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Samenvatting Uitwerking neurologie neonaat

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Uitgebreide uitwerking van de neurologie bij een neonaat

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Uploaded on
June 13, 2017
Number of pages
2
Written in
2016/2017
Type
Summary

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OG Neurologie

Periventriculaire leukomalacie
Oorzaken PVL
- Hypoperfusie hersenen
o Hypotensie
o Hypocapnie
- Infectie
- Sepsis
- Open ductus

Ziekten die kunnen leiden tot PVL
- Solutio
- Asfyxie
- Sepsis
- Nec
- Frequentie apneu’s

Autoregulatie
- RR stijgt, dan gaat cerebrale bloedflow omhoog.
- Bij prematuren niet goed ontwikkeld
- Hoe lager de PCO2, hoe minder de cerebrale bloedflow.
- Hoe hoger de PCO2, hoe hoger de cerebrale bloedflow.

Gevolgen PVL
Motorisch:
- 75% ernstige schade
- 15% nergens last van
- 10% milde stoornis
Mentaal:
- 25% geen schade
- 40% ernstige schade
Visus
- 50% geen schade
- 30% strabismus

Preventie PVL:
- Voorkomen hypotensie
- Voorkomen hypocapnie
- Voorkomen Infecties

Hersenbloedingen
Oorzaak
- Fragiele capillairen in germinatieve laag
- Toename cbf
- Fluctuaties cbf
- Toename veneuze druk: met hogere druk beademen is ook een toename van
de veneuze druk.

- Lage PaO2 geeft een hele hoge cerebrale bloedflow
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