NIH PRINCIPLES AND PRACTICES OF CLINICAL
RESEARCH IPPCR EXAMINATION TEST 2026
QUESTIONS WITH ANSWERS GRADED A+
◉ Hippocrates. Answer: Father of modern medicine; Hipprocratic oath -
-> high moral standards.
◉ Which of the following is most likely a case series study? Answer:
Report of 5 cases of pneumocytosis pneumonia in previously healthy
homosexual men
◉ Scientific misconduct can cause which of the following? Answer: All
of the above
◉ What is/are the reason(s) that NIH requires the inclusion of women
and minorities in all clinical research? Answer: All of the above
◉ What can change a study's power and how power is impacted?
Answer: Variation in outcome (σ2): power decreases as an outcome's
variance increases
, ◉ A for-cause audit conducted by the Food and Drug Administration is
best described as: Answer: An audit performed to investigate possible
fraud or misconduct
◉ The use of common data elements (CDEs) should meet all of the
following objectives EXCEPT: Answer: To promote unneeded or
redundant data collection
◉ True or False: Tests of general cognitive function, such as IQ tests and
mini-mental status exams (MMSE), provide effective tools for
determining whether individuals can give informed consent for a clinical
trial. Answer: False
◉ An h-index is a way to: Answer: Measure an author's productivity and
impact
◉ Clinical trial registration is important so that: Answer: A and B only
a) existing trials are publicly available; b) Trials are made publicly
available even if they are not finished
◉ It is important to be able to replicate the randomization results, i.e.,
reproduce the string of treatment assignments. Answer: False
◉ Scientific misconduct includes all of the following EXCEPT: Answer:
human error
RESEARCH IPPCR EXAMINATION TEST 2026
QUESTIONS WITH ANSWERS GRADED A+
◉ Hippocrates. Answer: Father of modern medicine; Hipprocratic oath -
-> high moral standards.
◉ Which of the following is most likely a case series study? Answer:
Report of 5 cases of pneumocytosis pneumonia in previously healthy
homosexual men
◉ Scientific misconduct can cause which of the following? Answer: All
of the above
◉ What is/are the reason(s) that NIH requires the inclusion of women
and minorities in all clinical research? Answer: All of the above
◉ What can change a study's power and how power is impacted?
Answer: Variation in outcome (σ2): power decreases as an outcome's
variance increases
, ◉ A for-cause audit conducted by the Food and Drug Administration is
best described as: Answer: An audit performed to investigate possible
fraud or misconduct
◉ The use of common data elements (CDEs) should meet all of the
following objectives EXCEPT: Answer: To promote unneeded or
redundant data collection
◉ True or False: Tests of general cognitive function, such as IQ tests and
mini-mental status exams (MMSE), provide effective tools for
determining whether individuals can give informed consent for a clinical
trial. Answer: False
◉ An h-index is a way to: Answer: Measure an author's productivity and
impact
◉ Clinical trial registration is important so that: Answer: A and B only
a) existing trials are publicly available; b) Trials are made publicly
available even if they are not finished
◉ It is important to be able to replicate the randomization results, i.e.,
reproduce the string of treatment assignments. Answer: False
◉ Scientific misconduct includes all of the following EXCEPT: Answer:
human error
