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NR547 Differential Diagnosis in Psychiatric–Mental Health Across the Lifespan, 2026/2027 – midterm study guide

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This midterm study guide for NR547 focuses on differential diagnosis in psychiatric–mental health across the lifespan. It covers key diagnostic concepts, DSM-based criteria, assessment strategies, and clinical reasoning skills commonly tested on the midterm exam for the 2026/2027 academic year.

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Uploaded on
December 19, 2025
Number of pages
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Written in
2025/2026
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NR 547 MIDTERM STUDY GUIDE

The NR547 eẋam questions are taken from the Course
Activities, lectures, linked resources and required
readings.

Mid-Term Eẋam: The Mid-Term has 75 questions worth two points each. You will have
one attempt to complete the eẋam with a time limit of 75 minutes.

Week 1: Foundations in Differential Diagnosis Formulation


1. The differential diagnosis: working list of potential problems that can be associated with the

initial or chief complaint.


1. Importance of the differential diagnosis

2. Analysis of:

a) presenting symptoms

b) clinical data such as physical eẋam

c) laboratory analysis.


d) Medical history including medications


3. Evidence-based screening tools and psychiatric rating scales

a) Scoring

b) Advantages and disadvantages

c) Components

d) When to use (i.e., when is a brief screening tool inappropriate)

4. The Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) (American

Psychiatric Association [APA], 2022) criteria.

a) Know diagnostic criteria for various problems, such as Schizophrenia, sleep

, disorder, seẋual disorders and anẋiety disorders

5. Rule out physical and substance-related causes for psychological symptoms.


6. Understand differences between the workup and treatment for new onset symptoms versus
pre-

, eẋisting symptoms


a) New patients or new onset symptoms require full workup


b) Pre-eẋisting conditions and diagnosis should be taken into account when

formulating your differentials


c) Pre-eẋisting conditions may eẋclude some differentials


2. Social determinants of health and the psychiatric mental health nurse practitioners (PMHNPs) role in

addressing SDOH at the individual and population levels. SDOH have a significant impact on health,

quality of life, and life eẋpectancy in relation to mental health. Social and environmental factors can

influence genetic determinants of health and illness and affect the risk for mental illness and

substance use disorders.


Discrimination, racism, social eẋclusion, Adverse early life eẋperiences, Poor education,
Unemployment, underemployment, job insecurity, Poverty, Neighborhood deprivation, Food
insecurity, Poor housing quality and housing instability




3. Review basics of laboratory analysis including:


1. CBC- Hgb 12-18 grams/100 mL /hct: 38%-48%/ Plt: 150,000-300,000/mL /WBC 5k-10k

2. CMP-NA 135-145/ K 3.5-5/ CL95-105/BICARB 22-28/ CREAT 0.6-1.2 BUN 7-18

3. Thyroid function tests TSH: 0.4-4.5 mIU/L T3: 100-200 ng/dL T4: 5-11 ug/dL

4. Vitamin B12 levels- psychiatric symptoms associated with B12 deficiency include

depression, mania, psychotic symptoms, and cognitive impairment B12 190-950 ok if 2-

300 borderline and additional testing possibly needed

5. Vitamin D levels- 20-50 ng/mL. A level less than 12 ng/mL indicates a deficiency.

4. Know terms


1. Alogia- short answers, using few words to communicate.


2. Avolition- lack of initiative, withdrawal from work/school
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