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Exam (elaborations)

GMS 6474 Cardiovascular and Muscle Physiology Final Exam QUESTIONS WITH ANSWERS

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GMS 6474 Cardiovascular and Muscle Physiology Final Exam QUESTIONS WITH ANSWERS

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January 23, 2026
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Written in
2025/2026
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GMS 6474: Cardiovascular and Muscle|\ |\ |\ |\ |\




Physiology Final Exam QUESTIONS |\ |\ |\ |\




WITH ANSWERS |\




The tendon is responsible for... - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\



✔✔Keeping the skeletal muscle attached to the bone |\ |\ |\ |\ |\ |\ |\




The tendon is made up of connective tissue at what three
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\



layers? From smallest to largest groupings. - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\



ANSWERS ✔✔(1) Endomysium |\ |\




(2) Perimysium
|\




(3) Epimysium
|\




What regulates protein synthesis throughout the muscle
|\ |\ |\ |\ |\ |\ |\



cell? - CORRECT ANSWERS ✔✔Myonuclei
|\ |\ |\ |\




What type of cells assists in repairing muscle damage? -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\



CORRECT ANSWERS ✔✔Satellite Cells |\ |\ |\




The Isotropic Band (I Band) of the sarcomere is composed
|\ |\ |\ |\ |\ |\ |\ |\ |\



of... - CORRECT ANSWERS ✔✔Thin Filaments
|\ |\ |\ |\ |\ |\




Titin
Z disk
|\

,The A Band of the sarcomere is composed of... - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\



ANSWERS ✔✔Thin Filaments
|\ |\ |\




Thick Filaments |\




The H Zone of the sarcomere is composed of... - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\



ANSWERS ✔✔Only the thick filament without the myosin
|\ |\ |\ |\ |\ |\ |\ |\ |\



heads


During contraction of the sarcomere, what change occurs
|\ |\ |\ |\ |\ |\ |\ |\



in the thin and thick filaments? - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\ |\



✔✔The amount of overlap between the two
|\ |\ |\ |\ |\ |\




The SR is responsible for... - CORRECT ANSWERS ✔✔The
|\ |\ |\ |\ |\ |\ |\ |\ |\



storage and release of Ca++ |\ |\ |\ |\




How does each myofibril have access to the extracellular
|\ |\ |\ |\ |\ |\ |\ |\ |\



fluid? - CORRECT ANSWERS ✔✔Via the T tubules
|\ |\ |\ |\ |\ |\ |\




Dihydropyridine Receptors (DHPR) are found in the |\ |\ |\ |\ |\ |\ |\



__________ and they are ________ receptors - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\



ANSWERS ✔✔T tubule ; Voltage |\ |\ |\ |\

,Ryanodine Receptors (RyR) are found in the _______ and |\ |\ |\ |\ |\ |\ |\ |\ |\



they are _______________ channels. - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\



✔✔SR ; Calcium Release Channels|\ |\ |\ |\




The thick filament's molecular structure is composed of
|\ |\ |\ |\ |\ |\ |\ |\



what 2 things? - CORRECT ANSWERS ✔✔(1) Myosin
|\ |\ |\ |\ |\ |\ |\




(2) Titin |\




F-actin in the thin filament is... - CORRECT ANSWERS ✔✔A
|\ |\ |\ |\ |\ |\ |\ |\ |\



helix of globular G actin that exposes an active site in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\



which the myosin head can bind to
|\ |\ |\ |\ |\ |\




Tropomyosin is a single strand protein that... - CORRECT |\ |\ |\ |\ |\ |\ |\ |\ |\



ANSWERS ✔✔Covers the active site fount on F-actin |\ |\ |\ |\ |\ |\ |\




The troponin complex in the presence of Ca++ can... -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\



CORRECT ANSWERS ✔✔Move tropomyosin to expose the |\ |\ |\ |\ |\ |\ |\



active site of F-actin |\ |\ |\




CapZ anchors _______ to the ___________ of the sarcomere
|\ |\ |\ |\ |\ |\ |\ |\



- CORRECT ANSWERS ✔✔Actin ; Z-disk
|\ |\ |\ |\ |\ |\




Dystrophin connects the sarcomere to the _______ & |\ |\ |\ |\ |\ |\ |\ |\



__________. Without it there would be significant cell |\ |\ |\ |\ |\ |\ |\ |\

, damage during contraction - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\



✔✔Extracellular fluid; Sarcolemma |\ |\




The presynaptic membrane contains what two things? -
|\ |\ |\ |\ |\ |\ |\ |\



CORRECT ANSWERS ✔✔(1) Mitochondria |\ |\ |\




(2) Acetylcholine Vesicles
|\ |\




What happens during the activation of the presynaptic
|\ |\ |\ |\ |\ |\ |\ |\



membrane? - CORRECT ANSWERS ✔✔Acetylcholine |\ |\ |\ |\ |\



vesicles fuse and release their contents into the synaptic
|\ |\ |\ |\ |\ |\ |\ |\ |\



cleft


As acetylcholine diffuses across the synaptic cleft, it binds
|\ |\ |\ |\ |\ |\ |\ |\



to ___________. What does this binding lead to an
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\



activation of? - CORRECT ANSWERS ✔✔Nicotinic |\ |\ |\ |\ |\ |\



Receptors ; Increased Na+/K+ permeability |\ |\ |\ |\




Standard activation of nicotinic receptors causes? -
|\ |\ |\ |\ |\ |\ |\



CORRECT ANSWERS ✔✔A shift in membrane potential (-
|\ |\ |\ |\ |\ |\ |\



80mV ——> -15mV) |\ |\




What are the 3 phases of excitation-contraction coupling?
|\ |\ |\ |\ |\ |\ |\



- CORRECT ANSWERS ✔✔(1) Action Potential Propagation
|\ |\ |\ |\ |\ |\ |\




(2) Ca++ Release
|\ |\




(3) Exposure of Actin Active Sites
|\ |\ |\ |\ |\

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