NR 566 MIDTERM 3 LATEST UPDATE WITH
INSIGHTFUL QUESTIONS, ANSWERED CORRECTLY
|A+ GRADE ASSURED|
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk? ANS ✔ -Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? ANS ✔ --
Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? ANS ✔ -3 months or less
What drug schedule are Phentermine and Diethylpropion under? ANS ✔ -
Schedule IV ASCORERS STUVIA
What labs should be monitored with Phentermine and Diethylpropion? What condition should we screen for? ANS ✔ --baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects ANS ✔ --increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? ANS ✔ -Increases satiety
What are some Phentermine/topiramate contraindications for use? ANS ✔
-not approved in children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia? ANS ✔ -given before 1600 ASCORERS STUVIA
What are some high-risk patient conditions that we should use Phentermine/topiramate with caution? ANS ✔ -hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects ANS ✔ -insomnia, nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing phentermine/topiramate? Select all that apply. ANS ✔ -A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D ASCORERS STUVIA
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%. ANS ✔ -GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be absorbed well when taking Orlistat. ANS ✔ -2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. ANS ✔ -12
Orlistat results in the least amount of weight loss of all. How much? ANS ✔
-2-3% body weight (7 lbs in year)
Orlistat adverse effects ANS ✔ -Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? ANS ✔ -In those with malabsorption syndrome or cholestasis