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MCAT101 CHEMISTRY/PHYSIOLOGY – AAMC FL2 (59 Questions) | Expert-Verified MCQ Explanations | Ace the Test

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This advanced MCAT prep document presents 59 expert-verified multiple-choice questions (MCQs) from the AAMC Full-Length Practice Test 2 (FL2), specifically targeting the Chemistry and Biology/Physiology sections for the 2025 MCAT format. Designed to match AAMC’s passage-based style and conceptual reasoning approach, each question includes a clear and insightful explanation that breaks down not only the correct answer but also key MCAT strategies and underlying scientific concepts. Topics covered include: Venturi and Bernoulli fluid principles Acid-base chemistry, buffers, and pH/pKa calculations Equilibrium constants, solubility product (Ksp), and Le Châtelier’s principle Thermodynamics and kinetics: ΔG, enthalpy, entropy, and rate laws Redox reactions, electrochemical cells, and hybridization Gas laws, atomic structure, ionization energies, and bond polarity Biological macromolecules, protein folding, and gene expression Hormonal regulation, metabolism (glycolysis, PPP, CAC), and renal function MCAT-relevant lab interpretations, physiological measurements (e.g., blood pressure, ATP production), and cellular processes (e.g., endocytosis, proteolysis) This document is particularly suitable for students pursuing pre-medical, biochemistry, life sciences, biomedical sciences, molecular biology, or health sciences degrees. It aligns closely with university courses such as CHEM200 (General Chemistry), BIOC300 (Biochemistry), PHYS150 (Physics for Life Sciences), and PSL302 (Human Physiology). Universities with strong MCAT and health science preparation programs—such as the University of Toronto, McMaster University, UCLA, or University of Michigan—will find this material highly aligned with their academic standards and test prep rigor. Keywords: MCAT, AAMC FL2, chemistry, biology, physiology, buffer, equilibrium, Ksp, redox, fluid dynamics, gene expression, pKa, electrochemistry, solubility, protein structure, renal system, hormonal feedback, reaction kinetics, MCQ explanations, university prep

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MCAT101 AAMC FL2 Chemistry & Biology
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MCAT101 AAMC FL2 Chemistry & Biology
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MCAT101 AAMC FL2 Chemistry & Biology

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Uploaded on
December 22, 2025
Number of pages
53
Written in
2025/2026
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MCAT101 AAMC FL2 Chemistry &
Biology 2025 Expert Verified | Ace the
Test



Venturi pressure effect (summation) - 🧠ANSWER ✔✔-(+) volume, (+)

pressure

-small diameter, small pressure (less summation effect)

-venturi bags used for COPD

-fluid pressure inverse of velocity

(p v=p v)

,*PV=nRT does not apply here since it's water NOT GAS. Since a pipe is an

enclosed system with water of equal density; pressure is deter by total

particles not density.




*NOT diffusion which is down a CONCENTRATION gradient. this is down a

pressure difference


Bernouli water effect (pooling) - 🧠ANSWER ✔✔(-) velocity, (+) pressure or

pooling

-at the narrowest part there's less pooling so has lowest pressure, but most

speed




*the water just want to zip through the narrowing as quickly as possible.

This aligns with Venturi effect since smaller diameter means less total

particles, less pressure restriction, faster get through

What causes duplex DNA with a certain (A + T):(G + C) ratio to melt at a

higher temperature than comparable length duplex DNA with a greater (A +

T):(G + C) ratio?

,A.

Stronger van der Waals forces of pyrimidines




B.

Stronger van der Waals forces of purines




C.

Increased π- stacking strength




D.


Reduced electrostatic repulsion of phosphates - 🧠ANSWER ✔✔C.


Increased π- stacking strength




less AT to GC means GC (denominator) is higher. G≡C is a triple H bond

with pi stacking strength

(H--->O, H--->N, O<--H)



COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED

, *HO, HH, OH

Which property of a substance is best used to estimate its relative vapor

pressure?




A.

Melting point




B.

Boiling point




C.

Molecular weight




D.


Dipole moment - 🧠ANSWER ✔✔B.

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