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Class notes PHARMACOLOGY Essentials of Medical Pharmacology, ISBN: 9789352704996

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This documents covers pharmacological actions of alcohol, acute effects of alcohol consumption, pharmacokinetics and excretion of the alcohol. Refer it and review.

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September 23, 2021
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Written in
2020/2021
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Dr. sameer sawant
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ALIPHATIC ALCOHOLS

,Ethyl Alcohol Methyl Alcohol




(Ethanol) (Methanol)

, Manufacturing
• Fermentation – Sugar to Alcohol and Carbon


dioxide
– C6H12O6→ 2(CH3-CH2-OH) + 2CO2
– (Yeasts +sugar + water = CO2 + ethanol)

– Yeasts are living micro-organisms which die in
concentrations of alcohol greater than 10 to 15%
– Starch –Convertase Maltose
• Commercially - obtained from Mollases

, Alcoholic Beverages
 Malted Liquors: Fermentation of germinating cereals (malts) –
Beers (3-6%)
 Wines: fermentation of Natural Sugars – grapes, apples and
other fruits
 No distillation, <15%
 Fortified (port) – up to 22%
 Champagne – 12-16% (effervescent wine)
 Spirits – Rum, Whisky, Brandy and Gin
 40 - 55% v/v
 Standard 42.8% v/v or 37% w/w
 Sources:
 Whiskey - distilled grain
 Rum - distilled molasses
 Gin – any sugar source
 Brandy – Distilled wine (Grapes)
 Vodka – fermentation of any of grain, rye, wheat,
potatoes, grapes, sugar beet or mollases
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