Test Bank
,PsychopharmacologyqwDrugsqwtheqwBrainqwAndqwBehaviorqw3rdqwEditionqwmeyerqwN
ursingqwTestqwBank
TestqwBank
toqwaccompany
Psychopharmacology,qwThirdqwEdition
Meyerqw•qwQuenzer
Chapter 1: Principles of Pharmacology
qw qw qw qw
MultipleqwChoice
1. refer(s)qwtoqwspecificqwmolecularqwchangesqwthatqwoccurqwwhenqwaqwdrugqwbind
sqwtoqwaqwparticularqwtargetqwsiteqworqwreceptor,qwwhile
areqwtheqwresultingqwwidespreadqwalterationsqwinqwfunction.
a. Drugqwaction;qwtherapeuticqweffects
b. Sideqweffects;qwdrugqweffects
c. Therapeuticqweffects;qwsideqweffects
d. Drugqwaction;qwdrugqweffects
Answer:qwd
TextbookqwReference:qwPharmacology:qwTheqwScienceqwofqwDrugqwAction
2. Afterqwdrugqwadministrationqwhasqwoccurred,qwtheqwamountqwofqwdrugqwinqwtheqwbloodqw
thatqwisqwfreeqwtoqwbindqwatqwspecificqwtargetqwsitesqwisqwreferredqwtoqwas
a. theqwtherapeuticqwdose.
b. first-passqweffects.
c. bioavailability.
d. ED50.
Answer:qwc
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
3. Theqwspecificqwmolecularqwchangesqwthatqwoccurqwwhenqwaqwdrugqwbindsqwtoqwaqwpartic
ularqwtargetqwsiteqworqwreceptorqwareqwreferredqwtoqwas
a. drugqweffects.
b. drugqwaction.
c. sideqweffects.
d. placeboqweffects.
Answer:qwb
TextbookqwReference:qwPharmacology:qwTheqwScienceqwofqwDrugqwAction
4. Whichqwofqwtheqwfollowingqwisqwnotqwaqwpossibleqwexplanationqwforqwplaceboqweffects?
a. Pavlovianqwconditioning
b. Geneticqwvariation
c. Drugqwcompetition
d. Expectationqwofqwoutcome
Answer:qwc
TextbookqwReference:qwPharmacology:qwTheqwScienceqwofqwDrugqwAction
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,PsychopharmacologyqwDrugsqwtheqwBrainqwAndqwBehaviorqw3rdqwEditionqwmeyerqwN
ursingqwTestqwBank
5. The
administrationqwofqwoxytocinqwhasqwbeenqwproposedqwasqwaqwtreatmentqwforqwauti
sm.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:qwc
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
6. Whichqwfactorqwdoesqwnotqwaffectqwtheqwpharmacokineticsqwofqwaqwdrug?
a. Routeqwofqwadministration
b. Lipidqwsolubility
c. Depotqwbinding
d. Drugqwaction
Answer:qwd
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
7. First-passqwmetabolismqwoccursqwwhenqwdrugsqwareqwtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:qwa
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
8. Theqwareaqwpostremaqwisqwoneqwareaqwinqwtheqwbrainqwwhereqwthe isqwnotqwcomplete.
a. cerebrospinalqwfluid
b. blood–brainqwbarrier
c. choroidqwplexus
d. phospholipidqwmembrane
Answer:qwb
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
9. First-passqwmetabolismqwoccursqwwithqworallyqwadministeredqwdrugsqwbecause
a. theirqwabsorptionqwisqwslowedqwbyqwfood.
b. drugsqwabsorbedqwintoqwtheqwbloodstreamqwfromqwtheqwstomachqwgoqwtoqwtheqwliverqw
onqwtheqwwayqwtoqwgeneralqwcirculation.
c. drugsqwmustqwfirstqwsurviveqwtheqwacidicqwenvironmentqwofqwtheqwstomach.
d. salivaryqwenzymesqwinqwtheqwmouthqwbeginqwtheqwprocessqwofqwmetabolism.
Answer:qwb
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
10. Toxicqwsubstancesqwinqwtheqwbloodqwtriggerqwaqwvomitingqwresponseqwbyqwactivatingqwthe
a. blood–brainqwbarrier.
b. choroidqwplexus.
c. areaqwpostrema.
d. medianqweminence.
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, PsychopharmacologyqwDrugsqwtheqwBrainqwAndqwBehaviorqw3rdqwEditionqwmeyerqwN
ursingqwTestqwBank
Answer:qwc
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
11. Drugsqwadministeredqw_ haveqwtheqwmostqwrapidqwonsetqwofqwaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:qwd
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
12. Ionizationqwofqwaqwdrugqwdependsqwonqwthe ofqwtheqwsolutionqwandqwthe
ofqwtheqwdrug.
a.q w pH;qwpK
a
b.q w q w pK ;qwpH
a
c.
q w concentration;qwlipidqwsolubility
d.
q w pH;qwconcentration
Answer:qwa
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
13. Theqwabsorptionqwofqwaqwdrugqwdependsqwonqwallqwofqwtheqwfollowingqwexcept
a. lipidqwsolubility.
b. ionization.
c. bodyqwtemperature.
d. theqwconcentrationqwofqwtheqwdrug.
Answer:qwc
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
14. Drugsqwthatqware shouldqwbeqwavoidedqwbyqwwomenqwofqwchildbearingqwage.
a. teratogenic
b. ableqwtoqwcrossqwtheqwplacentalqwbarrier
c. psychoactive
d. highlyqwlipid-soluble
Answer:qwa
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
15. Agentsqwthatqwinduceqwdevelopmentalqwabnormalitiesqwinqwaqwfetusqwareqwknownqwas
a. psychoactiveqwdrugs.
b. illicitqwdrugs.
c. teratogens.
d. placentalqwdrugs.
Answer:qwc
TextbookqwReference:qwPharmacokineticqwFactorsqwDeterminingqwDrugqwAction
16. Depotqwbindingqwisqwsaidqwtoqwoccurqwwhenqwdrugs
a. bindqwtoqwtheirqwtargetqwsites.
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