7THEDITIONKOEPPENALLCHAPTERS1-44
COMPLETEGUIDE(NEWESTVERSION)2024. BerneandLevyPhysiology7thEditionKoeppen
NBerneandLevyPhysiology7thEditionKoeppenTestBank
Koeppen:BerneandLevyPhysiology,7thEdition
Chapter01:PrinciplesofCell
FunctionTestBank
MultipleChoice
1.Thesubcellularstructurethatdegradesproteinsiscalledthe:
A.Tightjunction
B.Mitochondria
C.Lysosome
D.Plasmamembrane
E.Ribosome
ANS:C
2.Anexperimentisdonetomeasuretheuptakeofanaminoacidintoacell.Thefollowing
dataareobtained:
IfNa+isremovedfromtheextracellularbathingsolution,orifadrugisaddedthatpreventsthe
cellfrommakingadenosinetriphosphate(ATP),theuptakeofaminoacidintothecellis
markedlyreduced.Accordingtothisinformation,whichofthefollowingmechanismsis
probablyresponsibleforthetransportoftheaminoacidintothecell?
A.Passivediffusionthroughthelipidbilayer
B.Uniporter
C.TransportATPase
D.Na+symporter
E.Na+antiporter
ANS:D
3.AmembranepermeablebyonlyNa+separatestwocompartmentscontaining
Na2SO4,shownasfollows: BerneandLevyPhysiology7thEditionKoeppen
USNT
Electrodesareplacedinbothcompartments,andavoltageisapplied(thatofcompartmentAis
heldat0mV).WhatvoltageappliedtocompartmentBwouldresultinnonetmovementofNa+
acrossthemembraneseparatingthecompartments?
A.–60mV
B.–30mV
C.0mV
D.+30mV
E.+60mV
ANS:E
4.TherestingmembranepotentNialoRfaIcellGis–B85.mCV.Theintracellularandextracellular
concentrationsofseveralionsareindicatedinthefollowingtable,asisthecalculated
Nernstequilibriumpotential(Ei)foreachoftheseions:
Ion Concentration
InsideCellConcentration
OutsideCellEi
Na+12mEq/L 145mEq/L 66mV
K+ 150mEq/L 4mEq/L –96mV
Cl–30mEq/L 105mEq/L –33mV
Ca++ 0.0001mmol/dL1mmol/dL 122mV
ThemembranehaschannelsforNa+,K+,Cl–,andCa++.Theconductanceofthe
membraneisthegreatestforwhichion?
A.Na+
B.K+
C.Cl–
D.Ca++
ANS:B
5.Acellcontainsthefollowingmembranetransporters:
Na+channelK+channel
Na+,K+-ATPase
Therestingmembranevoltageofthecellis–80mV,andtheintracellularand BerneandLevyPhysiology7thEditionKoeppen
extracellularionconcentrationsareasfollows:
IonIntracellular
ConcentrationExtracellular
Concentration
Na+10mEq/L 145mEq/L
K+ 120mEq/L 4mEq/L
ThecellistreatedwithadrugtoinhibittheNa+,K+-ATPase.Whatwouldbetheeffectofthisdrug
onthefollowingparameters?
Intracellular[Na+]Intracellular[K+]CellVolumeMembraneVoltage
A.Decrease Decrease DecreaseDepolarize
B.Increase Decrease Increase Depolarize
C.Increase Increase Increase Nochange
D.Decrease Increase DecreaseHyperpolarize
E.Increase Increase DecreaseHyperpolarize
ANS:B
6.Whichofthelabeledproteins(shaded)isattachedtothemembranebya
glycosylphosphatidylinositol(GPI)anchor?
ANS:E
7.AcellhaschannelsforNa+,K+,andCl–initsplasmamembrane.Therestingmembrane
potentialis–60mV(cellinteriornegative).Theintracellularandextracellular
concentrationsfortheseions,aswellasthecalculatedNernstpotentials,arelistedas
follows: