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Criteria for choosing an effective drug for a disorder include: - CORRECT ANSWERS Consulting
nationally recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of: - CORRECT ANSWERS
The demonstrated ability of nurse practitioners to control costs and improve patient
outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to
prescribing because: - CORRECT ANSWERS Distribution of drugs to target tissue may be affected.
Nurse practitioner prescriptive authority is regulated by: - CORRECT ANSWERS The State Board of
Nursing for each state
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber
include: - CORRECT ANSWERS Nurses care for the patient from a holistic approach and include the
patient in
decision making regarding their care.
Clinical judgment in prescribing includes: - CORRECT ANSWERS Factoring in the cost to the patient of
the medication prescribed
Drugs that have a significant first-pass effect: - CORRECT ANSWERS Are rapidly metabolized by the
liver and may have little if any desired action
The route of excretion of a volatile drug will likely be the: - CORRECT ANSWERS Lungs
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs: - CORRECT ANSWERS Increase the length of time a drug is
available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's: - CORRECT
ANSWERS Biological half-life
,Adv Pharm Nur 615 Exam 1 Davis Review Questions And Answers
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6. Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of the
prescription. This is considered a loading dose. A loading dose: - CORRECT ANSWERS Rapidly
achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect
is the: - CORRECT ANSWERS Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done: - CORRECT
ANSWERS To determine if a drug is in the therapeutic range
A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration.
This means that the: - CORRECT ANSWERS Concentration will produce an adverse response
Drugs that are receptor agonists may demonstrate what property? - CORRECT ANSWERS
Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause: - CORRECT ANSWERS An
exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include: - CORRECT ANSWERS Lipid solubility of the drug
Drugs administered via IV: - CORRECT ANSWERS Begin distribution into the body immediately
When a medication is added to a regimen for a synergistic effect, the combined effect of the drugs is:
- CORRECT ANSWERS Greater than the sum of the effects of each drug individually
Which of the following statements about bioavailability is true? - CORRECT ANSWERS Bioavailability
issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
Which of the following statements about the major distribution barriers (blood-brain
, Adv Pharm Nur 615 Exam 1 Davis Review Questions And Answers
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or fetal-placental) is true? - CORRECT ANSWERS The blood-brain barrier slows the entry of many
drugs into and from brain cells.
Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both of
these types of reactions is to: - CORRECT ANSWERS Change drug molecules to a form that an
excretory organ can excrete
Once they have been metabolized by the liver, the metabolites may be: - CORRECT ANSWERS 1.
More active than the parent drug
2. Less active than the parent drug
3. Totally "deactivated" so they are excreted without any effect
4. All of the above
All drugs continue to act in the body until they are changed or excreted. The ability of the body to
excrete drugs via the renal system would be increased by: - CORRECT ANSWERS Unbinding a
nonvolatile drug from plasma proteins
Steady state is: - CORRECT ANSWERS When the amount of drug in the body remains constant
Two different pain medications are given together for pain relief. The drug—drug interaction is: -
CORRECT ANSWERS Additive
Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT: -
CORRECT ANSWERS 1. Reducing the dosage of one of the drugs
2. Scheduling their administration at different times
3. Prescribing a third drug to counteract the adverse reaction of the combination
4. Reducing the dosage of both drugs
Phase I oxidative-reductive processes of drug metabolism require certain nutritional elements.
Which of the following would reduce or inhibit this process? - CORRECT ANSWERS 1. Protein
malnutrition
2. Iron-deficiency anemia