12/17/25, 3:38 PM APHON Principles of Chemo and Biotherapy Exam fully solved & updated 2025-2026(latest version verified for accuracy) | 2024\2…
APHON Principles of Chemo and Biotherapy
Exam fully solved & updated 2025-2026(latest
version verified for accuracy) | 2024\2025Latest!!
Save
Terms in this set (56)
Targeted anticancer agents also known as biological
Biotherapy
response modifiers (BRM)
Tyrosine kinase inhibitors Biotherapy
(TKIs) are what class
Monoclonal antibodies Biotherapy
(MoAbs) are what class
Define pharmacokinetics Study of drug absorption, metabolism, and excretion
Define The concentration of the drug in the body and how it
pharmacodynamics produces a response
The use of chemo after another type of therapy, such
Define adjuvant
as surgery, to treat residual disease or undetectable
chemotherapy
metastasis.
When chemo is used preoperatively to decrease
Define neoadjuvant
tumor burden in order to make it easier to remove the
chemotherapy
tumor surgically.
Sites within the body where tumor cells sequester and
Define sanctuary sites
are not easily reached by chemo such as the CNS
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, 12/17/25, 3:38 PM APHON Principles of Chemo and Biotherapy Exam fully solved & updated 2025-2026(latest version verified for accuracy) | 2024\2…
What normal cells are Hematopoietic, mucosal (mouth & GI), hair follicles
most often effected by
chemotherapy
To prevent cancer cells from dividing, metastasizing,
Why use chemotherapy
and ultimately causing the death of the patient
Cure To permanently eradicate the cancer
To extend the length & QOL when cure is not feasible
Control
or realistic
Palliation Minimize pain and suffering during end of life
Resting phase of cell Gap 0 - cells not dividing
cycle
Gap 1 - enzymes needed for DNA synthesis are
Postmitotic phase produced, protein and RNA synthesis takes place (18
Hours)
Synthesis (S) Phase Cellular DNA duplicated (20 hours)
Gap 2 - both protein and RNA synthesis occur,
Premitotic phase precursors of mitotic spindle are produced. Shortest
phase
Cell division occurs in 4-step phase (prophase,
Mitosis (M) Phase
metaphase, anaphase, telophase) 1 Hour
5 stages of reproduction Resting, Postmitotic, synthesis, premitotic, mitosis
of cells
The amount of time it takes a cell to move from one
Cell Cycle time
mitotic episode to another.
Those drugs that work only when cells are in a
Cell-cycle-specific agents
specific phase of the cell cycle.
The time required for a tumor mass to reach a certain
Doubling time
size or double in size.
Percentage of cells actively dividing at any given
Growth fraction
point in time.
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APHON Principles of Chemo and Biotherapy
Exam fully solved & updated 2025-2026(latest
version verified for accuracy) | 2024\2025Latest!!
Save
Terms in this set (56)
Targeted anticancer agents also known as biological
Biotherapy
response modifiers (BRM)
Tyrosine kinase inhibitors Biotherapy
(TKIs) are what class
Monoclonal antibodies Biotherapy
(MoAbs) are what class
Define pharmacokinetics Study of drug absorption, metabolism, and excretion
Define The concentration of the drug in the body and how it
pharmacodynamics produces a response
The use of chemo after another type of therapy, such
Define adjuvant
as surgery, to treat residual disease or undetectable
chemotherapy
metastasis.
When chemo is used preoperatively to decrease
Define neoadjuvant
tumor burden in order to make it easier to remove the
chemotherapy
tumor surgically.
Sites within the body where tumor cells sequester and
Define sanctuary sites
are not easily reached by chemo such as the CNS
https://quizlet.com/1124081927/aphon-principles-of-chemo-and-biotherapy-exam-fully-solved-updated-2025-2026latest-version-verified-for-accuracy-2… 1/6
, 12/17/25, 3:38 PM APHON Principles of Chemo and Biotherapy Exam fully solved & updated 2025-2026(latest version verified for accuracy) | 2024\2…
What normal cells are Hematopoietic, mucosal (mouth & GI), hair follicles
most often effected by
chemotherapy
To prevent cancer cells from dividing, metastasizing,
Why use chemotherapy
and ultimately causing the death of the patient
Cure To permanently eradicate the cancer
To extend the length & QOL when cure is not feasible
Control
or realistic
Palliation Minimize pain and suffering during end of life
Resting phase of cell Gap 0 - cells not dividing
cycle
Gap 1 - enzymes needed for DNA synthesis are
Postmitotic phase produced, protein and RNA synthesis takes place (18
Hours)
Synthesis (S) Phase Cellular DNA duplicated (20 hours)
Gap 2 - both protein and RNA synthesis occur,
Premitotic phase precursors of mitotic spindle are produced. Shortest
phase
Cell division occurs in 4-step phase (prophase,
Mitosis (M) Phase
metaphase, anaphase, telophase) 1 Hour
5 stages of reproduction Resting, Postmitotic, synthesis, premitotic, mitosis
of cells
The amount of time it takes a cell to move from one
Cell Cycle time
mitotic episode to another.
Those drugs that work only when cells are in a
Cell-cycle-specific agents
specific phase of the cell cycle.
The time required for a tumor mass to reach a certain
Doubling time
size or double in size.
Percentage of cells actively dividing at any given
Growth fraction
point in time.
https://quizlet.com/1124081927/aphon-principles-of-chemo-and-biotherapy-exam-fully-solved-updated-2025-2026latest-version-verified-for-accuracy-2… 2/6
