ATI RN Comprehensive Predictor 2026 Exit Exam with NGN Questions &
Answers # 2026 RN ATI Comprehensive Predictor Exit Exam with NGN
Questions & Answers
,1. A nurse is caring for a client with a urinary tract infection who has been prescribed
ciprofloxacin. Which of the following statements by the client indicates a need for further
teaching?
A. “I will complete the entire course of this antibiotic.”
B. “I can take the medication with or without food.”
C. “I should increase my fluid intake while taking this medication.”
D. “I will take this medication with an antacid if I feel stomach upset.”
-CORRECT ANSWER >-D. “I will take this medication with an antacid if I feel
stomach upset.”
Rationale: Ciprofloxacin absorption can be significantly reduced by antacids containing
magnesium or aluminum, decreasing its effectiveness. Clients should be instructed to
take ciprofloxacin at least 2 hours before or 6 hours after taking antacids. Completing the
full course of therapy ensures eradication of the infection. The medication may be taken
with or without food to reduce gastrointestinal upset. Increasing fluid intake helps
prevent crystalluria and kidney injury. Proper education promotes effective treatment and
prevents antibiotic resistance or treatment failure.
2. A nurse is monitoring a client who is receiving vancomycin intravenously. Which of the
following findings indicates a potentially serious adverse effect?
A. Mild headache after infusion
B. Redness and flushing of the upper body
C. Serum creatinine increase from 1.0 to 1.8 mg/dL
D. Mild nausea during infusion
-CORRECT ANSWER >-C. Serum creatinine increase from 1.0 to 1.8 mg/dL
Rationale: An increase in serum creatinine indicates nephrotoxicity, a serious potential
adverse effect of vancomycin. Redness and flushing of the upper body, known as “red
man syndrome,” can occur if the infusion is given too rapidly but is usually reversible
and less dangerous. Mild headache and nausea are common side effects. Early detection
of nephrotoxicity allows prompt adjustment of dosage or discontinuation, preventing
permanent kidney damage and ensuring safe administration of vancomycin.
3. A nurse is providing education to a client with type 1 diabetes mellitus about self-
administration of insulin. Which of the following statements by the client indicates
correct understanding?
A. “I will rotate my injection sites to prevent skin problems.”
B. “I can mix long-acting insulin with rapid-acting insulin in the same syringe.”
C. “I will skip my insulin dose if I plan to eat less than usual.”
, D. “I will store my insulin in the freezer to keep it effective.”
-CORRECT ANSWER >-A. “I will rotate my injection sites to prevent skin problems.”
Rationale: Rotating injection sites prevents lipohypertrophy, which can interfere with
insulin absorption. Long-acting insulin should not be mixed with other insulins in the
same syringe, and insulin should not be skipped as this can lead to hyperglycemia or
diabetic ketoacidosis. Insulin should be stored in the refrigerator but not frozen, as
freezing damages its potency. Proper technique and storage ensure effective blood
glucose control and prevent complications.
4. A nurse is caring for a client receiving a blood transfusion. Which of the following
findings requires immediate intervention?
A. Blood pressure of 130/78 mm Hg
B. Client reports itching and hives during transfusion
C. Temperature of 37.5°C (99.5°F)
D. Urine output of 60 mL over 2 hours
-CORRECT ANSWER >-B. Client reports itching and hives during transfusion
Rationale: Itching and hives indicate a possible allergic transfusion reaction. The nurse
should immediately stop the transfusion, maintain IV access with normal saline using
new tubing, and notify the healthcare provider. Blood pressure and mild temperature
changes are expected findings and may not require intervention. Normal urine output
does not indicate a problem. Prompt recognition and management of transfusion reactions
prevent progression to anaphylaxis or other life-threatening complications.
5. A nurse is providing dietary teaching to a client with hypertension who has a new
prescription for hydrochlorothiazide. Which of the following statements indicates
understanding of the teaching?
A. “I should limit foods high in potassium like bananas and oranges.”
B. “I will increase my intake of potassium-rich foods such as potatoes and spinach.”
C. “I will avoid drinking water to prevent swelling.”
D. “I do not need to monitor my weight while taking this medication.”
-CORRECT ANSWER >-B. “I will increase my intake of potassium-rich foods such as
potatoes and spinach.”
Rationale: Hydrochlorothiazide is a thiazide diuretic that can cause potassium loss,
increasing the risk of hypokalemia. Encouraging the intake of potassium-rich foods helps
maintain electrolyte balance and prevent complications such as cardiac dysrhythmias.
Limiting potassium-rich foods is incorrect and increases risk. Clients should not restrict
water unless specifically prescribed, and monitoring weight helps assess fluid status and
, effectiveness of the medication. Proper dietary education enhances medication safety and
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therapeutic effectiveness. ZI
6. A nurse is caring for a client with a urinary tract infection who has been prescribed ciprofl
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oxacin. Which of the following statements by the client indicates a need for further teachi
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ng?
A. “I will complete the entire course of this antibiotic.”
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B. “I can take the medication with or without food.”
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C. “I should increase my fluid intake while taking this medication.”
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D. “I will take this medication with an antacid if I feel stomach upset.”
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-CORRECT ANSWER >-
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D. “I will take this medication with an antacid if I feel stomach upset.”
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Rationale: Ciprofloxacin absorption can be significantly reduced by antacids containing
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magnesium or aluminum, decreasing its effectiveness. Clients should be instructed to take
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ciprofloxacin at least 2 hours before or 6 hours after taking antacids. Completing the full
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course of therapy ensures eradication of the infection. The medication may be taken with
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or without food to reduce gastrointestinal upset. Increasing fluid intake helps prevent crys
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talluria and kidney injury. Proper education promotes effective treatment and prevents ant
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ibiotic resistance or treatment failure.
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7. A nurse is monitoring a client who is receiving vancomycin intravenously. Which of the f
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ollowing findings indicates a potentially serious adverse effect?
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A. Mild headache after infusion
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B. Redness and flushing of the upper body
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C. Serum creatinine increase from 1.0 to 1.8 mg/dL
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D. Mild nausea during infusion
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-CORRECT ANSWER >-C. Serum creatinine increase from 1.0 to 1.8 mg/dL
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Rationale: An increase in serum creatinine indicates nephrotoxicity, a serious potential ad
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verse effect of vancomycin. Redness and flushing of the upper body, known as “red man s
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yndrome,” can occur if the infusion is given too rapidly but is usually reversible and less d
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angerous. Mild headache and nausea are common side effects. Early detection of nephroto
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xicity allows prompt adjustment of dosage or discontinuation, preventing permanent kidn
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ey damage and ensuring safe administration of vancomycin.
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8. A nurse is providing education to a client with type 1 diabetes mellitus about self-
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administration of insulin. Which of the following statements by the client indicates correc
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t understanding?
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A. “I will rotate my injection sites to prevent skin problems.”
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Answers # 2026 RN ATI Comprehensive Predictor Exit Exam with NGN
Questions & Answers
,1. A nurse is caring for a client with a urinary tract infection who has been prescribed
ciprofloxacin. Which of the following statements by the client indicates a need for further
teaching?
A. “I will complete the entire course of this antibiotic.”
B. “I can take the medication with or without food.”
C. “I should increase my fluid intake while taking this medication.”
D. “I will take this medication with an antacid if I feel stomach upset.”
-CORRECT ANSWER >-D. “I will take this medication with an antacid if I feel
stomach upset.”
Rationale: Ciprofloxacin absorption can be significantly reduced by antacids containing
magnesium or aluminum, decreasing its effectiveness. Clients should be instructed to
take ciprofloxacin at least 2 hours before or 6 hours after taking antacids. Completing the
full course of therapy ensures eradication of the infection. The medication may be taken
with or without food to reduce gastrointestinal upset. Increasing fluid intake helps
prevent crystalluria and kidney injury. Proper education promotes effective treatment and
prevents antibiotic resistance or treatment failure.
2. A nurse is monitoring a client who is receiving vancomycin intravenously. Which of the
following findings indicates a potentially serious adverse effect?
A. Mild headache after infusion
B. Redness and flushing of the upper body
C. Serum creatinine increase from 1.0 to 1.8 mg/dL
D. Mild nausea during infusion
-CORRECT ANSWER >-C. Serum creatinine increase from 1.0 to 1.8 mg/dL
Rationale: An increase in serum creatinine indicates nephrotoxicity, a serious potential
adverse effect of vancomycin. Redness and flushing of the upper body, known as “red
man syndrome,” can occur if the infusion is given too rapidly but is usually reversible
and less dangerous. Mild headache and nausea are common side effects. Early detection
of nephrotoxicity allows prompt adjustment of dosage or discontinuation, preventing
permanent kidney damage and ensuring safe administration of vancomycin.
3. A nurse is providing education to a client with type 1 diabetes mellitus about self-
administration of insulin. Which of the following statements by the client indicates
correct understanding?
A. “I will rotate my injection sites to prevent skin problems.”
B. “I can mix long-acting insulin with rapid-acting insulin in the same syringe.”
C. “I will skip my insulin dose if I plan to eat less than usual.”
, D. “I will store my insulin in the freezer to keep it effective.”
-CORRECT ANSWER >-A. “I will rotate my injection sites to prevent skin problems.”
Rationale: Rotating injection sites prevents lipohypertrophy, which can interfere with
insulin absorption. Long-acting insulin should not be mixed with other insulins in the
same syringe, and insulin should not be skipped as this can lead to hyperglycemia or
diabetic ketoacidosis. Insulin should be stored in the refrigerator but not frozen, as
freezing damages its potency. Proper technique and storage ensure effective blood
glucose control and prevent complications.
4. A nurse is caring for a client receiving a blood transfusion. Which of the following
findings requires immediate intervention?
A. Blood pressure of 130/78 mm Hg
B. Client reports itching and hives during transfusion
C. Temperature of 37.5°C (99.5°F)
D. Urine output of 60 mL over 2 hours
-CORRECT ANSWER >-B. Client reports itching and hives during transfusion
Rationale: Itching and hives indicate a possible allergic transfusion reaction. The nurse
should immediately stop the transfusion, maintain IV access with normal saline using
new tubing, and notify the healthcare provider. Blood pressure and mild temperature
changes are expected findings and may not require intervention. Normal urine output
does not indicate a problem. Prompt recognition and management of transfusion reactions
prevent progression to anaphylaxis or other life-threatening complications.
5. A nurse is providing dietary teaching to a client with hypertension who has a new
prescription for hydrochlorothiazide. Which of the following statements indicates
understanding of the teaching?
A. “I should limit foods high in potassium like bananas and oranges.”
B. “I will increase my intake of potassium-rich foods such as potatoes and spinach.”
C. “I will avoid drinking water to prevent swelling.”
D. “I do not need to monitor my weight while taking this medication.”
-CORRECT ANSWER >-B. “I will increase my intake of potassium-rich foods such as
potatoes and spinach.”
Rationale: Hydrochlorothiazide is a thiazide diuretic that can cause potassium loss,
increasing the risk of hypokalemia. Encouraging the intake of potassium-rich foods helps
maintain electrolyte balance and prevent complications such as cardiac dysrhythmias.
Limiting potassium-rich foods is incorrect and increases risk. Clients should not restrict
water unless specifically prescribed, and monitoring weight helps assess fluid status and
, effectiveness of the medication. Proper dietary education enhances medication safety and
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therapeutic effectiveness. ZI
6. A nurse is caring for a client with a urinary tract infection who has been prescribed ciprofl
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oxacin. Which of the following statements by the client indicates a need for further teachi
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ng?
A. “I will complete the entire course of this antibiotic.”
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B. “I can take the medication with or without food.”
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C. “I should increase my fluid intake while taking this medication.”
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D. “I will take this medication with an antacid if I feel stomach upset.”
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-CORRECT ANSWER >-
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D. “I will take this medication with an antacid if I feel stomach upset.”
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Rationale: Ciprofloxacin absorption can be significantly reduced by antacids containing
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magnesium or aluminum, decreasing its effectiveness. Clients should be instructed to take
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ciprofloxacin at least 2 hours before or 6 hours after taking antacids. Completing the full
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course of therapy ensures eradication of the infection. The medication may be taken with
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or without food to reduce gastrointestinal upset. Increasing fluid intake helps prevent crys
ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI
talluria and kidney injury. Proper education promotes effective treatment and prevents ant
ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI
ibiotic resistance or treatment failure.
ZI ZI ZI ZI
7. A nurse is monitoring a client who is receiving vancomycin intravenously. Which of the f
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ollowing findings indicates a potentially serious adverse effect?
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A. Mild headache after infusion
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B. Redness and flushing of the upper body
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C. Serum creatinine increase from 1.0 to 1.8 mg/dL
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D. Mild nausea during infusion
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-CORRECT ANSWER >-C. Serum creatinine increase from 1.0 to 1.8 mg/dL
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Rationale: An increase in serum creatinine indicates nephrotoxicity, a serious potential ad
ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI
verse effect of vancomycin. Redness and flushing of the upper body, known as “red man s
ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI
yndrome,” can occur if the infusion is given too rapidly but is usually reversible and less d
ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI ZI
angerous. Mild headache and nausea are common side effects. Early detection of nephroto
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xicity allows prompt adjustment of dosage or discontinuation, preventing permanent kidn
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ey damage and ensuring safe administration of vancomycin.
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8. A nurse is providing education to a client with type 1 diabetes mellitus about self-
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administration of insulin. Which of the following statements by the client indicates correc
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t understanding?
ZI
A. “I will rotate my injection sites to prevent skin problems.”
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