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1. absorption Answer: movement of the drug from the site of administration into the blood
2. distribution Answer: movement of the drug from the blood to the site of action or storage ar
3. metabolism Answer: enzymatic breakdown of a drug into a metabolite
4. excretion Answer: removal of the drug or metabolite from the body
5. 4 basic pharmacokinetic processes Answer: absorption, distribution, metabolism,
excretion
6. routes of drug administration Answer: enteral and parenteral
7. enteral Answer: oral, sublingual, buccal, rectal
8. parenteral Answer: IV, IM, sub q
9. mechanism of passage across membrane Answer: passive dittusion; method
used by most drugs
10. passive diffusion Answer: drug concentration moves from area of higher drug
concentration to area of lower concentration
11. absorption depends on... Answer: disintegration and dissolution
12. disintegration Answer: tablet begins to break apart
13. dissolution Answer: powder mixes with stomach fluid into a solution or liquid
14. acid is a proton donor Answer: tends to ionize in basic (alkaline) media
15. base is a proton acceptor Answer: tends to ionize in acidic media
16. ionization Answer: acid giving up a proton or base accepting a proton causes the acid
or base to become a charged particle or ion
17. acid drug in base environment of intestine Answer: ionized, water soluble,
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