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Exam (elaborations)

BIOL 351 / BIOL351 – Advanced Biology Course Material – Lecture Summary and Study Notes

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This document covers the core topics of BIOL 351, an advanced biology course focusing on in-depth biological concepts and mechanisms discussed throughout the course. It includes structured summaries and study notes designed to support exam preparation and overall understanding of the material.

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BIOL 351/ BIOL351
Course
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Institution
BIOL 351/ BIOL351
Course
BIOL 351/ BIOL351

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Uploaded on
January 20, 2026
Number of pages
55
Written in
2025/2026
Type
Exam (elaborations)
Contains
Questions & answers

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BIOL 351/ BIOL351 Final Exam
(Latest 2026/ 2027 Update) 100%
Correct | Questions & correct
Answers | Grade A


Which of the following adult structures is derived from somites?

tendons, vertebrae




Cells that become the undergo a to transition first. Fill in
the blanks.
Sclerotome, epithelial, mesenchymal




The endocardial cushion cells have important roles in heart formation. Defects in the endocardial
cushions have been associated with which of the following?
septation defects




Spondylocostal dysostosis and congenital scoliosis are examples of disruption of which of the
following genetic pathways?
Notch




Somitogenesis is a developmental process that involves multiple steps regulated by specific gene
interactions. Which of the following correctly matches the gene/factor and its action during
somitogenesis?

, BIOL 351/ BIOL351 Final Exam
(Latest 2026/ 2027 Update) 100%
Correct | Questions & correct
Answers | Grade A
FGF8/Wnt3a and retinoic acid, location of the determination front




Which of the following tissues is derived from the paraxial mesoderm?
dermomyotome, syndetome, sclerotome




Which of the following is the correct order of the neural tube defects from least to most severe?

spina bifida occulta, myelomeningocele, anecephaly




Situs inversus is a rare genetic condition where the normally asymmetric localization of internal
organs is inverted. A mutation in which of the following genes is most likely linked to this
condition?
Dnah11 - a cytoskeletal component that regulates cilia motility




The long axis of the neural tube runs along which axis?

rostral-caudal




The neural tube is derived which of the following germ layers?
ectoderm

, BIOL 351/ BIOL351 Final Exam
(Latest 2026/ 2027 Update) 100%
Correct | Questions & correct
Answers | Grade A


Dorsal-ventral specification of the neural tube is regulated by secretion of which of the
following?

BMP4/7 from the roof plate (dorsal) / Shh from the notochord (ventral)




The developing human gastrula is patterned along the anterior-posterior axis by a number of
secreted cues. The anterior visceral endoderm migrates from the tip and secretes Wnt
antagonists that direct appropriate patterning along the axis.

distal, anterior-posterior




Which of the following structures is NOT derived from the epiblast in a human embryo?


a. trophoblast

b. mesoderm

c. ectoderm

d. endoderm
trophoblast




Melanocytes are derived from which embryonic tissue?

, BIOL 351/ BIOL351 Final Exam
(Latest 2026/ 2027 Update) 100%
Correct | Questions & correct
Answers | Grade A
neural crest




Whichocytoskeletalocomponentoisoparticularlyoenrichedoinotheoshaftoofoaogrowingoaxon?omicrotubule
s




Neuralocrestoisoformedowhenocellsofromotheo
regionoofotheoneuralotubeochangeoshapeofromo too morphology.
dorsal,oepithelial,omesenchymal




Whichoofotheofollowingodisordersowouldoresultsofromoembryonicoexposureotoocyclopamine,oanoinhib
itoroofoSHHosignaling?
cyclopia




Theosegmentaloorganizationoofoperipheralonervesoinotheospinalocordodependsoheavilyoupon
.

Ephrinomediatedorepulsionoofoneuralocrestoandoaxonsofromotheocaudalosomite




AolackoofoSchwannocellsoandotheoabsenceoofomajoronerveoclusters,osuchoasotheosympatheticoganglia,o
mostolikelyoresultedofromodefectsoinowhichoofotheofollowingocellotypes?
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