NSG 318 STUDY GUIDE 2026/2027 QUESTIONS AND
ANSWERS RATED A+
✔✔Nursing Considerations for Ivermectin - ✔✔Monitor for GI side effects, neurological
symptoms, and educate patients on avoiding alcohol use. Monitor liver and renal
function.
✔✔CLASS: Antibacterial: Peptide, Amebicide - ✔✔Prototype: metronidazole
✔✔MOA of Metronidazole - ✔✔Diffuses into organism, interacting with DNA and
causing a loss of helical DNA structure and strand breakage, inhibiting protein
synthesis.
✔✔Indications for Metronidazole - ✔✔Anaerobic infections
✔✔Side Effects of Metronidazole - ✔✔Nausea, vomiting, diarrhea, metallic taste
✔✔Adverse Reactions of Metronidazole - ✔✔Neuropathy, eye damage
✔✔Contraindications for Metronidazole - ✔✔Caution with liver dysfunction, pregnancy.
Disulfiram-like reaction: Can cause nausea, vomiting, flushing, headache, and
abdominal cramps when alcohol is consumed during treatment.
✔✔CAMS for Metronidazole - ✔✔Garlic, Echinacea - Reduced effectiveness, immune
system modulation
✔✔Nursing Considerations for Metronidazole - ✔✔Monitor for neurological side effects
(headache, dizziness), assess liver function, and educate patients to avoid alcohol due
to the risk of a disulfiram-like reaction.
✔✔Non-steroidal Anti-inflammatory Drugs - ✔✔Medications that provide relief from pain
and inflammation without the use of steroids.
✔✔Salicylate - ✔✔A class of drugs that includes aspirin, which inhibits prostaglandin
synthesis.
✔✔Aspirin - ✔✔The prototype drug of the salicylate class, used for relief of moderate to
severe pain.
✔✔MOA (Mechanism of Action) - ✔✔Inhibits prostaglandin synthesis, hypothalamic
heat regulator center, and platelet aggregation.
✔✔Indications for Aspirin - ✔✔Relief of moderate to severe pain, often used when non-
opioid analgesics are ineffective.
,✔✔Side Effects of Aspirin - ✔✔Dizziness, drowsiness, headache, nausea, vomiting,
constipation, sweating, and respiratory depression.
✔✔Adverse Reactions of Aspirin - ✔✔Tinnitus, hearing loss, hypokalemia,
hypernatremia, elevated hepatic enzymes, and GI bleeding.
✔✔Contraindications for Aspirin - ✔✔Hypersensitivity to salicylates or NSAIDs,
renal/hepatic dysfunction, and severe renal disease.
✔✔CAMS (Complementary and Alternative Medicine) - ✔✔Herbs such as ginger, garlic,
ginkgo, ginseng, fish oil, and feverfew that may interact with NSAIDs.
✔✔Nursing Considerations for Aspirin - ✔✔Assess for bleeding, educate patients to
take with food, and monitor for signs of salicylate toxicity.
✔✔Propionic Acid Derivative - ✔✔A class of NSAIDs that includes ibuprofen.
✔✔Ibuprofen - ✔✔The prototype drug of the propionic acid derivative class, used for
pain and arthritis.
✔✔MOA of Ibuprofen - ✔✔Inhibits prostaglandin synthesis.
✔✔Indications for Ibuprofen - ✔✔Pain, osteoarthritis, and rheumatoid arthritis.
✔✔Side Effects of Ibuprofen - ✔✔CNS effects, gastric distress, bleeding, and
nephrotoxicity.
✔✔Adverse Reactions of Ibuprofen - ✔✔Hearing loss, GI bleeding, tinnitus, and
anaphylaxis.
✔✔Contraindications for Ibuprofen - ✔✔Hypersensitivity, bleeding disorders, pregnancy,
and renal or hepatic disease.
✔✔Nursing Considerations for Ibuprofen - ✔✔Assess for GI distress, monitor renal
function, and educate patients on bleeding signs.
✔✔Drug Interactions with Ibuprofen - ✔✔Increased bleeding with warfarin and
decreased effect with aspirin.
✔✔Selective Cox-2 Inhibitor - ✔✔A class of drugs that selectively inhibits COX-2
enzymes, reducing inflammation with less GI risk.
, ✔✔Celecoxib (Celebrex) - ✔✔The prototype drug of the selective Cox-2 inhibitor class,
used for arthritis and pain.
✔✔MOA of Celecoxib - ✔✔Selectively inhibits COX-2 enzymes without inhibition of
COX-1.
✔✔Uses of Celecoxib - ✔✔For arthritis, lower bleeding risk, ankylosing spondylitis, pain,
and dysmenorrhea.
✔✔Side Effects of Celecoxib - ✔✔Sinusitis, CNS effects, GI distress, ulceration,
hypertension, and renal dysfunction.
✔✔Nursing Considerations for Celecoxib - ✔✔No alcohol or other NSAIDs, monitor for
drug interactions, and ensure adequate hydration.
✔✔Immunomodulator - ✔✔A class of drugs that help calm the immune system and
relieve joints, with infliximab (Remicade) as the prototype.
✔✔Infliximab (Remicade) - ✔✔Prototype of immunomodulators that binds to TNF and
blocks it from attaching to TNF receptors.
✔✔MOA of Immunomodulators - ✔✔Helps calm the immune system and relieve joints
by binding to TNF.
✔✔Uses of Immunomodulators - ✔✔Used for Lupus, Crohn's disease, arthritis, and
colitis.
✔✔Admin of Immunomodulators - ✔✔Administered via IV infusion over at least 2 hours.
✔✔Contraindications of Immunomodulators - ✔✔Hypersensitivity and heart failure.
✔✔CAMS for Immunomodulators - ✔✔Echinacea.
✔✔DD Interactions of Immunomodulators - ✔✔Live vaccines.
✔✔Nursing Considerations for Immunomodulators - ✔✔Need a CBC to take the drug;
come in consistently for CBCs and liver tests.
✔✔Raw or Undercooked Foods - ✔✔Should be avoided when taking
immunomodulators to reduce the risk of foodborne infections.
✔✔Anti-Gout - ✔✔A class of drugs with allopurinol as the prototype, used to lower uric
acid levels.
ANSWERS RATED A+
✔✔Nursing Considerations for Ivermectin - ✔✔Monitor for GI side effects, neurological
symptoms, and educate patients on avoiding alcohol use. Monitor liver and renal
function.
✔✔CLASS: Antibacterial: Peptide, Amebicide - ✔✔Prototype: metronidazole
✔✔MOA of Metronidazole - ✔✔Diffuses into organism, interacting with DNA and
causing a loss of helical DNA structure and strand breakage, inhibiting protein
synthesis.
✔✔Indications for Metronidazole - ✔✔Anaerobic infections
✔✔Side Effects of Metronidazole - ✔✔Nausea, vomiting, diarrhea, metallic taste
✔✔Adverse Reactions of Metronidazole - ✔✔Neuropathy, eye damage
✔✔Contraindications for Metronidazole - ✔✔Caution with liver dysfunction, pregnancy.
Disulfiram-like reaction: Can cause nausea, vomiting, flushing, headache, and
abdominal cramps when alcohol is consumed during treatment.
✔✔CAMS for Metronidazole - ✔✔Garlic, Echinacea - Reduced effectiveness, immune
system modulation
✔✔Nursing Considerations for Metronidazole - ✔✔Monitor for neurological side effects
(headache, dizziness), assess liver function, and educate patients to avoid alcohol due
to the risk of a disulfiram-like reaction.
✔✔Non-steroidal Anti-inflammatory Drugs - ✔✔Medications that provide relief from pain
and inflammation without the use of steroids.
✔✔Salicylate - ✔✔A class of drugs that includes aspirin, which inhibits prostaglandin
synthesis.
✔✔Aspirin - ✔✔The prototype drug of the salicylate class, used for relief of moderate to
severe pain.
✔✔MOA (Mechanism of Action) - ✔✔Inhibits prostaglandin synthesis, hypothalamic
heat regulator center, and platelet aggregation.
✔✔Indications for Aspirin - ✔✔Relief of moderate to severe pain, often used when non-
opioid analgesics are ineffective.
,✔✔Side Effects of Aspirin - ✔✔Dizziness, drowsiness, headache, nausea, vomiting,
constipation, sweating, and respiratory depression.
✔✔Adverse Reactions of Aspirin - ✔✔Tinnitus, hearing loss, hypokalemia,
hypernatremia, elevated hepatic enzymes, and GI bleeding.
✔✔Contraindications for Aspirin - ✔✔Hypersensitivity to salicylates or NSAIDs,
renal/hepatic dysfunction, and severe renal disease.
✔✔CAMS (Complementary and Alternative Medicine) - ✔✔Herbs such as ginger, garlic,
ginkgo, ginseng, fish oil, and feverfew that may interact with NSAIDs.
✔✔Nursing Considerations for Aspirin - ✔✔Assess for bleeding, educate patients to
take with food, and monitor for signs of salicylate toxicity.
✔✔Propionic Acid Derivative - ✔✔A class of NSAIDs that includes ibuprofen.
✔✔Ibuprofen - ✔✔The prototype drug of the propionic acid derivative class, used for
pain and arthritis.
✔✔MOA of Ibuprofen - ✔✔Inhibits prostaglandin synthesis.
✔✔Indications for Ibuprofen - ✔✔Pain, osteoarthritis, and rheumatoid arthritis.
✔✔Side Effects of Ibuprofen - ✔✔CNS effects, gastric distress, bleeding, and
nephrotoxicity.
✔✔Adverse Reactions of Ibuprofen - ✔✔Hearing loss, GI bleeding, tinnitus, and
anaphylaxis.
✔✔Contraindications for Ibuprofen - ✔✔Hypersensitivity, bleeding disorders, pregnancy,
and renal or hepatic disease.
✔✔Nursing Considerations for Ibuprofen - ✔✔Assess for GI distress, monitor renal
function, and educate patients on bleeding signs.
✔✔Drug Interactions with Ibuprofen - ✔✔Increased bleeding with warfarin and
decreased effect with aspirin.
✔✔Selective Cox-2 Inhibitor - ✔✔A class of drugs that selectively inhibits COX-2
enzymes, reducing inflammation with less GI risk.
, ✔✔Celecoxib (Celebrex) - ✔✔The prototype drug of the selective Cox-2 inhibitor class,
used for arthritis and pain.
✔✔MOA of Celecoxib - ✔✔Selectively inhibits COX-2 enzymes without inhibition of
COX-1.
✔✔Uses of Celecoxib - ✔✔For arthritis, lower bleeding risk, ankylosing spondylitis, pain,
and dysmenorrhea.
✔✔Side Effects of Celecoxib - ✔✔Sinusitis, CNS effects, GI distress, ulceration,
hypertension, and renal dysfunction.
✔✔Nursing Considerations for Celecoxib - ✔✔No alcohol or other NSAIDs, monitor for
drug interactions, and ensure adequate hydration.
✔✔Immunomodulator - ✔✔A class of drugs that help calm the immune system and
relieve joints, with infliximab (Remicade) as the prototype.
✔✔Infliximab (Remicade) - ✔✔Prototype of immunomodulators that binds to TNF and
blocks it from attaching to TNF receptors.
✔✔MOA of Immunomodulators - ✔✔Helps calm the immune system and relieve joints
by binding to TNF.
✔✔Uses of Immunomodulators - ✔✔Used for Lupus, Crohn's disease, arthritis, and
colitis.
✔✔Admin of Immunomodulators - ✔✔Administered via IV infusion over at least 2 hours.
✔✔Contraindications of Immunomodulators - ✔✔Hypersensitivity and heart failure.
✔✔CAMS for Immunomodulators - ✔✔Echinacea.
✔✔DD Interactions of Immunomodulators - ✔✔Live vaccines.
✔✔Nursing Considerations for Immunomodulators - ✔✔Need a CBC to take the drug;
come in consistently for CBCs and liver tests.
✔✔Raw or Undercooked Foods - ✔✔Should be avoided when taking
immunomodulators to reduce the risk of foodborne infections.
✔✔Anti-Gout - ✔✔A class of drugs with allopurinol as the prototype, used to lower uric
acid levels.
