1|Page
NCLEX ENDOCRINE
COMPREHENSIVE PRACTICE EXAM
TEST BANK QUESTIONS AND
CORRECT DETAILED ANSWERS
|LATEST 2026-2027 VERSION |RATED A
+
Early this morning, a female client had a subtotal thyroidectomy. During
evening rounds, nurse Tina assesses the client, who now has nausea, a
temperature of 105° F (40.5° C), tachycardia, and extreme restlessness.
What is the most likely cause of these signs?
a. Diabetic ketoacidosis
b. Thyroid crisis
c. Hypoglycemia
d. Tetany - ANSWER- b. Thyroid crisis
Thyroid crisis usually occurs in the first 12 hours after
thyroidectomy and causes exaggerated signs of hyperthyroidism,
such as high fever, tachycardia, and extreme restlessness. Diabetic
ketoacidosis is more likely to produce polyuria, polydipsia, and
polyphagia; hypoglycemia, to produce weakness, tremors, profuse
perspiration, and hunger. Tetany typically causes uncontrollable
muscle spasms, stridor, cyanosis, and possibly asphyxia.
,2|Page
Nurse Louie is developing a teaching plan for a male client diagnosed
with diabetes insipidus. The nurse should include information about
which hormone lacking in clients with diabetes insipidus?
a. antidiuretic hormone (ADH).
b. thyroid-stimulating hormone (TSH).
c. follicle-stimulating hormone (FSH).
d. luteinizing hormone (LH). - ANSWER- a. antidiuretic hormone
(ADH).
ADH is the hormone clients with diabetes insipidus lack. The client's
TSH, FSH, and LH levels won't be affected.
A male client is admitted for treatment of the syndrome of inappropriate
antidiuretic hormone (SIADH). Which nursing intervention is
appropriate?
a. Infusing I.V. fluids rapidly as ordered
b. Encouraging increased oral intake
c. Restricting fluids
d. Administering glucose-containing I.V. fluids as ordered - ANSWER-
c. Restricting fluids
,3|Page
To reduce water retention in a client with the SIADH, the nurse
should restrict fluids. Administering fluids by any route would
further increase the client's already heightened fluid load.
Nurse Troy is aware that the most appropriate for a client with Addison's
disease?
a. Risk for infection
b. Excessive fluid volume
c. Urinary retention
d. Hypothermia - ANSWER- a. Risk for infection
Addison's disease decreases the production of all adrenal hormones,
compromising the body's normal stress response and increasing the
risk of infection. Other appropriate nursing diagnoses for a client
with Addison's disease include Deficient fluid volume and
Hyperthermia. Urinary retention isn't appropriate because
Addison's disease causes polyuria.
A female client with hypothyroidism (myxedema) is receiving
levothyroxine (Synthroid), 25 mcg P.O. daily. Which finding should
nurse Hans recognize as an adverse drug effect?
a. Dysuria
b. Leg cramps
c. Tachycardia
, 4|Page
d. Blurred vision - ANSWER- c. Tachycardia
Levothyroxine, a synthetic thyroid hormone, is given to a client with
hypothyroidism to simulate the effects of thyroxine. Adverse effects
of this agent include tachycardia. The other options aren't
associated with levothyroxine.
Which of these signs suggests that a male client with the syndrome of
inappropriate antidiuretic hormone (SIADH) secretion is experiencing
complications?
a. Tetanic contractions
b. Neck vein distention
c. Weight loss
d. Polyuria - ANSWER- b. Neck vein distention
SIADH secretion causes antidiuretic hormone overproduction,
which leads to fluid retention. Severe SIADH can cause such
complications as vascular fluid overload, signaled by neck vein
distention. This syndrome isn't associated with tetanic contractions.
It may cause weight gain and fluid retention (secondary to oliguria).
Which outcome indicates that treatment of a male client with diabetes
insipidus has been effective?
a. Fluid intake is less than 2,500 ml/day.
NCLEX ENDOCRINE
COMPREHENSIVE PRACTICE EXAM
TEST BANK QUESTIONS AND
CORRECT DETAILED ANSWERS
|LATEST 2026-2027 VERSION |RATED A
+
Early this morning, a female client had a subtotal thyroidectomy. During
evening rounds, nurse Tina assesses the client, who now has nausea, a
temperature of 105° F (40.5° C), tachycardia, and extreme restlessness.
What is the most likely cause of these signs?
a. Diabetic ketoacidosis
b. Thyroid crisis
c. Hypoglycemia
d. Tetany - ANSWER- b. Thyroid crisis
Thyroid crisis usually occurs in the first 12 hours after
thyroidectomy and causes exaggerated signs of hyperthyroidism,
such as high fever, tachycardia, and extreme restlessness. Diabetic
ketoacidosis is more likely to produce polyuria, polydipsia, and
polyphagia; hypoglycemia, to produce weakness, tremors, profuse
perspiration, and hunger. Tetany typically causes uncontrollable
muscle spasms, stridor, cyanosis, and possibly asphyxia.
,2|Page
Nurse Louie is developing a teaching plan for a male client diagnosed
with diabetes insipidus. The nurse should include information about
which hormone lacking in clients with diabetes insipidus?
a. antidiuretic hormone (ADH).
b. thyroid-stimulating hormone (TSH).
c. follicle-stimulating hormone (FSH).
d. luteinizing hormone (LH). - ANSWER- a. antidiuretic hormone
(ADH).
ADH is the hormone clients with diabetes insipidus lack. The client's
TSH, FSH, and LH levels won't be affected.
A male client is admitted for treatment of the syndrome of inappropriate
antidiuretic hormone (SIADH). Which nursing intervention is
appropriate?
a. Infusing I.V. fluids rapidly as ordered
b. Encouraging increased oral intake
c. Restricting fluids
d. Administering glucose-containing I.V. fluids as ordered - ANSWER-
c. Restricting fluids
,3|Page
To reduce water retention in a client with the SIADH, the nurse
should restrict fluids. Administering fluids by any route would
further increase the client's already heightened fluid load.
Nurse Troy is aware that the most appropriate for a client with Addison's
disease?
a. Risk for infection
b. Excessive fluid volume
c. Urinary retention
d. Hypothermia - ANSWER- a. Risk for infection
Addison's disease decreases the production of all adrenal hormones,
compromising the body's normal stress response and increasing the
risk of infection. Other appropriate nursing diagnoses for a client
with Addison's disease include Deficient fluid volume and
Hyperthermia. Urinary retention isn't appropriate because
Addison's disease causes polyuria.
A female client with hypothyroidism (myxedema) is receiving
levothyroxine (Synthroid), 25 mcg P.O. daily. Which finding should
nurse Hans recognize as an adverse drug effect?
a. Dysuria
b. Leg cramps
c. Tachycardia
, 4|Page
d. Blurred vision - ANSWER- c. Tachycardia
Levothyroxine, a synthetic thyroid hormone, is given to a client with
hypothyroidism to simulate the effects of thyroxine. Adverse effects
of this agent include tachycardia. The other options aren't
associated with levothyroxine.
Which of these signs suggests that a male client with the syndrome of
inappropriate antidiuretic hormone (SIADH) secretion is experiencing
complications?
a. Tetanic contractions
b. Neck vein distention
c. Weight loss
d. Polyuria - ANSWER- b. Neck vein distention
SIADH secretion causes antidiuretic hormone overproduction,
which leads to fluid retention. Severe SIADH can cause such
complications as vascular fluid overload, signaled by neck vein
distention. This syndrome isn't associated with tetanic contractions.
It may cause weight gain and fluid retention (secondary to oliguria).
Which outcome indicates that treatment of a male client with diabetes
insipidus has been effective?
a. Fluid intake is less than 2,500 ml/day.
