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The Structure of Life on Earth

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This document is an overview of: - The Structure of Life: Building Blocks – Amino Acids - The Structure of Life: Cells - The Structure of Life: DNA - DNA Replication - Cellular Energy

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November 21, 2022
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2022/2023
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Charles cockell
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Astrobiology and the Search for Extra Terrestrial Life

The University of Edinburgh

Lecture Summary: The Structure of Life



The Structure of Life: Building Blocks
The fundamental elements that make up most of the compounds from which life is constructed:

- Carbon
- Hydrogen
- Nitrogen
- Oxygen
- Phosphorus
- Sulphur

Other elements:
- Iron
→ Red blood cells
- Calcium
→ Forms phosphate structures that are part of all skeletons


Example: Glycine

- An amino acid
- Made up of 2 carbon atoms, nitrogen,
some hydrogen and oxygen
→ Also conforms to the idea of
CHNOPS
- Carbon is the backbone of the molecule




About Amino Acids
- Amino acids linked in a long chain makes up a protein
- Can bind to other chains
- Can fold up in particular shapes
- Forms the complex diversity of complex molecules that make up life
- Amino acids are essential as building blocks for constructing the proteins in our cells

, Life needs other molecules as well, like sugars and water.

About Sugar

- Has ring-like structure called adenine
- Fine carbons form the ring around an
oxygen atom
- Various other atoms attach to that ring of
carbon atoms
- Can be strung together to create long,
complex chains of sugars
→ This is how we end up with complex
carbohydrates in our food



About Adenine
- Can be transformed by adding a reverse sugar structure to make adenosine

About Adenosine
- Can add phosphorus and oxygen atoms
- Oxygen atoms gives phosphate molecules as phosphate groups
- This creates adenosine triphosphate

About Adenosine Triphosphate
- Forms a component of deoxyribonucleic acid (DNA) IF strung together with other
molecules



These biosynthesis reactions occur within the cells of all organisms on Earth.




Water
- Water is the solvent in which these chemical reactions can occur
→ We need a liquid in order for molecules to move around




We refer to life on Earth as being carbon-based and water-based because the molecules
from which humans are constructed have carbon as their backbone, and water is required
in order for the necessary chemical reactions to occur within our cells.
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