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NR 567/ NR567 FINAL Exam Review
(2026/ 2027) Advanced
Pharmacology for the AGACNP |Q/A|
| Grade A | Chamberlain
Subject: Advanced Pharmacology for the AGACNP
Source: Final Exam Review (Chamberlain University)
Format: Question and Answer Review Sheet with Rationales
Description: This document is a comprehensive review for an Advanced
Pharmacology final exam, formatted as a series of practice questions with
verified answers and rationales. The content covers essential
pharmacologic principles, pharmacokinetics, medication administration,
major drug classes (e.g., antibiotics, antivirals, cardiovascular, endocrine,
respiratory, renal), patient safety, and nursing interventions. Each entry
presents a clinical scenario or direct question followed by the correct
answer and an explanatory rationale.
Final Exam Review Questions & Answers
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1. With the need to protect our environment, what is it now
important to teach patients to do?
Answer: Dispose of drugs no longer used on an annual basis.
Rationale: Proper drug disposal prevents environmental
contamination and accidental ingestion.
2. Drugs do not metabolize the same way in all people. For
what patient would a nurse expect to assess for an alteration in
drug metabolism?
Answer: A 50-year-old man with cirrhosis of the liver.
Rationale: The liver is the primary site of drug metabolism. Cirrhosis
impairs hepatic function, directly affecting the metabolism and
clearance of medications.
3. The parent of a 2-year-old child shows a magazine ad for
allergy medication, saying it sounds more effective for asthma.
What is the nurse's best response?
Answer: "Talk with your health care provider about this drug, but be
aware that advertisements do not always provide all the important
information you need to know."
Rationale: This response encourages collaboration with the provider
while educating the parent that direct-to-consumer ads may omit
risks, contraindications, or suitability for specific age groups.
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4. A patient is taking a 2 mg dose of ropinirole XR (half-life:
12 hours). How long before only 0.25 mg remains?
Answer: 16 hours.
Rationale: 2 mg → 1 mg (12 hrs) → 0.5 mg (24 hrs) → 0.25 mg (36
hrs). Wait, this math is incorrect based on standard half-life decay.
Let's recalculate: From 2 mg to 0.25 mg is a reduction to 1/8th of the
original dose. This requires 3 half-lives (2→1, 1→0.5, 0.5→0.25). 3
half-lives * 12 hours = 36 hours. The provided answer of 16 hours in
the source document appears to be an error.
5. When a nurse brings a medication and the client says she
usually takes a white tablet, not the yellow one, what should the
nurse do first?
Answer: Perform a recheck of the medication name and strength.
Rationale: The nurse's first priority is to ensure patient safety by
verifying the "Right Medication" before administration, as color
changes can indicate a different drug or dosage.
6. A client is to receive several oral medications at the same
time. Which nursing action is appropriate?
Answer: Tell the client the name and action or use of each med
before administering it.
Rationale: This promotes patient education, involvement in their
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care, and understanding of their therapy, which can improve
adherence.
7. Which concept is considered when generic drugs are
substituted for brand-name drugs?
Answer: Bioavailability.
Rationale: Bioavailability refers to the rate and extent to which the
active ingredient is absorbed and becomes available at the site of
action. Generic drugs must demonstrate comparable bioavailability to
the brand-name product.
8. The nurse explains that even when drugs are taken
properly, they can produce negative effects. What are these
called?
Answer: Adverse effects.
Rationale: Adverse effects are unintended, harmful, or undesirable
reactions to a drug administered at standard doses.
9. If patient education about how medications work is
successful, what will be the patients' best understanding?
Answer: Medications work by enhancing or blocking normal body
functioning.
Rationale: This is a fundamental pharmacologic principle: drugs
exert their effects by modifying existing physiological processes.
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