NSG 6005 WEEK 6 QUIZ SOUTH UNIVERSITY
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The nurse is obtaining a history from a patient who discloses daily use of St. John's wort in
addition to prescription drugs. Which effect of this dietary supplement would most concern
the nurse?
a. It accelerates the metabolism of some drugs.
b. It enhances the effects of digoxin.
c. It counteracts the effects of CNS depressants.
d. It increases the risk of bleeding
ANS: A
St. John's wort has the potential to interact with many drugs through three different
mechanisms. One mechanism, induction of P450, accelerates the metabolism of many drugs,
causing loss of therapeutic effects. St. John's wort reduces the effects of digoxin, because P-
glycoprotein transports drugs out of tubular cells of the kidney and into the urine, greatly
A+ TEST BANK 1
, NSG 6005 FINAL EXAM
reducing digoxin levels. St. John's wort does not counteract the beneficial effects of CNS
depressants; it can actually intensify the effects of serotonin. St. John's wort is not known to
increase the risk of bleeding
A nurse is performing a preoperative drug history on a patient who is admitted to the hospital
for surgery. To evaluate the risk of hemorrhage, the nurse will ask the patient about
antiplatelet and anticoagulant medications as well as which dietary supplement?
a. Coenzyme Q-10
b. Ginkgo biloba
c. Ma huang (ephedra)
d. St. John's wort
ANS: B
Ginkgo biloba can suppress platelet aggregation and will increase the risk of bleeding in
patients taking antiplatelet medications and anticoagulants. Coenzyme Q-10, Ma huang, and
St. John's wort
do not have antiplatelet actions.
A patient in her twenties has frequent urinary tract infections, and her prescriber suggests
drinking cranberry juice. She asks the nurse how drinking this can help. The nurse will tell her
that cranberry juice:
a. acidifies the urine to slow the growth of the bacteria.
b. helps treat established infections.
c. prevents bacteria from adhering to the urinary tract wall.
d. reduces the odor of the urine.
ANS: C
Cranberry juice helps prevent UTIs by preventing bacteria from adhering to the urinary tract
wall. It does not acidify the urine or treat established infections. It can reduce odor, but this
action does not contribute to decreased infections
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A patient asks a nurse how to know whether dietary supplements are safe. The nurse will tell
this patient that:
a. any standards addressing safety merely regulate labeling and manufacturing processes.
b. manufacturers must provide the FDA with efficacy claims prior to marketing their
supplements.
c. the DSHEA requires labeling that prohibits claims of treatment of specific diseases or
conditions.
d. the FDA must approve dietary supplements prior to marketing them in the United States.
ANS: A
Dietary supplements are regulated under the Dietary Supplement Health and Education Act
of 1994 (DSHEA). This special category exempts them from the scrutiny applied to foods and
drugs. A set of standards issued by the FDA in 2007 is designed to ensure that supplements
are devoid of adulterants, contaminants, and impurities and that labels reflect the contents—
these standards do not ensure safety and efficacy. Efficacy claims must be provided but are
not required to prove these claims; a claim to efficacy does not guarantee safety. Regulations
prohibiting disease- specific claims do not ensure safety. The FDA does not approve dietary
supplements prior to marketing
A patient admitted to the emergency department with abdominal pain tells the nurse he has
been taking kava. Which action is the nurse's priority at this time?
a. Review liver function studies.
b. Assess breath sounds and respiratory effort.
c. Monitor cardiovascular status.
d. Review complete blood count results.
ANS: A
Kava can cause severe liver injury and, in some cases, require liver transplantation. This
patient has abdominal pain, which can be the result of liver damage, so liver function tests
should be reviewed. Kava does not affect the respiratory system, the cardiovascular system,
or the blood- forming organs
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A patient will begin taking immunosuppressant drugs for rheumatoid arthritis. The nurse will
caution this patient to avoid which dietary supplement?
a. Black cohosh
b. Echinacea
c. Feverfew
d. Glucosamine
ANS: B
Echinacea stimulates the immune system so it should not be used in patients with
autoimmune disease such as RA; it also compromises the effectiveness of
immunosuppressive drugs. Black cohosh, feverfew, and glucosamine are not contraindicated
in patients with RA
A nursing student asks a nurse what the NMBER system that rates dietary supplements
means. The nurse responds that the NMBER system:
a. describes the chemistry, toxicology, pharmacology, and uses of supplements.
b. helps consumers evaluate the safety and efficacy of products.
c. provides free information about clinical trials and epidemiologic studies of products.
d. provides funding for research on complementary and alternative medicine.
ANS: B
The Natural Medicines Brand Evidence-Based Rating (NMBER) system offers evidence-based
ratings for over 60,000 supplement products based on scientific evidence of safety and
efficacy. Information from this system does not describe the chemistry, toxicology,
pharmacology, and uses of the products or describe data from clinical trials. There is a fee for
use of this system. The system does not fund research on these products
A nurse discusses ginger root with a pregnant patient who asks about the risks and benefits
of using ginger root to treat morning sickness during pregnancy. Which statement by the
patient indicates a need for further teaching?
a. "Ginger root can cause GI disturbance in high doses."
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