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HESI PHARMACOLOGY EXAM PRACTICE ACTUAL EXAM COMPLETE 1050 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES| LATEST // ALREADY GRADED A+

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HESI PHARMACOLOGY EXAM PRACTICE ACTUAL EXAM COMPLETE 1050 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES| LATEST // ALREADY GRADED A+

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HESI PHARMACOLOGY PRACTICE
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Uploaded on
December 12, 2025
Number of pages
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Written in
2025/2026
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HESI PHARMACOLOGY EXAM PRACTICE
ACTUAL EXAM COMPLETE 1050
QUESTIONS AND CORRECT DETAILED
ANSWERS WITH RATIONALES| LATEST
2024-2025 // ALREADY GRADED A+




A healthcare provider prescribes cephalexin monohydrate
(Keflex) for a client with a postoperative infection. It is most
important for the nurse to assess for what additional drug
allergy before administering this prescription?

A) Penicillins.

B) Aminoglycosides.

C) Erythromycins.

D) Sulfonamides. - CORRECT ANSWER-A) Penicillins.



Cross-allergies exist between penicillins (A) and
cephalosporins, such as cephalexin monohydrate (Keflex), so

,checking for penicillin allergy is a wise precaution before
administering this drug.



Which nursing intervention is most important when caring for
a client receiving the antimetabolite cytosine arabinoside
(Arc-C) for chemotherapy?

A) Hydrate the client with IV fluids before and after
infusion.

B) Assess the client for numbness and tingling of extremities.

C) Inspect the client's oral mucosa for ulcerations.

D) Monitor the client's urine pH for increased acidity. -
CORRECT ANSWER-C) Inspect the client's oral mucosa for
ulcerations.



Cytosine arabinoside (Arc-C) affects the rapidly growing cells
of the body, therefore stomatitis and mucosal ulcerations are
key signs of antimetabolite toxicity (C). (A, B, and D) are not
typical interventions associated with the administration of
antimetabolites.

,When assessing an adolescent who recently overdosed on
acetaminophen (Tylenol), it is most important for the nurse to
assess for pain in which area of the body?

A) Flank.

B) Abdomen.

C) Chest.

D) Head. - CORRECT ANSWER-B) Abdomen.



Acetaminophen toxicity can result in liver damage; therefore,
it is especially important for the nurse to assess for pain in
the right upper quadrant of the abdomen (B), which might
indicate liver damage. (A, C, and D) are not areas where pain
would be anticipated.



An adult client is given a prescription for a scopolamine patch
(Transderm Scop) to prevent motion sickness while on a
cruise. Which information should the nurse provide to the
client?

A) Apply the patch at least 4 hours prior to departure.

B) Change the patch every other day while on the cruise.

C) Place the patch on a hairless area at the base of the skull.

, D) Drink no more than 2 alcoholic drinks during the cruise. -
CORRECT ANSWER-A) Apply the patch at least 4 hours
prior to departure.



Scopolamine, an anticholinergic agent, is used to prevent
motion sickness and has a peak onset in 6 hours, so the client
should be instructed to apply the patch at least 4 hours
before departure (A) on the cruise ship. The duration of the
transdermal patch is 72 hours, so (B) is not needed.
Scolopamine blocks muscarinic receptors in the inner ear and
to the vomiting center, so the best application site of the
patch is behind the ear, not at the base of the skull (C).
Anticholinergic medications are CNS depressants, so the
client should be instructed to avoid alcohol (D) while using the
patch.



The nurse is reviewing the use of the patient-controlled
analgesia (PCA) pump with a client in the immediate
postoperative period. The client will receive morphine 1 mg IV
per hour basal rate with 1 mg IV every 15 minutes per PCA to
total 5 mg IV maximally per hour. What assessment has the
highest priority before initiating the PCA pump?

A) The expiration date on the morphine syringe in the pump.

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