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, What is the mechanism of action of theophylline for asthma anti-inflammatory and immunodilator
properties which enhance mucociliary clearance and strengthen diaphragmatic contractility.
Why are drug levels of Theophylline monitored? Due to narrow therapeutic ranges.
Name the leukotriene modifiers for asthma Zileutonn, zafirlukast, montelukast
use of leukotriene modifiers for asthma? alternatives to low-dose inhaled corticosteroids in pt.
w/mild persistent asthma
*as mono-therapy are usually less effective than inhaled corticosteroids
Which recombinant antibody that binds IgE w/o activating mast cells can be used to treat SEVERE
asthma in 18 yr old and older Omalizumab and Reslizumab
Which vaccinations should the FNP ensure that a pt with asthma receives? pneumovac and
influenze
Which patients are oral sustained release beta 2 agonist be reserved for? pt. with nocturnal
asthma or persistent mod-severe asthma who do not respond to other therapies.
A patient has a PEF> 80% and minor changes in airway function. What severity of asthma exacerbation
does this patient have? Mild asthma exacerbation
The FNP should double the dose of inhaled corticosteroids during an asthma exacerbation, true or false?
False.
Doubling the dose of the inhaled corticosteroid is not effective and not recommended.
A patient is experiencing mild asthma exacerbation and currently not taking an inhaled corticosteroid,
what can the FNP do? initiate one
The FNP expects many pts with mild asthma exacerbation to respond fully and quickly to which
treatment? Inhaled SABA
Can the FNP start an oral corticosteroid if the patient is already taking an inhaled corticosteroid? Yes
What is the goal of treating moderate asthma exacerbation? **Correct hypoxemia!
Reverse airflow obstruction
reduce likelihood of reoccurrence of obstruction
What should the FNP prescribe to correct hypoxemia in a pt with exacerbation of asthma
Oxygen!
When should systemic corticosteroids be given to a pt with asthma exacerbation When peak
flow is <70% of baseline
To pt. who doesn't respond to several SABA treatments
What criteria correlates to the severity of asthma exacerbation? Improvement of FEVI after 30 minutes