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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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Chapter1,TheFoundationofPharmacology:Quality and Safety
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1. A woman diagnosed with obsessive–compulsive disorder has been prescribedoral
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paroxetine hydrochloride. What is theexpected effect for this prescription?
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A. Curativeeffect on symptoms io io io
B. Systemiceffect on symptoms io io io
C. Localeffect on symptoms io io io
D. Parenteraleffect on symptoms io io io
ANS: B i o
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
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bloodstream to their sites of action in various body tissues, and eventually eliminated from the
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body. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
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will control thesymptoms butnot cure thedisorder. Drugs with local effects,such as sunscreen
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and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not
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administered parenterally. Parenteral agents are administered subcutaneously,
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intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 io io
NAT: i o ClientNeeds: Physiological Integrity: Pharmacological and ParenteralTherapies
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TOP:
io Chapter: 1: TheFoundation of Pharmacology: Qualityand Safety io io io io io io io io
KEY: i o IntegratedProcess: NursingProcess io io io
BLM: i Cognitive Level: Understand
o NOT: Multiple Choice io io i o io
2. A client has been prescribedan antibiotic. This medication isanaturallyoccurring
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substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOtM
.C is another name for this type of
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medication?
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A. Syntheticdrug io
B. Semisynthetic drug io
C. Biotechnologydrug io
D. Prototype drug io
ANS: B i o
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
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havebeen chemicallymodified.Synthetic drugs aremorestandardized in their chemical
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characteristics, more consistent in their effects, and less likely to produce allergic reactions.
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Biotechnology drugs involve manipulating DNA and RNA and recombining genes into hybrid
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molecules that can be inserted into living organisms. Prototype drugs are the first drugof a
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particular group to be developed.
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PTS: 1 REF: p. 3, DrugSources OBJ: 1 io io io
NAT: i o ClientNeeds: Physiological Integrity: Pharmacological and ParenteralTherapies
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TOP:
io Chapter: 1: TheFoundation of Pharmacology: Qualityand Safety io io io io io io io io
KEY: i o IntegratedProcess: NursingProcess io io io
BLM: i Cognitive Level: Understand
o NOT: Multiple Choice io io i o io
3. Whichclassification applies tomorphine? io io io io
A. Centralnervous system depressant io io io
B. Centralnervous system stimulant io io io
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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