b6
ationales for Nursing Practice 13th Edition (Vers
ion 2024/2025) Geralyn Frandsen
, GRADESBOOST.COM
Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–
compulsive4ndisorder4nhas4nbeen4nprescribed4noral4nparoxetine4nhydrochloride.4nWha
t4nis4nthe4nexpected4neffect4nfor4nthis4nprescription?
A. Curative4neffect4n on4 n symptoms
B. Systemic4n effect4n on4n symptoms
C. Local4n effect4non4 n symptoms
D. Parenteral4neffect4non4n symptoms
ANS:4 n 4 n B
Rationale:4nDrugs4nthat4nproduce4nsystemic4neffects4nare4ntaken4ninto4nthe4nbody,4ncirculated4nthr
ough4 n the4nbloodstream4nto4ntheir4nsites4nof4naction4nin4nvarious4nbody4ntissues,4nand4neventually
4neliminated4 n from4 n the4 n body.4 n Curative4 n agents4 n are4 n given4 n to4 n cure4 n a4 n disease4 n proces
s.4 n In4 n this4 n case,4 n paroxeti4nne4nhydrochloride4nwill4ncontrol4nthe4nsymptoms4nbut4nnot4ncure4nt
he4ndisorder.4nDrugs4nwith4nlocal4neff4nects,4nsuch4nas4nsunscreen4nand4nlocal4nanesthetics,4nact4n
mainly4nat4nthe4nsite4nof4napplication.4nParoxet4 n ine4nhydrochloride4nis4nnot4nadministered4npar
enterally.4nParenteral4nagents4nare4nadministered4nsub4ncutaneously,4nintramuscularly,4nor4nintra
venously.
PTS: 1 REF: p.4 n 3,4 n Introduction OBJ: 1
GRADESBOOST.COM
NAT:4 n Client4nNeeds:4nPhysiological4nIntegrity:4nPharmacological4nand4nParenteral4nT
herapi4nes4nTOP:
Chapter:4n1:4nThe4nFoundation4nof4nPharmacology:4 n Quality4nand4 n Safety
4 n KEY:4 n Integrated4nProcess:4nNursing4nProcess
BLM:4 n 4 n Cognitive4n Level:4 n Understand NOT:4 n 4 n Multiple4 n Choice
2. A4nclient4nhas4nbeen4nprescribed4nan4nantibiotic.4nThis4nmedication4nis4na4nnaturally4nocc
urring4nsubstance4nthat4nhas4nbeen4ncheG
mR icAalDlyEm
SoBdOifOieSd.TW
.hCaOt Mi4ns4 n another4nname4nf
b6
or4nthis4ntype4no
f4 n medication?
A. Synthetic4ndrug
B. Semisynthetic4ndrug
C. Biotechnology4ndrug
D. Prototype4ndrug
ANS:4 n 4 n B
Rationale:4nSemisynthetic4ndrugs4n(e.g.,4nmany4nantibiotics)4nare4nnaturally4noccurring4nsubsta
nces4nthat4nhave4nbeen4nchemically4nmodified.4nSynthetic4ndrugs4nare4nmore4nstandardized4nin4nt
heir4nchemic4nal4ncharacteristics,4nmore4nconsistent4nin4ntheir4neffects,4nand4nless4nlikely4nto4npro
duce4nallergic4nreact4nions.4nBiotechnology4ndrugs4ninvolve4nmanipulating4nDNA4nand4nRNA4n
and4nrecombining4ngenes4ni4nnto4nhybrid4nmolecules4nthat4ncan4nbe4ninserted4ninto4nliving4norgan
isms.4nPrototype4ndrugs4nare4nthe4nf4nirst4ndrug4nof4na4nparticular4ngroup4nto4nbe4ndeveloped.
PTS: 1 REF: p.4 n 3,4 n Drug4 n Sources OBJ: 1
NAT:4 n Client4nNeeds:4nPhysiological4nIntegrity:4nPharmacological4nand4nParenteral4nT
herapi4nes4nTOP:
Chapter:4n1:4nThe4nFoundation4nof4nPharmacology:4 n Quality4nand4 n Safety
4 n KEY:4 n Integrated4nProcess:4nNursing4nProcess
BLM:4 n 4 n Cognitive4n Level:4 n Understand NOT:4 n 4 n Multiple4 n Choice
3. Which4nclassification4napplies4n to4 n morphine?
A. Central4nnervous4nsystem4n depressant
B. Central4nnervous4nsystem4nstimulant
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GRADESBOOST.COM4n#14nTEST4nBANKS4nWEBSITE
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C. Anti-inflammatory
D. Antihypertensive
ANS:4 n 4 n A
Rationale:4nDrugs4nare4nclassified4naccording4nto4ntheir4neffects4non4nparticular4nbody4nsystems,4
ntheir4ntherapeutic4nuses,4nand4ntheir4nchemical4ncharacteristics.4nMorphine4nis4nclassified4nas4na4
ncentral4nne4nrvous4nsystem4ndepressant4 n and4nwill4nproduce4nthis4neffect4nin4nthe4nclient.4nA4ncen
tral4nnervous4nsyste4 n m4nstimulant4nincreases4nattention4nand4nraises4nmood.4nAn4nanti-
inflammatory4nagent4ndecreases4ninflammation4nat4nthe4nsite4nof4ntissue4nor4njoint4ninflammatio
n.4nAn4nantihypertensive4nagent4nreduces4nblood4npressure.
PTS: 1 REF:
p.4n3,4nDrug4nClassifications4nand4nPrototypes4 n OBJ: 1
NAT:4 n Client4nNeeds:4nPhysiological4nIntegrity:4nPharmacological4nand4nParenteral4nT
herapi4nes4nTOP:
Chapter:4n1:4nThe4nFoundation4nof4nPharmacology:4 n Quality4nand4 n Safety
4 n KEY:4 n Integrated4nProcess:4nNursing4nProcess
BLM:4 n 4 n Cognitive4n Level:4 n Remember NOT:4 n 4 n Multiple4 n Choice
4. A4nclient4nis4nadministered4namoxicillin.4nThe4ngeneric4nname4nof4nthis4nmedication4nbelongs4n
to4nwhi4nch4ndrug4ngroup?
A. Selective4nserotonin4nreuptake4ninhibitors
B. Diuretics
C. Penicillins
D. ACE4 n inhibitors
ANS:4 n 4 n C
G4nR4nA4nD4nE4nS4nB4nO4nO4nS4nT4n.4nC4nO4nM
Rationale:4nThe4ngeneric4nnamGeRoAfD
b6 teE n SinBdO
b6 icO
atS
esTt.hC
b6 eO
b6 drug4 n group4n(e.g.,4ndrugs4nwith4ngeneric4n
nam4nes4n ending4n in4n ―cillin‖4n are4 n penicillins).4nSelective4n serotonin4 nreuptake4 ninhibitors4 n a
re4nmedicatio
ns4nthat4nhave4nantidepressant4neffects;4nSSRI4nis4na4nbroad4nclassification,4nnot4na4ngeneric4nnam
e.4nDiur4netics4nare4nmedications4nthat4nincrease4nurine4noutput;4ndiuretic4nis4na4nbroad4nclassifica
tion,4nnot4na4nge4nneric4nname.4nACE4ninhibitor4nis4nthe4nbroad4nclassification4nfor4nthe4nangioten
sin4nreceptor4nblockers,4nnot4nthe4ngeneric4nname.
PTS: 1 REF: p.4 n 3,4 n Drug4 n Names OBJ: 2
NAT:4 n Client4nNeeds:4nPhysiological4nIntegrity:4nPharmacological4nand4nParenteral4nT
herapi4nes4nTOP:
Chapter:4n1:4nThe4nFoundation4nof4nPharmacology:4 n Quality4nand4 n Safety
4 n KEY:4 n Integrated4nProcess:4nNursing4nProcess
BLM:4 n 4 n Cognitive4n Level:4 n Understand NOT:4 n 4 n Multiple4 n Choice
5. The4nadministration4nof4n diphenhydramine4 n is4n regulated4n by4nwhich4 n U.S.4 n government4 n agency?
A. Public4nHealth4nService
B. Federal4nTrade4nCommission
C. Occupational4n Safety4nand4nHealth4nAdministration
D. Food4nand4nDrug Administrati
b6
on4nANS: D