NR-507 IStudy IGuide
1. Types Iof Iimmunity Ich I7 I& I8
a. Innate- Inatural Iepithelial Ibarrier Iand Iinflammation Ithe Imake Iinnate Iresistance Iand
Iprotection Ipg. I191
b. Adaptive/ Iacquired- Iimmune Iresponse Ior Iimmunity, Iafter Iinnate Iand Iinflammation,
i. Active I(Acquired) I-after Inatural Iexposure Ito Ian Iantigen Ior Iafter Iimmunization Ipg.
I227
ii. Passive I(Acquired)- Ipreformed Iantibodies Ior It Ilymphocytes Iare Itransferred Irom Ia
donor Ito Ithe Irecipient, Imaternal Ito Ifetus, Ior Ibone Imarrow Itransplant Ipg. I227
2. Alveolar Iventilation/perfusion- Ipg. I1239 ICh I34
a. Ratio Ibetween Ithe Iamount Iof Iair Igetting Iinto Ithe Ialveoli Iand Ithe Iamount Iof Iblood Ibeing
Isent Ito Ithe Ilungs.
3. Dermatologic Iconditions I ch. I46 Ie.g. Ipityriasis Irosea- Ibenign Iself-limiting Iinflammatory Idisorder
that Ioccurs Iin Iyoung Iadults, Iwith Iseasonal Ipeaks Ispring Iand Ifall. IHarmful Iin Ipregnancy.
IAssociated Iwith Ia Ivirus, Istarts Iwith Ia Iherald Ipatch, Icircular. ISalmon Ipink, Iand Idemarcated, Iusually
Ion Ithe Itrunk, Iacyclovir Iand Ierythromycin, Iand Icorticosteroid Icreams Ifor Iitching. IShould Igo Iaway
Iwithin Ia Ifew Imonths.
4. Croup- Ipg. I1294-1296 IViral, Ibarking Icough, Iwinter Iand Ispring Imonths, Iusually Iaffects Ichildren I6
mo Ito I3 Iyrs, Ipeak Iat I2 Iyears Iold, Istridor, Iand Ifever, I2-5 Idays. Ihuman Iparainfluenza Iviruses I(HPIVs),
IRSV, I viruses Iare Iairborne. IRest, Ihumidity, Iand Ilots Iof Ifluids. I Acute Ilaryngotracheobronchitis
5. Types Iof Ianemia Ipg. I982-1102 IC. I28 Ireduction Iof Ithe Itotal Inumber Iof Ierythrocytes Iin Ithe
circulating Iblood Ior Ia Idecrease Iin Ithe Iquality Ior Iquantity Iof Ihemoglobin
a. Macrocytic-normochromic Ianemia- Ilarge Iabnormally Ishaped Ierythrocytes Ibut Inormal
Ihemoglobin Iconcentrations I(Pernicious- Ilack Iof IB12, Iabnormal IRNA Iand IDNA Isynthesis
Iand Iearly Icell Ideath, Ifolate Ideficiency- Ilack Iof Ifolate Ifor Ierythropoiesis Ipremature Icell
Ideath)
b. Microcytic-hypochromic Ianemia- ISmall Iabnormally Ishaped Ierythrocytes Iand Ireduced
hemoglobin Iconcentration I(Iron Ideficiency- Ilack Iof IFe Ifor Ihemoglobin Iproduction,
Iinsufficient Ihemo, Isideroblastic- Idysfunctional Iiron Iuptake Iby Ierythroblasts Iand Idefective
Iporphyrin Iand Iheme Isynthesis, Ithalassemia- Iimpaired Isynthesis Iof Ialpha Iand Ibeta Ichain
Iof Ihemoglobin, Iphagocytosis Iof Iabnormal Ierythroblasts Iin Ithe Imarrow)
c. Normocytic-normochromic Ianemia- Inormal Isize, Inormal Ihemo Iconcentration I(aplastic-
insufficient Ierythropoiesis, Iposthemorrhagic- Iblood Ilost, Ihemolytic- Ipremature
Idestruction Iof Imature Ierythrocytes Iin Ithe Icirculation, Isickle Icell- Iabnormal Ihemo
Isynthesis, Iabnormal Icell Ishape Iwith Idamage, Ilysis Iand Iphagocytosis, I anemia Iof Ichronic
Idisease- Iabnormal Idemand Ifor Inew Ierythrocytes I)
6. The Iinflammatory Iprocess Iupon Iinjury Ipg. I195 ICh. I7- Iblood Ivessel Idilation, Iincreased Ivascular
permeability Iand Ileakage Iof Ifluid Iout Iof Ithe Ivessel, IWBC Iadherence Ito Ithe Iinner Iwalls Iof ItheIvessel
Iand Itheir Imigration Ithrough Ivessel Iwalls Ito Ithe Isite Iof Iinjury. IFigure I7-2
7. GI Isymptoms Iresulting Iin Iheart Iburn- Ipg. I1429 ICh I41. Iacid Iregurg Ichronic Icough, Iasthma Iattacks,
and Ilaryngitis. IUpper Iabd Ipain, Iwithin I1 Ihr Iof Ieating, Iworse Ilying Idown, Ichest Ipain,
8. Pulmonary Iterminology I- Idyspnea- ISOB, IOrthopnea- Ipostural ISOB ICh I35 Ipg. I1248
9. Complications Iof Igastric Iresection Isurgery-pg I1440 Idumping Isyndrome,
, 10. Dermatology Iterminology-Ch. I46, Ipg. I1620, Imacules- Ifreckles, Iflat Imoles, Ichange Iin Icolor, Iless
Ithan1 Icm, Inevi- Imoles Ipg. I1641, Ietc-
11. Chicken Ipox- Ipg. I1660, Ich. I47. Idisease Iof Iearly Ichildhood, Ihighly Icontagious Ivirus, Ivesicles, Itrunk,
scalp, Ior Iface, Itransmission I5-6 Idays Iafter Ifirst Ivesicle, Icontagious I1 Iday Iprior Ito Irash, IcontagiousIfor
I7-10 Idays,
12. Maternal Iimmune Isystem- Ipg. I1059. IABO Iincompatibility
13. Candidiasis Iexacerbation- Ipg. I1638 Iyeast Ilike Ifungus Iin Imoist Iareas,
14. Carbuncles- Ipg. I1635 Icollection Iof Iinfected Ihair Ifollicles Ioccurring Iusually Iat Ithe Iback Iof Ithe Ineck,
Iupper Iback, Iand Ilateral Ithighs
15. Terms Isuch Ias Ihypochromic, Imacrocytic, Imicrocytic, Ietc Ipg. I983 ICh I28
a. Hypochromic- Ilower Ihemoglobin Icontent
b. Macrocytic- Ihigher Ierythrocyte Ivolume
c. Microcytic- Ilower Ierythrocyte Ivolume
d. Hyperchromic- Ihigher Ihemoglobin Iconcentration
e. Normochromic- Ihemo Iconcentration Inormal
f. Normocytic- Inormal Ierythrocyte Iconcentration
16. Antibodies Ipg. I229-230 IIgG- Imost Iabundant I80-85%, Iprotective Iactivity, IIgA- Inormal Ibody
Isecretions Ihighest Iamount Ihere, IIgM- Ilargest Ifirst Iproduced Iin Iinitial Ior Iprimary Iresponse, Iearly
Iin Ineonatal Ilife, IIgD- Ilow Iconcentrations, Ibcell Iantigen Ireceptor, IIgE Ileast Iconcentrated- Imediator
Iof Iallergic Iresponses
17. Skin Icancer- Ipg. I1641. Ibasal Icarcinoma Iand Isquamous Icell Icarcinoma Imost Icommon
18. Parts Iof Ithe Iheart Iin Iterms Iof Ifunction ICh. I31 Ipg. I1085 Ipericardium- Idouble Iwall Imembrane
Iaround Ithe Iheart, Iprevents Idisplacement Iof Ithe Iheart, Iphysical Ibarrier Iand Icontracts Ipain
Ireceptors Iand Imechanoreceptors Ithat Ielicit Ichanges Ito IBP Iand Iheart Irate
19. Congenital Iheart Idefects- Ipg. I1198 Ileading Icause Iof Ideath Iin Ithe Ifirst Iyear Iof Ilife Iminus
prematurity. IEtiology Iusually Iunknown.
20. Urinary Itract Iobstruction- Ipg. I1341 ICh I38- Iinterference Iwith Ithe Iflow Iof Iurine Iat Iany Isite Ialong
Ithe Iurinary Itract
21. GI Isymptoms Iof Iconditions ICh. I41
a. pyloric Istenosis- Ifullness, Inausea, Iepigatric Ipain Ipg. I1430
b. hiatal Ihernia- Iasymptomatic, Iassociated Iwith IGERd Isymptoms, Idysphagia, Iepigastric Ipain
Ipg I1430
c. ulcerative Icolitis- Iwatery Idiahhrea, Ibleeding Iand Icramping, Iurge Ito Ipoop, Idehydration,
weight Iloss, Ianemia, Iand Ifever Ipg. I1442
22. Skin Icancer Ilesions-pg. I1642 Isuperficial, Inodular, Isclerosis/morpheaform, Ican Ibe Ipigmented Ior
Inon Ipigmented.
23. Gastroesophageal Ireflux Idisease- Ipg, I1429 ICh I41- Ireflux Iof Iacid Iand Ipepsin Ifrom Istomach, Ito Ithe
esophagus, Irisk Ifactors Iobesity, Ihiatal Ihernia, Idrugs Ior Ichemicals
24. Hypersensitivity Ireaction- Ipg. I263
a. Type I1 IIgE Imediated- Iimmediate, Iproducts Iof Imast Icells, Imost Icommon Ifor Iallergies
b. Type I2 Itissue Ispecific- Iimmediate, Ispecific Icell Ior Itissue Ibeing Ithe Itarget Iof Ian Iimmune
Iresponse, IIgG Iand IIgM, Imacrophages Iin Itissues, Icomplement Iparticipated Ifrequently,
Iautoimmune Ithrombocytopenia Ipurpura, Igraves, Ihemolytic Ianemia
c. Type I3 Iimmune Icomplex- Iimmediate, IIgG Iand IIgM, INeutrophils, Icompletment Idoes
participate, Isystemic Ilupus
1. Types Iof Iimmunity Ich I7 I& I8
a. Innate- Inatural Iepithelial Ibarrier Iand Iinflammation Ithe Imake Iinnate Iresistance Iand
Iprotection Ipg. I191
b. Adaptive/ Iacquired- Iimmune Iresponse Ior Iimmunity, Iafter Iinnate Iand Iinflammation,
i. Active I(Acquired) I-after Inatural Iexposure Ito Ian Iantigen Ior Iafter Iimmunization Ipg.
I227
ii. Passive I(Acquired)- Ipreformed Iantibodies Ior It Ilymphocytes Iare Itransferred Irom Ia
donor Ito Ithe Irecipient, Imaternal Ito Ifetus, Ior Ibone Imarrow Itransplant Ipg. I227
2. Alveolar Iventilation/perfusion- Ipg. I1239 ICh I34
a. Ratio Ibetween Ithe Iamount Iof Iair Igetting Iinto Ithe Ialveoli Iand Ithe Iamount Iof Iblood Ibeing
Isent Ito Ithe Ilungs.
3. Dermatologic Iconditions I ch. I46 Ie.g. Ipityriasis Irosea- Ibenign Iself-limiting Iinflammatory Idisorder
that Ioccurs Iin Iyoung Iadults, Iwith Iseasonal Ipeaks Ispring Iand Ifall. IHarmful Iin Ipregnancy.
IAssociated Iwith Ia Ivirus, Istarts Iwith Ia Iherald Ipatch, Icircular. ISalmon Ipink, Iand Idemarcated, Iusually
Ion Ithe Itrunk, Iacyclovir Iand Ierythromycin, Iand Icorticosteroid Icreams Ifor Iitching. IShould Igo Iaway
Iwithin Ia Ifew Imonths.
4. Croup- Ipg. I1294-1296 IViral, Ibarking Icough, Iwinter Iand Ispring Imonths, Iusually Iaffects Ichildren I6
mo Ito I3 Iyrs, Ipeak Iat I2 Iyears Iold, Istridor, Iand Ifever, I2-5 Idays. Ihuman Iparainfluenza Iviruses I(HPIVs),
IRSV, I viruses Iare Iairborne. IRest, Ihumidity, Iand Ilots Iof Ifluids. I Acute Ilaryngotracheobronchitis
5. Types Iof Ianemia Ipg. I982-1102 IC. I28 Ireduction Iof Ithe Itotal Inumber Iof Ierythrocytes Iin Ithe
circulating Iblood Ior Ia Idecrease Iin Ithe Iquality Ior Iquantity Iof Ihemoglobin
a. Macrocytic-normochromic Ianemia- Ilarge Iabnormally Ishaped Ierythrocytes Ibut Inormal
Ihemoglobin Iconcentrations I(Pernicious- Ilack Iof IB12, Iabnormal IRNA Iand IDNA Isynthesis
Iand Iearly Icell Ideath, Ifolate Ideficiency- Ilack Iof Ifolate Ifor Ierythropoiesis Ipremature Icell
Ideath)
b. Microcytic-hypochromic Ianemia- ISmall Iabnormally Ishaped Ierythrocytes Iand Ireduced
hemoglobin Iconcentration I(Iron Ideficiency- Ilack Iof IFe Ifor Ihemoglobin Iproduction,
Iinsufficient Ihemo, Isideroblastic- Idysfunctional Iiron Iuptake Iby Ierythroblasts Iand Idefective
Iporphyrin Iand Iheme Isynthesis, Ithalassemia- Iimpaired Isynthesis Iof Ialpha Iand Ibeta Ichain
Iof Ihemoglobin, Iphagocytosis Iof Iabnormal Ierythroblasts Iin Ithe Imarrow)
c. Normocytic-normochromic Ianemia- Inormal Isize, Inormal Ihemo Iconcentration I(aplastic-
insufficient Ierythropoiesis, Iposthemorrhagic- Iblood Ilost, Ihemolytic- Ipremature
Idestruction Iof Imature Ierythrocytes Iin Ithe Icirculation, Isickle Icell- Iabnormal Ihemo
Isynthesis, Iabnormal Icell Ishape Iwith Idamage, Ilysis Iand Iphagocytosis, I anemia Iof Ichronic
Idisease- Iabnormal Idemand Ifor Inew Ierythrocytes I)
6. The Iinflammatory Iprocess Iupon Iinjury Ipg. I195 ICh. I7- Iblood Ivessel Idilation, Iincreased Ivascular
permeability Iand Ileakage Iof Ifluid Iout Iof Ithe Ivessel, IWBC Iadherence Ito Ithe Iinner Iwalls Iof ItheIvessel
Iand Itheir Imigration Ithrough Ivessel Iwalls Ito Ithe Isite Iof Iinjury. IFigure I7-2
7. GI Isymptoms Iresulting Iin Iheart Iburn- Ipg. I1429 ICh I41. Iacid Iregurg Ichronic Icough, Iasthma Iattacks,
and Ilaryngitis. IUpper Iabd Ipain, Iwithin I1 Ihr Iof Ieating, Iworse Ilying Idown, Ichest Ipain,
8. Pulmonary Iterminology I- Idyspnea- ISOB, IOrthopnea- Ipostural ISOB ICh I35 Ipg. I1248
9. Complications Iof Igastric Iresection Isurgery-pg I1440 Idumping Isyndrome,
, 10. Dermatology Iterminology-Ch. I46, Ipg. I1620, Imacules- Ifreckles, Iflat Imoles, Ichange Iin Icolor, Iless
Ithan1 Icm, Inevi- Imoles Ipg. I1641, Ietc-
11. Chicken Ipox- Ipg. I1660, Ich. I47. Idisease Iof Iearly Ichildhood, Ihighly Icontagious Ivirus, Ivesicles, Itrunk,
scalp, Ior Iface, Itransmission I5-6 Idays Iafter Ifirst Ivesicle, Icontagious I1 Iday Iprior Ito Irash, IcontagiousIfor
I7-10 Idays,
12. Maternal Iimmune Isystem- Ipg. I1059. IABO Iincompatibility
13. Candidiasis Iexacerbation- Ipg. I1638 Iyeast Ilike Ifungus Iin Imoist Iareas,
14. Carbuncles- Ipg. I1635 Icollection Iof Iinfected Ihair Ifollicles Ioccurring Iusually Iat Ithe Iback Iof Ithe Ineck,
Iupper Iback, Iand Ilateral Ithighs
15. Terms Isuch Ias Ihypochromic, Imacrocytic, Imicrocytic, Ietc Ipg. I983 ICh I28
a. Hypochromic- Ilower Ihemoglobin Icontent
b. Macrocytic- Ihigher Ierythrocyte Ivolume
c. Microcytic- Ilower Ierythrocyte Ivolume
d. Hyperchromic- Ihigher Ihemoglobin Iconcentration
e. Normochromic- Ihemo Iconcentration Inormal
f. Normocytic- Inormal Ierythrocyte Iconcentration
16. Antibodies Ipg. I229-230 IIgG- Imost Iabundant I80-85%, Iprotective Iactivity, IIgA- Inormal Ibody
Isecretions Ihighest Iamount Ihere, IIgM- Ilargest Ifirst Iproduced Iin Iinitial Ior Iprimary Iresponse, Iearly
Iin Ineonatal Ilife, IIgD- Ilow Iconcentrations, Ibcell Iantigen Ireceptor, IIgE Ileast Iconcentrated- Imediator
Iof Iallergic Iresponses
17. Skin Icancer- Ipg. I1641. Ibasal Icarcinoma Iand Isquamous Icell Icarcinoma Imost Icommon
18. Parts Iof Ithe Iheart Iin Iterms Iof Ifunction ICh. I31 Ipg. I1085 Ipericardium- Idouble Iwall Imembrane
Iaround Ithe Iheart, Iprevents Idisplacement Iof Ithe Iheart, Iphysical Ibarrier Iand Icontracts Ipain
Ireceptors Iand Imechanoreceptors Ithat Ielicit Ichanges Ito IBP Iand Iheart Irate
19. Congenital Iheart Idefects- Ipg. I1198 Ileading Icause Iof Ideath Iin Ithe Ifirst Iyear Iof Ilife Iminus
prematurity. IEtiology Iusually Iunknown.
20. Urinary Itract Iobstruction- Ipg. I1341 ICh I38- Iinterference Iwith Ithe Iflow Iof Iurine Iat Iany Isite Ialong
Ithe Iurinary Itract
21. GI Isymptoms Iof Iconditions ICh. I41
a. pyloric Istenosis- Ifullness, Inausea, Iepigatric Ipain Ipg. I1430
b. hiatal Ihernia- Iasymptomatic, Iassociated Iwith IGERd Isymptoms, Idysphagia, Iepigastric Ipain
Ipg I1430
c. ulcerative Icolitis- Iwatery Idiahhrea, Ibleeding Iand Icramping, Iurge Ito Ipoop, Idehydration,
weight Iloss, Ianemia, Iand Ifever Ipg. I1442
22. Skin Icancer Ilesions-pg. I1642 Isuperficial, Inodular, Isclerosis/morpheaform, Ican Ibe Ipigmented Ior
Inon Ipigmented.
23. Gastroesophageal Ireflux Idisease- Ipg, I1429 ICh I41- Ireflux Iof Iacid Iand Ipepsin Ifrom Istomach, Ito Ithe
esophagus, Irisk Ifactors Iobesity, Ihiatal Ihernia, Idrugs Ior Ichemicals
24. Hypersensitivity Ireaction- Ipg. I263
a. Type I1 IIgE Imediated- Iimmediate, Iproducts Iof Imast Icells, Imost Icommon Ifor Iallergies
b. Type I2 Itissue Ispecific- Iimmediate, Ispecific Icell Ior Itissue Ibeing Ithe Itarget Iof Ian Iimmune
Iresponse, IIgG Iand IIgM, Imacrophages Iin Itissues, Icomplement Iparticipated Ifrequently,
Iautoimmune Ithrombocytopenia Ipurpura, Igraves, Ihemolytic Ianemia
c. Type I3 Iimmune Icomplex- Iimmediate, IIgG Iand IIgM, INeutrophils, Icompletment Idoes
participate, Isystemic Ilupus
