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PAEA EOC & Summative Practice Exams | Verified Questions & Correct Detailed Answers | Latest A+ Grade | 2025/2026 Edition

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The PAEA End of Curriculum (EOC) & Summative Practice Exams – 2025/2026 Edition study guides are available as verified, A+ graded resources. They provide exam-style practice questions with correct answers and rationales, already graded A+, covering the competencies required for Physician Assistant (PA) students preparing for summative and end-of-program assessments.

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Uploaded on
December 10, 2025
Number of pages
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2025/2026
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PAEA EOC & Summative Practice questions
and answers 2025\2026 A+ Grade

what exactly causes the occlusive vascular disease of thromboangiitis obliterans?
- correct answer aka Buerger's disease



inflammatory thrombi affecting the medium and small vessels (nonatherosclerosis)



polymorphonuclear leukocytes, microabscesses, and multinucleated giant cells may be presen



Treatment options for thromboangiitis obliterans?
- correct answer smoking cessation most important!

cilostazol (PDE 3 inhibitor) has vasodilator properties (alleviated symptoms)

if raynauds also present, CCB (nifedipine)



what heart failure treatment provides a benefit of reduction in morbidity and mortality?
- correct answer ACE inhibitors

beta blockers can also reduce M&M



diuretics have no reduction in mortality



how would you manage a patient with a MI in the setting of cocaine use?
- correct answer benzodiazepine early

no beta blockers



If PCI cannot be done for a STEMI patient within 120 minutes, what should be done?
- correct answer fibrolytic therapy

,then do PCI & coronary angiography when it can be done



ideally PCI is done within 90 minutes



fibrolytic therapy can be used up to 12 hours of symptoms



If you suspect an acute limb ischemia due to arterial embolism, what imaging should you get?
- correct answer catheter-based arteriography (digital subtraction arteriography) provides the most
useful information. can also help with treatment



can help distinguish between thrombosis and embolus



where are arterial emboli often found?
- correct answer lower extremities more common than upper extremities



The common femoral, common iliac, and popliteal artery bifurcations are frequent locations



majority originate in the heart



fun fact: Compared with thromboemboli, atheroemboli are less likely to produce symptoms of acute
limb ischemia



how would you work up a patient with treatment resistant hypertension that you suspect a secondary
cause?
- correct answer 24-hour ambulatory monitoring (to ensure not white coat)

medical hx (assess adherence to meds, other meds)

physical exam (look for abominal/renal bruits)

labs (electrolytes, glucose, creatinine, UA)

,If pheo suspected: measure fractionated metanephrines and catecholamines in a 24-hour urine
collection



other than atherosclerosis leading to renal artery stenosis and secondary HTN, what is another causes of
a renal-associated secondary HTN?
- correct answer fibromuscular dysplasia (usually in a young pt)



most important modifable risk factor for AAA?
- correct answer smoking cessation!



when is it okay to do screening survelliance for AAA rather than repair and how often should you
screen?
- correct answer if AAA is <5.5 cm then annual screening with US is recommended. may need every 6
months if rapidly expanding or other concerns



how should you educate a patient with AAA on exercise?
- correct answer Patients should be counseled that moderate physical activity such as running, biking,
swimming, hiking, or sexual activity and activities such as gardening, golfing, and horseback riding do not
precipitate AAA rupture



Moderate physical therapy may also limit aneurysm expansion. In experimental aneurysms, increased
aortic blood flow appears to inhibit AAA expansion



However, heavy lifting, especially while holding the breath, and other activities that lead to Valsalva
transiently induce significant increases in blood pressure and should be avoided



gold standard for dx renal artery stenosis? what can be used to monitor disease progression?
- correct answer renal arteriography



But really a spiral CT angiography is very useful and probably more likely done first



duplex doppler US can be used to monitor disease progression

, what are some symptoms of mitral valve prolapse syndrome?
- correct answer various nonspecific symptoms such as palpitations, dyspnea, exercise intolerance,
anxiety disorders, and dizziness



since symptoms are relatively uncommon, what physical exam findings are associated with mitral valve
prolapse?
- correct answer non-ejection click in systole



click is mobile, meaning its timing varies with maneuvers that change the left ventricular volume,
occurring earlier in systole with sitting, standing, or other interventions that reduce ventricular size, or
later with those interventions that increase chamber size such as squatting



People with MVP tend to have lower BMIs



how would you distinguish vasospastic angina and angina associated with CAD?
- correct answer quality of the CP is typically indistinguishable of the two



patients with vasospastic angina report that their episodes are predominantly at rest and that many
occur from midnight to early morning, while effort tolerance is usually preserved. CP generally lasts 5 to
15 minutes



Patients with vasospastic angina are often younger and exhibit fewer classic cardiovascular risk factors
and may be associated with other vasospastic disorders, such as Raynaud's phenomenon and migraine
headache



Exercise does not usually provoke an episode of spasm



ECG may reveal transient ST-segment elevation or depression in multiple lead but troponins will not be
elevated



where do karposi sarcoma lesions typically occur? describe their appearance.
- correct answer often on distal extremities, such as lower legs and feet

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