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Clinical Medicine I (Clin Med I) – Diabetes Q&A (125 Questions) | 2025 | Types, Treatment, Complications

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This document offers 125 expert-verified practice questions and answers for the Clinical Medicine I (Clin Med I) course, specifically centered on Diabetes Mellitus. It comprehensively covers the pathophysiology, diagnosis, and management of Type 1 and Type 2 diabetes, as well as gestational diabetes and T3DM. Core topics include insulin resistance, β-cell dysfunction, hyperglycemia and hypoglycemia, diabetic ketoacidosis (DKA), and chronic complications such as neuropathy, retinopathy, foot ulcers, and cardiovascular disease. Additionally, the document reviews pharmacologic treatments like biguanides (metformin), sulfonylureas, GLP-1 analogs, and more, along with lab testing protocols such as HbA1c and oral glucose tolerance testing (OGTT). Presented in a clear Q&A format, this resource is tailored for medical students, nursing students, physician associate/assistant programs, and learners in clinical healthcare education. It serves as a reliable tool for exam prep, concept reinforcement, and clinical application. Keywords: T1DM, T2DM, DKA, insulin resistance, β-cell dysfunction, gestational diabetes, HbA1c, neuropathy, retinopathy, metformin, sulfonylureas, GLP-1, hypoglycemia, hyperglycemia, foot ulcers, diabetic complications, diabetes treatment, glucose metabolism, clinical medicine, medical Q&A

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Institution
Clinical Medicine
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Clinical Medicine

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Uploaded on
December 22, 2025
Number of pages
12
Written in
2025/2026
Type
Exam (elaborations)
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Questions & answers

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Clin Med I: Diabetes 2025 Expert Verified
| Ace the Test



Type of DM with acute onset - 🧠 ANSWER ✔✔T1DM


Type of DM with delayed onset - 🧠 ANSWER ✔✔T2DM


Type of DM with weight loss - 🧠 ANSWER ✔✔T1DM


Type of DM with weight gain - 🧠 ANSWER ✔✔T2DM


Type of DM with β-cell destruction. - 🧠 ANSWER ✔✔T1DM


Type of DM with β-cell dysfunction. - 🧠 ANSWER ✔✔T2DM


DM with strong HLA association - 🧠 ANSWER ✔✔T1DM


Most common DM - 🧠 ANSWER ✔✔T2DM

, Type of DM with unrestrained lipolysis? - 🧠 ANSWER ✔✔T1DM (think

DKA) (different in PPT, need to check)


Which DM is insulin dependent? Why? - 🧠 ANSWER ✔✔T1DM. The β-cells

that produce insulin are destroyed.


Which DM is insulin resistant? Why? - 🧠 ANSWER ✔✔T2DM. Insulin

receptors on adipose tissue are absent or insensitive to insulin.


What is T3DM? - 🧠 ANSWER ✔✔T1DM with later obesity, insulin

resistance, and metabolic syndrome.


What's the hepatic response in T2DM? - 🧠 ANSWER ✔✔Increased

gluconeogenesis and decreased glycogenesis.


What's the gastric response in T2DM? - 🧠 ANSWER ✔✔Gastric dysmotility

and increased glucose absorption.

Metabolism of what macromolecules are disturbed in DM? - 🧠 ANSWER

✔✔Carbohydrates, lipids and proteins. (NOT JUST CARB/GLUCOSE)


Charcot neuroarthropathy - 🧠 ANSWER ✔✔Bone and joint changes that

occur secondary to loss of sensation that include dislocation and

degenerative changes.

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