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Clinical Chem Test Bank (Final Exam) EXAM 2025/2026 BANK
2025/2026 BANK 2 VERSIONS QUESTIONS AND ACCURATE
ACTUAL EXAM WITH FREQUENTLY TESTED QUESTIONS AND
STUDY GUIDE / EXPERT VERIFIED FOR GUARANTEED
PASS/ALREADY GRADED A+
1. In which of the following disorders would the maternal serum
level of 1-fetoprotein be elevated?
A. Neural tube defect.
B. Cardiac ischemia.
C. Down syndrome.
D. Small cell lung carcinoma - ANSWERS--A. Neural tube defect
2. Which of the following is FALSE about PSA?
A. It is a single-chain glycoprotein
B. It is used as a tumor marker
C. It is not elevated in benign prostatic hyperplasia
D. It is quantified in serum by immunoassays - ANSWERS--C. It is not
elevated in benign prostatic hyperplasia.
3. Which of the following biomarkers is elevated in nonmucinous
epithelial ovarian cancer?
A. CA 15-3
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B. CA 19-9
C. CA 125
D. CEA - ANSWERS--C. CA 125
4. Which of the following is a sialylated Lewis blood group antigen
associated with colorectal cancer?
A. CA 125
B. CA 15-3
C. PSA
D. CA 19-9 - ANSWERS--D. CA 19-9
5. Which of the following biomarkers are elevated in advanced
stages of breast cancer?
A. Total and free PSA
B. CEA and alpha-fetoprotein
C. CA 15-3 and CA 549
D. DUPAN-2 and Gastrin - ANSWERS--C. CA 15-3 and CA 549
6. Which tumor marker is associated with cancer of the urinary
bladder?
A. CA 125
B. CA19-9
C. CA 50
D. Nuclear matrix protein - ANSWERS--D. Nuclear matrix protein
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7. What is the primary clinical usefulness of measuring
carcinoembryonic antigen?
A. Diagnosis of lung cancer
B. Diagnosis of colorectal cancer
C. Screening for breast cancer
D. Monitoring for recurrence of colon cancer - ANSWERS--D.
Monitoring for recurrence of colon cancer
8. Which of the following is used to assess the usefulness of
trastuzumab (Herceptin®) therapy for breast cancer?
A. CA 15-3
B. HER-2/neu
C. CA 125
D. Prolactin - ANSWERS--B. HER-2/neu
9. Which type of hCG test would be most useful to assess a person
suspected of having testicular cancer?
A. Plasma immunoassay for intact hCG and the β-hCG subunits
B. Plasma immunoassay fro the free alpha and β-hCG subunits
C. Urine assay for hCG-β core
D. Plasma immunoassay for intact hCG only - ANSWERS--A. Plasma
immunoassay for intact hCG and the β-hCG subunits
10. A markedly elevated serum AFP is associated with which of the
following?
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A. Ovarian cancer
B. Lung cancer
C. Hepatoma
D. Breast cancer - ANSWERS--C. Hepatoma
11. Which of the following assays is recommended as a screening
test for colorectal cancer in persons over 50 years of age?
A. Fecal typsin
B. AFP
C. BTA
D. Occult blood t test - ANSWERS--D. Occult blood test
12. Which of the following must be determined to calculate
diagnostic specificity?
A. True-negatives and false-positives
B. True-positives and false-positives
C. True-positives and false-negatives
D. True-negatives and false-negatives - ANSWERS--A. True-negatives
and false-positives
13. A new tumor marker assay for prostate specific antigen (PSA) is
evaluated for sensitivity by testing serum samples from patients who
have been diagnosed as having prostate cancer. The following results
were obtained:
Number of prostate cancer patients who tested positive by the new
assay = 42 out 46
Clinical Chem Test Bank (Final Exam) EXAM 2025/2026 BANK
2025/2026 BANK 2 VERSIONS QUESTIONS AND ACCURATE
ACTUAL EXAM WITH FREQUENTLY TESTED QUESTIONS AND
STUDY GUIDE / EXPERT VERIFIED FOR GUARANTEED
PASS/ALREADY GRADED A+
1. In which of the following disorders would the maternal serum
level of 1-fetoprotein be elevated?
A. Neural tube defect.
B. Cardiac ischemia.
C. Down syndrome.
D. Small cell lung carcinoma - ANSWERS--A. Neural tube defect
2. Which of the following is FALSE about PSA?
A. It is a single-chain glycoprotein
B. It is used as a tumor marker
C. It is not elevated in benign prostatic hyperplasia
D. It is quantified in serum by immunoassays - ANSWERS--C. It is not
elevated in benign prostatic hyperplasia.
3. Which of the following biomarkers is elevated in nonmucinous
epithelial ovarian cancer?
A. CA 15-3
,2|Page
B. CA 19-9
C. CA 125
D. CEA - ANSWERS--C. CA 125
4. Which of the following is a sialylated Lewis blood group antigen
associated with colorectal cancer?
A. CA 125
B. CA 15-3
C. PSA
D. CA 19-9 - ANSWERS--D. CA 19-9
5. Which of the following biomarkers are elevated in advanced
stages of breast cancer?
A. Total and free PSA
B. CEA and alpha-fetoprotein
C. CA 15-3 and CA 549
D. DUPAN-2 and Gastrin - ANSWERS--C. CA 15-3 and CA 549
6. Which tumor marker is associated with cancer of the urinary
bladder?
A. CA 125
B. CA19-9
C. CA 50
D. Nuclear matrix protein - ANSWERS--D. Nuclear matrix protein
,3|Page
7. What is the primary clinical usefulness of measuring
carcinoembryonic antigen?
A. Diagnosis of lung cancer
B. Diagnosis of colorectal cancer
C. Screening for breast cancer
D. Monitoring for recurrence of colon cancer - ANSWERS--D.
Monitoring for recurrence of colon cancer
8. Which of the following is used to assess the usefulness of
trastuzumab (Herceptin®) therapy for breast cancer?
A. CA 15-3
B. HER-2/neu
C. CA 125
D. Prolactin - ANSWERS--B. HER-2/neu
9. Which type of hCG test would be most useful to assess a person
suspected of having testicular cancer?
A. Plasma immunoassay for intact hCG and the β-hCG subunits
B. Plasma immunoassay fro the free alpha and β-hCG subunits
C. Urine assay for hCG-β core
D. Plasma immunoassay for intact hCG only - ANSWERS--A. Plasma
immunoassay for intact hCG and the β-hCG subunits
10. A markedly elevated serum AFP is associated with which of the
following?
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A. Ovarian cancer
B. Lung cancer
C. Hepatoma
D. Breast cancer - ANSWERS--C. Hepatoma
11. Which of the following assays is recommended as a screening
test for colorectal cancer in persons over 50 years of age?
A. Fecal typsin
B. AFP
C. BTA
D. Occult blood t test - ANSWERS--D. Occult blood test
12. Which of the following must be determined to calculate
diagnostic specificity?
A. True-negatives and false-positives
B. True-positives and false-positives
C. True-positives and false-negatives
D. True-negatives and false-negatives - ANSWERS--A. True-negatives
and false-positives
13. A new tumor marker assay for prostate specific antigen (PSA) is
evaluated for sensitivity by testing serum samples from patients who
have been diagnosed as having prostate cancer. The following results
were obtained:
Number of prostate cancer patients who tested positive by the new
assay = 42 out 46