, Test Bank cn
to accompany
cn
Psychopharmacology, Third Edition cn cn
Meyer • Quenzer cn cn
Chapter 1: Principles of Pharmacology cn cn cn cn
Multiple Choice cn
1. cn
refer(s) to specific molecular changes that occur when a drug binds to a particular tar
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get site or receptor, while
cn cn cn cn
are the resulting widespread alterationsin function.
cn cn cn cn cn cn
a. Drug action; therapeutic effectscn cn cn
b. Side effects; drug effects cn cn cn
c. Therapeutic effects; side effects cn cn cn
d. Drug action; drug effects cn cn cn
Answer: d cn
Textbook Reference: Pharmacology: The Science of Drug Action
cn cn cn cn cn cn cn
2. After drug administration has occurred, the amount of drug in the blood that is free to
cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn
bind at specific target sites is referred to as
cn cn cn cn cn cn cn cn
a. the therapeutic dose.
cn cn
b. first-pass effects. cn
c. bioavailability.
d. ED50.
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
3. The specific molecular changes that occur when a drug binds to a particular target site
cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn
or receptor are referred to as
cn cn cn cn cn
a. drug effects. cn
b. drug action. cn
c. side effects. cn
d. placebo effects. cn
Answer: b cn
Textbook Reference: Pharmacology: The Science of Drug Action
cn cn cn cn cn cn cn
4. Which of the following is not a possible explanation for placebo effects?
cn cn cn cn cn cn cn cn cn cn cn
a. Pavlovian conditioning cn
b. Genetic variation cn
c. Drug competition cn
d. Expectation of outcome cn cn
Answer: c cn
Textbook Reference: Pharmacology: The Science of Drug Action
cn cn cn cn cn cn cn
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Page 1 of 247
cn cn cn
,5. The administration of oxytocin has been proposed as a treatment for autism. cn cn cn cn cn cn cn cn cn cn
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
6. Which factor does not affect the pharmacokinetics of a drug?
cn cn cn cn cn cn cn cn cn
a. Route of administration
cn cn
b. Lipid solubility
cn
c. Depot binding cn
d. Drug action cn
Answer: d cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
7. First-pass metabolism occurs when drugs are taken
cn cn cn cn cn cn
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
8. The area postrema is one area in the brain where the
cn cn is not complete. cn cn cn cn cn cn cn cn cn cn
a. cerebrospinal fluid cn
b. blood–brain barrier cn
c. choroid plexus cn
d. phospholipid membrane cn
Answer: b cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
9. First-pass metabolism occurs with orally administered drugs because
cn cn cn cn cn cn cn
a. their absorption is slowed by food.
cn cn cn cn cn
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way to
cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn
general circulation.
cn
c. drugs must first survive the acidic environment of the stomach.
cn cn cn cn cn cn cn cn cn
d. salivary enzymes in the mouth begin the process of metabolism.
cn cn cn cn cn cn cn cn cn
Answer: b cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
10. Toxic substances in the blood trigger a vomiting response by activating the
cn cn cn cn cn cn cn cn cn cn cn
a. blood–brain barrier. cn
b. choroid plexus. cn
c. area postrema.
cn
d. median eminence. cn
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Page 2 of 247
cn cn cn
, Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
11. Drugs administered _ have the most rapid onset of action.
cn cn cn cn cn cn cn cn
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
12. Ionization of a drug depends on the of the solution and the
cn cn cn cn cn cn cn cn cn cn
of thedrug.
cn cn
a. pH; pKa
cn
b. pKa; pH cn
c. concentration; lipid solubility cn cn
d. pH; concentration
cn
Answer: a cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
13. The absorption of a drug depends on all of the following except
cn cn cn cn cn cn cn cn cn cn cn
a. lipid solubility.
cn
b. ionization.
c. body temperature.
cn
d. the concentration of the drug.
cn cn cn cn
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
14. Drugs that are should be avoided by women of childbearing age.
cn cn cn cn cn cn cn cn cn
a. teratogenic
b. able to cross the placental barrier
cn cn cn cn cn
c. psychoactive
d. highly lipid-soluble cn
Answer: a cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
15. Agents that induce developmental abnormalities in a fetus are known as
cn cn cn cn cn cn cn cn cn cn
a. psychoactive drugs. cn
b. illicit drugs. cn
c. teratogens.
d. placental drugs. cn
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
16. Depot binding is said to occur when drugs
cn cn cn cn cn cn cn
a. bind to their target sites.
cn cn cn cn
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cn cn cn
to accompany
cn
Psychopharmacology, Third Edition cn cn
Meyer • Quenzer cn cn
Chapter 1: Principles of Pharmacology cn cn cn cn
Multiple Choice cn
1. cn
refer(s) to specific molecular changes that occur when a drug binds to a particular tar
cn cn cn cn cn cn cn cn cn cn cn cn cn cn
get site or receptor, while
cn cn cn cn
are the resulting widespread alterationsin function.
cn cn cn cn cn cn
a. Drug action; therapeutic effectscn cn cn
b. Side effects; drug effects cn cn cn
c. Therapeutic effects; side effects cn cn cn
d. Drug action; drug effects cn cn cn
Answer: d cn
Textbook Reference: Pharmacology: The Science of Drug Action
cn cn cn cn cn cn cn
2. After drug administration has occurred, the amount of drug in the blood that is free to
cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn
bind at specific target sites is referred to as
cn cn cn cn cn cn cn cn
a. the therapeutic dose.
cn cn
b. first-pass effects. cn
c. bioavailability.
d. ED50.
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
3. The specific molecular changes that occur when a drug binds to a particular target site
cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn
or receptor are referred to as
cn cn cn cn cn
a. drug effects. cn
b. drug action. cn
c. side effects. cn
d. placebo effects. cn
Answer: b cn
Textbook Reference: Pharmacology: The Science of Drug Action
cn cn cn cn cn cn cn
4. Which of the following is not a possible explanation for placebo effects?
cn cn cn cn cn cn cn cn cn cn cn
a. Pavlovian conditioning cn
b. Genetic variation cn
c. Drug competition cn
d. Expectation of outcome cn cn
Answer: c cn
Textbook Reference: Pharmacology: The Science of Drug Action
cn cn cn cn cn cn cn
WWW.THENURSINGMASTERY.COM
Page 1 of 247
cn cn cn
,5. The administration of oxytocin has been proposed as a treatment for autism. cn cn cn cn cn cn cn cn cn cn
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
6. Which factor does not affect the pharmacokinetics of a drug?
cn cn cn cn cn cn cn cn cn
a. Route of administration
cn cn
b. Lipid solubility
cn
c. Depot binding cn
d. Drug action cn
Answer: d cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
7. First-pass metabolism occurs when drugs are taken
cn cn cn cn cn cn
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
8. The area postrema is one area in the brain where the
cn cn is not complete. cn cn cn cn cn cn cn cn cn cn
a. cerebrospinal fluid cn
b. blood–brain barrier cn
c. choroid plexus cn
d. phospholipid membrane cn
Answer: b cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
9. First-pass metabolism occurs with orally administered drugs because
cn cn cn cn cn cn cn
a. their absorption is slowed by food.
cn cn cn cn cn
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way to
cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn cn
general circulation.
cn
c. drugs must first survive the acidic environment of the stomach.
cn cn cn cn cn cn cn cn cn
d. salivary enzymes in the mouth begin the process of metabolism.
cn cn cn cn cn cn cn cn cn
Answer: b cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
10. Toxic substances in the blood trigger a vomiting response by activating the
cn cn cn cn cn cn cn cn cn cn cn
a. blood–brain barrier. cn
b. choroid plexus. cn
c. area postrema.
cn
d. median eminence. cn
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Page 2 of 247
cn cn cn
, Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
11. Drugs administered _ have the most rapid onset of action.
cn cn cn cn cn cn cn cn
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
12. Ionization of a drug depends on the of the solution and the
cn cn cn cn cn cn cn cn cn cn
of thedrug.
cn cn
a. pH; pKa
cn
b. pKa; pH cn
c. concentration; lipid solubility cn cn
d. pH; concentration
cn
Answer: a cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
13. The absorption of a drug depends on all of the following except
cn cn cn cn cn cn cn cn cn cn cn
a. lipid solubility.
cn
b. ionization.
c. body temperature.
cn
d. the concentration of the drug.
cn cn cn cn
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
14. Drugs that are should be avoided by women of childbearing age.
cn cn cn cn cn cn cn cn cn
a. teratogenic
b. able to cross the placental barrier
cn cn cn cn cn
c. psychoactive
d. highly lipid-soluble cn
Answer: a cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
15. Agents that induce developmental abnormalities in a fetus are known as
cn cn cn cn cn cn cn cn cn cn
a. psychoactive drugs. cn
b. illicit drugs. cn
c. teratogens.
d. placental drugs. cn
Answer: c cn
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
cn cn cn cn cn cn
16. Depot binding is said to occur when drugs
cn cn cn cn cn cn cn
a. bind to their target sites.
cn cn cn cn
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cn cn cn
