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Fall & Thanksgiving Season 2025/2026 — ATI CMS Pharmacology Exam Prep with 330 High-Yield Questions & Updated Rationales | Latest Comprehensive Study Guide

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This fully updated Fall & Thanksgiving Season 2025/2026 ATI CMS Pharmacology Study Guide includes 330 high-yield exam questions with detailed rationales, designed to match the latest ATI CMS Pharmacology testing blueprint. Includes medication classifications, priority nursing interventions, side effects, safety alerts, NCLEX-style items, therapeutic monitoring, and dosage calculation review. Perfect for ATI CMS retakes, nursing school exams, pharmacology finals, and comprehensive ATI assessments.

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ATI CMS PHARMACOLOGY
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Institution
ATI CMS PHARMACOLOGY
Course
ATI CMS PHARMACOLOGY

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Uploaded on
November 29, 2025
Number of pages
98
Written in
2025/2026
Type
Exam (elaborations)
Contains
Questions & answers

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Fall & Thanksgiving Season 2025/2026 — ATI CMS
Pharmacology Exam Prep with 330 High-Yield
Questions & Updated Rationales | Latest
Comprehensive Study Guide
Question 1: What is the primary action of beta-blockers?
• A) Increase heart rate
• B) Decrease heart rate
• C) Enhance cardiac contractility
• D) Promote vasodilation
CORRECT ANSWER: B) Decrease heart rate
Rationale: Beta-blockers block the effects of epinephrine, leading to a decrease in
heart rate and blood pressure.


Question 2: Which of the following medications is an example of a loop diuretic?
• A) Hydrochlorothiazide
• B) Furosemide
• C) Spironolactone
• D) Bumetanide
CORRECT ANSWER: B) Furosemide
Rationale: Furosemide is a loop diuretic that inhibits sodium and chloride reabsorption
in the ascending loop of Henle.


Question 3: What is the primary purpose of anticoagulant therapy?
• A) To promote blood clot formation
• B) To reduce blood pressure
• C) To prevent blood clot formation
• D) To increase blood volume
CORRECT ANSWER: C) To prevent blood clot formation
Rationale: Anticoagulants prevent clots in blood vessels, reducing the risk of
thrombosis and embolism.


Question 4: Which of the following is a common side effect of opioid analgesics?
• A) Constipation

, • B) Hyperactivity
• C) Insomnia
• D) Hypertension
CORRECT ANSWER: A) Constipation
Rationale: Opioids often slow gastrointestinal motility, leading to constipation.


Question 5: What is the therapeutic use of acetaminophen?
• A) Anti-inflammatory
• B) Analgesic and antipyretic
• C) Anticoagulant
• D) Antibiotic
CORRECT ANSWER: B) Analgesic and antipyretic
Rationale: Acetaminophen is primarily used to relieve pain and reduce fever.


Question 6: Which class of drugs is primarily used to treat hypertension?
• A) Anticoagulants
• B) Opioids
• C) Antihypertensives
• D) Antidepressants
CORRECT ANSWER: C) Antihypertensives
Rationale: Antihypertensives are designed to lower blood pressure.


Question 7: What is the mechanism of action of ACE inhibitors?
• A) Inhibit the conversion of angiotensin I to angiotensin II
• B) Block beta-adrenergic receptors
• C) Increase sodium reabsorption
• D) Promote vasodilation through calcium channel blockade
CORRECT ANSWER: A) Inhibit the conversion of angiotensin I to angiotensin II
Rationale: ACE inhibitors reduce levels of angiotensin II, leading to lower blood
pressure.

,Question 8: Which medication is commonly used as a first-line treatment for type 2
diabetes?
• A) Insulin
• B) Sulfonylureas
• C) Metformin
• D) GLP-1 agonists
CORRECT ANSWER: C) Metformin
Rationale: Metformin is often the first-line treatment due to its efficacy and safety
profile.


Question 9: What is the primary side effect of statins?
• A) Drowsiness
• B) Hypertension
• C) Muscle pain (myopathy)
• D) Tachycardia
CORRECT ANSWER: C) Muscle pain (myopathy)
Rationale: Statins can cause muscle pain or damage as a side effect, known as
myopathy.


Question 10: Which of the following should be monitored closely in patients taking
lithium?
• A) Blood glucose levels
• B) Renal function and thyroid levels
• C) Liver function tests
• D) Electrolyte imbalances
CORRECT ANSWER: B) Renal function and thyroid levels
Rationale: Lithium can affect kidney function and thyroid hormone levels, necessitating
regular monitoring.
Question 11: Which of the following is a common side effect of corticosteroids?
• A) Weight loss

, • B) Weight gain
• C) Increased energy
• D) Insomnia
CORRECT ANSWER: B) Weight gain
Rationale: Corticosteroids can lead to weight gain due to increased appetite and fluid
retention.


Question 12: What class of medication is used to treat bacterial infections?
• A) Antivirals
• B) Antibiotics
• C) Antifungals
• D) Antiparasitics
CORRECT ANSWER: B) Antibiotics
Rationale: Antibiotics are specifically designed to combat bacterial infections.


Question 13: Which of the following is an adverse effect of digoxin?
• A) Increased heart rate
• B) Bradycardia
• C) Hypertension
• D) Tachycardia
CORRECT ANSWER: B) Bradycardia
Rationale: Digoxin can slow the heart rate, potentially leading to bradycardia.


Question 14: What monitoring parameter is crucial for patients on warfarin?
• A) INR (International Normalized Ratio)
• B) Blood glucose
• C) Heart rate
• D) Liver function tests
CORRECT ANSWER: A) INR (International Normalized Ratio)

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