eosinophils
The degranulation of mast cells in IgE-mediated hypersensitivity is caused by the action
of which of the following receptors? - ANSWER Histamine bound to H2
Atopic individuals are genetically predisposed to develop allergies because they have: -
ANSWER c.
More IgE
What is the mechanism that results in type II hypersensitivity reactions? - ANSWER d.
,Antibodies bind to the antigens on the cell surface.
When mismatched blood is given that causes ABO incompatibility, the erythrocytes are
lysed by - ANSWER a.
Complement-mediated cell lysis
When antibodies form against red blood cell antigens of the Rh system, the blood cells
are lysed by: - ANSWER Phagocytosis in the spleen
When the soluble antigens from infectious agents enter circulation, tissue damage
results from: - ANSWER d.
Neutrophil granules and toxic oxygen products
Target cell destruction in a type II hypersensitivity reaction occurs via the action of: -
ANSWER d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity
reaction? - ANSWER Modulation
Type III hypersensitivity reactions are the result of which of the following? - ANSWER b.
Binding of antibodies to soluble antigens that were released into body fluids and
deposition of the immune complexes in the tissues
A type IV hypersensitivity reaction causes which result? - ANSWER .
The lymphokine-producing Th1 cells directly attack and destroy cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes
that are deposited in tissues are a result of: - ANSWER Complement activation
, Raynaud phenomenon is a form of type III hypersensitivity reaction and is caused by: -
ANSWER a.
Immune complexes that are deposited in capillary beds, obstructing circulation
Deficiency of which of the following metals can lead to depression in function of both B
and T cells? - ANSWER Zinc
Sensitization of the maternal immune system against antigens expressed by the fetus is
an example of what type of reaction? - ANSWER Alloimmunity
Which disease results from the deposition of circulating immune complexes containing
an antibody against the host DNA in tissues? - ANS Systemic lupus erythematosus
Why does there occur a tissue damage in acute rejection following organ
transplantation? - ANS a.
Th1 cells secrete cytokines that activate the infiltrating macrophages; cytotoxic T cells
attack the endothelial cells directly in the transplanted tissue.
What type of blood cell would carry the carbohydrate antigens for blood type? -
ANSwER Erythrocytes
A person with blood type O would most likely have high titers of what anti-antibodies? -
ANSwER A and B
What class of immunoglobulins forms isohemagglutinins? - ANSwER IgM
An individual infected with a virus, fungus, or yeast would most likely lack or have
defective what immunological component? - ANSwER T cells
What is the primary immune deficiency in which T-cell immunity is partially or
completely absent? DiGeorge syndrome
Solution A+ Graded
Hypersensitivity is best defined as a(an) - ANSWER c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - ANSWER
Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins? - ANSWER IgE
Which type of antibody is involved in type I hypersensitivity reaction? - ANSWER IgE
Blood transfusion reactions are a form of: - ANSWER Alloimmunity
Which leukocyte is activated in an IgE-mediated hypersensitivity reaction? - ANSWER c.
Eosinophils
The degranulation of mast cells in IgE-mediated hypersensitivity is caused by the action
of which of the following receptors? - ANSWER Histamine bound to H2
Atopic individuals are genetically predisposed to develop allergies because they have: -
ANSWER c.
More IgE
What is the mechanism that results in type II hypersensitivity reactions? - ANSWER d.
,Antibodies bind to the antigens on the cell surface.
When mismatched blood is given that causes ABO incompatibility, the erythrocytes are
lysed by - ANSWER a.
Complement-mediated cell lysis
When antibodies form against red blood cell antigens of the Rh system, the blood cells
are lysed by: - ANSWER Phagocytosis in the spleen
When the soluble antigens from infectious agents enter circulation, tissue damage
results from: - ANSWER d.
Neutrophil granules and toxic oxygen products
Target cell destruction in a type II hypersensitivity reaction occurs via the action of: -
ANSWER d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity
reaction? - ANSWER Modulation
Type III hypersensitivity reactions are the result of which of the following? - ANSWER b.
Binding of antibodies to soluble antigens that were released into body fluids and
deposition of the immune complexes in the tissues
A type IV hypersensitivity reaction causes which result? - ANSWER .
The lymphokine-producing Th1 cells directly attack and destroy cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes
that are deposited in tissues are a result of: - ANSWER Complement activation
, Raynaud phenomenon is a form of type III hypersensitivity reaction and is caused by: -
ANSWER a.
Immune complexes that are deposited in capillary beds, obstructing circulation
Deficiency of which of the following metals can lead to depression in function of both B
and T cells? - ANSWER Zinc
Sensitization of the maternal immune system against antigens expressed by the fetus is
an example of what type of reaction? - ANSWER Alloimmunity
Which disease results from the deposition of circulating immune complexes containing
an antibody against the host DNA in tissues? - ANS Systemic lupus erythematosus
Why does there occur a tissue damage in acute rejection following organ
transplantation? - ANS a.
Th1 cells secrete cytokines that activate the infiltrating macrophages; cytotoxic T cells
attack the endothelial cells directly in the transplanted tissue.
What type of blood cell would carry the carbohydrate antigens for blood type? -
ANSwER Erythrocytes
A person with blood type O would most likely have high titers of what anti-antibodies? -
ANSwER A and B
What class of immunoglobulins forms isohemagglutinins? - ANSwER IgM
An individual infected with a virus, fungus, or yeast would most likely lack or have
defective what immunological component? - ANSwER T cells
What is the primary immune deficiency in which T-cell immunity is partially or
completely absent? DiGeorge syndrome
