1. The study of drug absorption, distribution, metabolism, and excretion is known as
A. Pharmacotherapeutics
B. Pharmacodynamics
C. Pharmacokinetics
D. Pharmacy
E. Posology - correct answer C
2. The medical situation when a particular drug should not be administered is referred to
as
A. Side effect
B. Adverse effect
C. Drug allergy
D. Contraindication
E. Antagonism - correct answer D
3. An unusual or unexpected drug reaction by an individual is known as
A. Toxic effect
B. Antagonism
C. Idiosyncrasy
D. Side effect
E. Drug allergy - correct answer C
4. The proprietary drug name supplied by a pharmaceutical company is also referred to
as the
A. Generic name
B. Over-the-counter name
C. Trade name
D. Chemical name
E. None of these - correct answer C
5. The time from drug administration to the first observable drug effect is known as the
A. Duration of action
B. Onset of action
C. Ceiling effect
D. Maximal response
E. Ceiling effect - correct answer B
6. A drug that has the potential for abuse and is regulated by the Drug Enforcement
Agency is classified as a
A. Poison
B. OTC drug
C. Prescription drug
D. Controlled substance
E. Nonproprietary drug - correct answer D
,7. Select the term below that relates to the amount of drug administered to produce a
therapeutic effect.
A. Posology
B. Toxicology
C. Pharmacodynamics
D. Pharmacotherapeutics
E. Pharmacy - correct answer A
8. A medication that does not require a physician's service to obtain is referred to as
A. Trade
B. Nonproprietary
C. Nonprescription
D. Brand
E. Generic - correct answer C
9. Which of the following could be categorized as an adverse reaction?
A. Idiosyncrasy
B. Drug allergy
C. Teratogenicity
D. Carcinogenicity
E. All of these - correct answer E
10. The time a drug continues to produce its effect is its
A. ED50
B. Maximal response
C. Ceiling effect
D. Onset of action
E. Duration of action - correct answer E
. The drug administration route demonstrating the slowest onset of action is
A. Inhalation
B. Transdermal
C. Intramuscular
D. Sublingual
E. Intravenous - correct answer B
In order for drugs to cross the blood-brain barrier, they must be
A. Ionized
B. Positively charged
C. Water soluble
D. Lipid soluble
E. Negatively charged - correct answer D
13. First-pass metabolism refers to the metabolism of drugs in the
A. Kidney
, B. Blood vessels
C. Liver
D. Heart
E. Adipose tissue - correct answer C
14. Drug X has a half-life of 6 hours. How much drug is left in the body 18 hours after an
IV injection of 1200 milligrams (mg)? - correct answer B
15. Drugs that have demonstrated teratogenic effects in women are classified as
Pregnancy Category
A. B
B. C
C. D
D. X
E. NR - correct answer D= x
16. When a drug increases the rate of drug metabolism of other drugs, the process is
termed
A. First-pass metabolism
B. Enzyme induction
C. Enzyme inhibition
D. Enterohepatic cycling
E. Microsomal inhibition - correct answer B
17. The rate of drug absorption would be increased by which of the following?
A. Drug ionization
B. Water solubility
C. Positively charged drug
D. Negatively charged drug
E. Lipid solubility - correct answer E
18. Which factor of individual variation is dependent upon the patient's attitude toward
treatment?
A. Weight
B. Age
C. Genetic variation
D. Placebo effect
E. Gender - correct answer D
19. Which FDA pregnancy category would appear to be the safest for a developing
fetus?
A. Category A
B. Category B
C. Category C
D. Category D
E. Category X - correct answer A